| Identification | More | [Name]
Propargyl alcohol | [CAS]
107-19-7 | [Synonyms]
2-PROPYN-1-OL
2-Propyny-1-0l
2-propynyl alcohol
ETHYNYL CARBINOL
ethynyl methanol
LABOTEST-BB LT01409238
PROPARGYL ALCOHOL
PROPINOL
PROPYNOL
PROPYNYL ALCOHOL
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
1-Propyne-3-ol
2-propyn-1-ol (propargyl alcohol)
2-Propynol
3-Hydrlxyallylene
3-Hydroxy-1-propyne
3-Propynol
acetylenecarbinol | [EINECS(EC#)]
203-471-2 | [Molecular Formula]
C3H4O | [MDL Number]
MFCD00002912 | [Molecular Weight]
56.06 | [MOL File]
107-19-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Propargyl alcohol is a colorless liquid with a
geranium-like odor. | [Melting point ]
-53 °C | [Boiling point ]
114-115 °C(lit.) | [density ]
0.963 g/mL at 25 °C(lit.)
| [vapor density ]
1.93 (vs air)
| [vapor pressure ]
11.6 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.432(lit.)
| [Fp ]
97 °F
| [storage temp. ]
2-8°C
| [solubility ]
soluble in Chloroform, Ethyl Acetate | [form ]
Liquid | [pka]
13.6(at 25℃) | [color ]
Clear colorless to slightly yellow | [Odor]
at 100.00 %. geranium | [Odor Type]
floral | [Water Solubility ]
miscible | [Merck ]
14,7809 | [BRN ]
506003 | [Exposure limits]
No exposure limit has been set for 2-propyn1-ol. A TLV-TWA of 1 ppm (～2.3 mg/m3)
should be appropriate for this compound.
This estimation is based on its similarity to
allyl alcohol in chemical properties and toxic
actions. | [LogP]
-0.35 at 25℃ | [Uses]
Chemical intermediate, corrosion inhibitor,
lab reagent, solvent stabilizer, prevents hydrogen
embrittlement of steel, soil fumigant.
| [CAS DataBase Reference]
107-19-7(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Propyn-1-ol(107-19-7) | [EPA Substance Registry System]
107-19-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
R10:Flammable.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R34:Causes burns.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 2929 6.1/PG 1
| [WGK Germany ]
2
| [RTECS ]
UK5075000
| [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29052990 | [Safety Profile]
Poison by ingestion,
skin contact, and subcutaneous routes.
Moderately toxic by inhalation. A central
nervous system depressant. A skin and
mucous membrane irritant. Mutation data
reported. Flammable liquid and dangerous
fire hazard when exposed to heat or flame;
can ignite. To fight fire, use foam, CO2, dry
chemical. Potentially explosive reactions
with alkalies (when dried), sulfuric acid.
Ignites on contact with phosphorus
pentaoxide. Violent reaction with
mercury(Ⅱ) sulfate + sulfuric acid + water
(at 70°C). Incompatible with oxidizing
materials. When heated to decomposition it
emits acrid smoke and irritating fumes. Used
as a corrosion inhibitor, solvent stabilizer,
soil fumigant, and chemical intermediate.
