| Identification | More | [Name]
3-Fluoro-4-methoxyaniline | [CAS]
366-99-4 | [Synonyms]
3-FLUORO-4-ANISIDINE
3-FLUORO-4-METHOXYANILINE
3-FLUORO-P-ANISIDINE
4-AMINO-2-FLUOROANISOLE
3-Fluoro-4-Methoxyaniline 2-Fluoro-4-Aminoanisole
4-Amino-2-fluoroanisol
3-Fluoro-p-anisidine (NH2=1)
3-Fluoro-4-methoxy-phenylamine
3-Fluoro-4-methoxyaniline, 98+%
4-Amino-2-fluoro-1-methoxybenzene | [EINECS(EC#)]
627-615-2 | [Molecular Formula]
C7H8FNO | [MDL Number]
MFCD00075040 | [Molecular Weight]
141.14 | [MOL File]
366-99-4.mol |
| Chemical Properties | Back Directory | [Appearance]
light beige to yellow-brown crystalline powder | [Melting point ]
81-83 °C (lit.) | [Boiling point ]
135 °C/18 mmHg (lit.) | [density ]
1.1382 (estimate) | [Fp ]
>110°C | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
4.18±0.10(Predicted) | [color ]
Light beige to yellow-brown | [BRN ]
2717083 | [CAS DataBase Reference]
366-99-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,T | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S38:In case of insufficient ventilation, wear suitable respiratory equipment .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214200 |
| Hazard Information | Back Directory | [Chemical Properties]
light beige to yellow-brown crystalline powder | [Uses]
3-Fluoro-4-methoxyaniline was used as a reagent in the synthesis of novel leucine ureido derivatives which have potent inhibitory activity againt aminopeptidase N. Also used in the synthesis of novel mGluR1 antagonists for the treatment of chronic pain. | [General Description]
Arrhenius parameter has been measured for the reactions of 3-fluoro-p-anisidine (3-fluoro-4-methoxyaniline) with picryl chloride. |
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