| Identification | More | [Name]
3-tert-Butoxycarbonylphenylboronic acid | [CAS]
220210-56-0 | [Synonyms]
3-(T-BUTOXYCARBONYL)PHENYLBORONIC ACID
3-(TERT-BUTOXYCARBONYL)BENZENEBORONIC ACID
3-(TERT-BUTOXYCARBONYL)PHENYLBORONIC ACID
T-BUTYL 3-BORONOBENZOATE
3-(Tert-Butoxycarbonyl)Phenylb
3-(tert-Butoxycarbonyl)benzeneboronic acid 98%
3-(T-BUTOXYCARBONYL)PHENYLBORBONIC ACID
tert-Butyl 3-boronobenzoate | [EINECS(EC#)]
691-957-9 | [Molecular Formula]
C11H15BO4 | [MDL Number]
MFCD01630855 | [Molecular Weight]
222.05 | [MOL File]
220210-56-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White to light yellow crystal powde | [Melting point ]
96-102°C | [Boiling point ]
375.0±44.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [storage temp. ]
Keep Cold | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
7.72±0.10(Predicted) | [color ]
White to Almost white | [CAS DataBase Reference]
220210-56-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant/Keep Cold | [HS Code ]
29319000 |
| Hazard Information | Back Directory | [Chemical Properties]
White to light yellow crystal powde | [Preparation]
The 10L glass reactor is equipped with mechanical stirring, thermometer and constant pressure dropping funnel. Under nitrogen protection, add 3 moles of raw material m-carboxybenzene boric acid and 4kg tetrahydrofuran. Add 4.5 moles of thionyl chloride dropwise under reflux and stirring, react for 4 hours, cool to 0-5°C, add 7.5 moles of potassium tert-butoxide in batches, continue stirring for 1 hour after the addition, add 2kg of water, and acidify with acetic acid. Let sit and let the liquid separate. The organic phase was concentrated to obtain a crude product, which was recrystallized by adding 2 kg of petroleum ether to obtain a solid product, 3-tert-Butoxycarbonylphenylboronic acid, with a purity of 98% and a molar yield of 95%. |
|
|