See also ACETYLENE COMPOUNDS. | [Hazardous Substances Data]
107-19-7(Hazardous Substances Data) | [Toxicity]
LD50 in rats, mice (mg/kg): 20, 50 orally (Guilian, Naibin) |
| Hazard Information | Back Directory | [General Description]
A dark liquid with a "fishlike" odor. Less dense than water. Flash point 90°F. Boiling point is 239°F. Corrosive and contact may severely irritate skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals. | [Reactivity Profile]
PROPARGYL ALCOHOL, FATTY ACID DERIVED AMINES is an aminoalcohol mixture. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. When phosphorus pentaoxide is added to PROPARGYL ALCOHOL caused ignition. Acetyl bromide reacts violently with alcohols or water [Merck 11th ed. 1989]. Mixtures of alcohols with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions. Example: An explosion will occur if dimethylbenzylcarbinol is added to 90% hydrogen peroxide then acidified with concentrated sulfuric acid. Mixtures of ethyl alcohol with concentrated hydrogen peroxide form powerful explosives. Mixtures of hydrogen peroxide and 1-phenyl-2-methyl propyl alcohol tend to explode if acidified with 70% sulfuric acid [Chem. Eng. News 45(43):73 1967; J, Org. Chem. 28:1893 1963]. Alkyl hypochlorites are violently explosive. They are readily obtained by reacting hypochlorous acid and alcohols either in aqueous solution or mixed aqueous-carbon tetrachloride solutions. Chlorine plus alcohols would similarly yield alkyl hypochlorites. They decompose in the cold and explode on exposure to sunlight or heat. Tertiary hypochlorites are less unstable than secondary or primary hypochlorites [NFPA 491 M 1991]. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence [Wischmeyer 1969]. | [Air & Water Reactions]
Highly flammable. Soluble in water. | [Hazard]
Flammable, moderate fire risk. Toxic by
ingestion, inhalation, and skin absorption. Eye irri-
tant, liver and kidney damage.
| [Health Hazard]
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. | [Potential Exposure]
Propargyl alcohol is used as
a corrosion inhibitor, soil fumigant; solvent, stabilizer, and
chemical intermediate. | [Fire Hazard]
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, includ-
ing resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medi-
cal attention. Give large quantities of water and induce
vomiting. Do not make an unconscious person vomit. | [Shipping]
UN1986 Alcohols, flammable, toxic, n.o.s.,
Hazard Class: 3; Labels: 3-Flammable liquid, 6.1-
Poisonous materials, Technical Name Required. UN2929
Toxic liquids, flammable, organic, n.o.s., Hazard class: 6.1; | [Incompatibilities]
Vapor may form explosive mixture with
air. Incompatible with oxidizers (chlorates, nitrates, perox-
ides, permanganates, perchlorates, chlorine, bromine, fluo-
rine, etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, epoxides, phosphorus pentoxide. May polymerize
under the influence of heat, oxidizers, peroxides, light.
Attacks many plastics. | [Chemical Properties]
clear colourless to slightly yellow liquid | [Chemical Properties]
Propargyl alcohol is a colorless liquid with a
geranium-like odor. | [Waste Disposal]
Wear protective eye protec-
tion, gloves and clothing to prevent any reasonable proba-
bility of skin or eye contact. Safety equipment suppliers/
manufacturers can provide recommendations on the most
protective glove/clothing material for your operation. All
protective clothing (suits, gloves, footwear, headgear)
should be clean, available each day, and put on before
work. Contact lenses should not be worn when working
with this chemical. Wear splash-proof chemical goggles
and face shield when working with liquid full facepiece
respiratory protection is worn. Employees should wash
immediately with soap when skin is wet or contaminated.
Provide emergency showers and eyewash. | [Definition]
ChEBI: A terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1. | [Production Methods]
Propargyl alcohol is the major commercially available acetylenic
primary alcohol. Propargyl alcohol is a byproduct
of butynediol production. In the usual high-pressure
butynediol process, about 5% of the product is propargyl
alcohol. Some processes give higher proportions of propargyl
alcohol. | [Flammability and Explosibility]
Flammable | [storage]
2-Propyn-1-ol is stored in stainless steellined, glass-lined, or phenolic-lined tanks ordrums. Unlined steel containers may be usedif free of rust. Aluminum, rubber, and epoxymaterials should not be used. Use protectivewear when handling. Wash thoroug. | [Purification Methods]
The commercial material contains a stabiliser. An aqueous solution of propargyl alcohol can be concentrated by azeotropic distillation with butanol or butyl acetate. Dry it with K2CO3 and distil it under reduced pressure, in the presence of about 1% succinic acid, through a glass helices-packed column. [Beilstein 1 IV 2214.] |
|