| Identification | More | [Name]
Ethyl indole-2-carboxylate | [CAS]
3770-50-1 | [Synonyms]
1H-INDOLE-2-CARBOXYLIC ACID, ETHYL ESTER
2-CARBETHOXYINDOLE
ETHYL 1H-INDOLE-2-CARBOXYLATE
ETHYL 2-INDOLECARBOXYLATE
ETHYL INDOLE-2-CARBOXYLATE
INDOLE-2-CARBOXYLIC ACID ETHYL ESTER
SPECS AF-966/00545036
TIMTEC-BB SBB003670
Ethylindole-2-carboxylicacid
(2S)-2{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoic acid
2-INDOLECARBOXYLICACIDETHYLESTER
Ethyl fluoroindole-2-carboxylate
1-INDO-2-CARBOXYLIC ACID ETHYL ESTER
ICA-OEt
Ethyl indole-2-carboxylate, 98+%
Ethyl indole-2-carboxylate ,97% | [EINECS(EC#)]
223-206-4 | [Molecular Formula]
C11H11NO2 | [MDL Number]
MFCD00005609 | [Molecular Weight]
189.21 | [MOL File]
3770-50-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellow crystals or crystalline powder | [Melting point ]
122-125 °C (lit.) | [Boiling point ]
324.47°C (rough estimate) | [density ]
1.1596 (rough estimate) | [refractive index ]
1.5012 (estimate) | [storage temp. ]
0-6°C | [form ]
Crystals or Crystalline Powder | [pka]
15.01±0.30(Predicted) | [color ]
White to yellow | [Detection Methods]
HPLC,NMR | [BRN ]
146395 | [InChI]
InChI=1S/C11H11NO2/c1-2-14-11(13)10-7-8-5-3-4-6-9(8)12-10/h3-7,12H,2H2,1H3 | [InChIKey]
QQXQAEWRSVZPJM-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=CC=C2)C=C1C(OCC)=O | [CAS DataBase Reference]
3770-50-1(CAS DataBase Reference) | [NIST Chemistry Reference]
1H-indole-2-carboxylic acid, ethyl ester(3770-50-1) |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Keep Cold | [HazardClass ]
IRRITANT | [HS Code ]
29339990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellow crystals or crystalline powder | [Uses]
2-Ethoxycarbonylindole is a building block that has been used as a reactant for the preparation of pyridazinoindole derivatives that have antimicrobial activities. | [Uses]
Reactant for preparation of:• ;CRTH2 receptor antagonists1• ;Indoleamine 2,3-dioxygenase (IDO) inhibitors2• ;Cannabinoid CB1 receptor antagonists3• ;Inhibitors of Human Reticulocyte 15-Lipoxygenase-14• ;N-(benzoylphenyl)-1H-indole-2-carboxamides as potent antihypertriglyceridemic agents5• ;A antiproliferative agent against human leukemia K562 cells6• ;Inhibitors of p38 MAP kinase7• ;Acetolactate synthase inhibitors8 | [Uses]
Reactant for preparation of:CRTH2 receptor antagonists;Indoleamine 2,3-dioxygenase (IDO) inhibitors;Cannabinoid CB1 receptor antagonists; Inhibitors of Human Reticulocyte 15-Lipoxygenase-1;N-(benzoylphenyl)-1H-indole-2-carboxamides as potent antihypertriglyceridemic agents;A antiproliferative agent against human leukemia K562 cells;Inhibitors of p38 MAP kinase; Acetolactate synthase inhibitors. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 39, p. 1152, 1991 DOI: 10.1248/cpb.39.1152 |
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