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625-53-6

625-53-6 Structure

625-53-6 Structure
IdentificationMore
[Name]

ETHYLTHIOUREA
[CAS]

625-53-6
[Synonyms]

1-ETHYL-2-THIOUREA
1-ETHYLTHIOUREA
ETHYLTHIOUREA
N-ETHYL-2-THIOUREA
N-ETHYLTHIOUREA
N-ETHYLTHIOUREA, POLYMER-BOUND
1-ethyl-2-thio-ure
ethyl-2-thiourea
Ethylthiourea,99%
Thiourea, ethyl-
[EINECS(EC#)]

210-899-3
[Molecular Formula]

C3H8N2S
[MDL Number]

MFCD00004939
[Molecular Weight]

104.17
[MOL File]

625-53-6.mol
Chemical PropertiesBack Directory
[Melting point ]

108-110 °C(lit.)
[Boiling point ]

132 °C
[density ]

1.055 (estimate)
[refractive index ]

1.5500 (estimate)
[storage temp. ]

Store at RT
[solubility ]

methanol: soluble25mg/mL, clear, colorless
[pka]

14.97±0.29(Predicted)
[Water Solubility ]

Soluble in water (24g/L).
[BRN ]

1699551
[InChIKey]

GMEHFXXZSWDEDB-UHFFFAOYSA-N
[CAS DataBase Reference]

625-53-6(CAS DataBase Reference)
[EPA Substance Registry System]

Ethylthiourea (625-53-6)
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

R25:Toxic if swallowed.
[Safety Statements ]

S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 2811 6.1/PG 3
[WGK Germany ]

3
[RTECS ]

YT3700000
[TSCA ]

Yes
[HazardClass ]

6.1
[PackingGroup ]

III
[Safety Profile]

Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.
[Hazardous Substances Data]

625-53-6(Hazardous Substances Data)
[Toxicity]

mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981.
Raw materials And Preparation ProductsBack Directory
[Preparation Products]

Guanidineacetic acid-->N-ethyl-5-methylthiazol-2-amine
Hazard InformationBack Directory
[Uses]

N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides
[Definition]

ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea.
[General Description]

N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.
[Biological Activity]

Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).
[Purification Methods]

Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]
Spectrum DetailBack Directory
[Spectrum Detail]

ETHYLTHIOUREA(625-53-6)MS
ETHYLTHIOUREA(625-53-6)1HNMR
ETHYLTHIOUREA(625-53-6)IR1
ETHYLTHIOUREA(625-53-6)IR2
ETHYLTHIOUREA(625-53-6)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

N-Ethylthiourea, 99%(625-53-6)
[Sigma Aldrich]

625-53-6(sigmaaldrich)
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