1-羟基咪达唑仑
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- CAS号:
- 59468-90-5
- 英文名:
- 1'-HYDROXYMIDAZOLAM
- 英文别名:
- α-Hydroxymidazolam;ALPHA-HYDROXYMIDAZOLAM;1-Oh-mdz;RO 21-6347;A-HYDROXYMIDAZOLAM;1Hydroxymidazolame;1'-HYDROXYMIDAZOLAM;1-HYDROXY MIDAZOLAM;1'-Hydroxymidazolam;Midazolam Impurity 1
- 中文名:
- 1-羟基咪达唑仑
- 中文别名:
- 咪达唑仑杂质1;1'-羟咪唑仑;1'-羟基咪唑胺;Α-羟基咪达唑仑;1-羟基咪达唑仑;咪达唑仑杂质12;1′-羟基咪唑安定;A-羟基咪达唑仑 标准品;咪达唑仑杂质1 (不能提供);1-羟基咪达唑仑/咪达唑仑杂质12
- CBNumber:
- CB3147586
- 分子式:
- C18H13ClFN3O
- 分子量:
- 341.77
- MOL File:
- 59468-90-5.mol
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1-羟基咪达唑仑化学性质
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熔点:
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264-266oC
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沸点:
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540.6±60.0 °C(Predicted)
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密度:
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1.43±0.1 g/cm3(Predicted)
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闪点:
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9℃
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储存条件:
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2-8°C
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溶解度:
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DMF: 2 mg/ml; DMSO: 1 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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13.59±0.10(Predicted)
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颜色:
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white or off-white
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1-羟基咪达唑仑性质、用途与生产工艺
1'-Hydroxymidazolam 是 Midazolam 的主要活性代谢产物，并且是一种神经元抑制剂。1'-Hydroxymidazolam 能够抑制神经元活性并增加 Midazolam 的作用。
1'-Hydroxymidazolam (5 nM-1 µM) induces a significant inhibition of the action potential firing rate at concentrations of 100 nM or higher and causes a steady increase in the depression of network activity with increasing concentrations of up to 1 µM in neocortical slice cultures from wild-type mice.
1-羟基咪达唑仑
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-118645 | 1-羟基咪达唑仑
1'-Hydroxymidazolam | 59468-90-5 | 1 mg | 4500元 |
| 2023/10/26 | HY-118645 | 1-羟基咪达唑仑
1'-Hydroxymidazolam | 59468-90-5 | 5mg | 12000元 |
1-羟基咪达唑仑
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59468-90-5, 1-羟基咪达唑仑 相关搜索:
- Metabolites
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Heterocycles
- Aromatics
- 1 ADME产品-体外代谢标准品
- 抑制剂
- 试剂盒-细胞分析试剂盒
- 生化试剂
- 其他兽药标准品
- 1-羟基咪达唑仑/咪达唑仑杂质12
- 1'-羟基咪唑胺
- 1'-HYDROXY MIDAZOLAM(CYP3A4)
- 1′-羟基咪唑安定
- Α-HYDROXYMIDAZOLAM
- 咪达唑仑杂质12
- 咪达唑仑杂质1 (不能提供)
- 咪达唑仑杂质1
- A-羟基咪达唑仑 标准品
- 1'-羟咪唑仑
- Α-羟基咪达唑仑
- 1-羟基咪达唑仑
- 59468-90-5
- 1'-Hydroxymidazolam
- α-Hydroxymidazolam solution
- α-Hydroxymidazolam
- ALPHA-HYDROXYMIDAZOLAM
- 1'-hydroxy Midazolam (Ro 21-6347)
- 1’-Hydroxy Midazolam (1.0 mg/mL in methanol)
- Midazolam Impurity 12
- CYP3A4 metabolite of Midazolam
- Midazolam Impurity 1
- α-Hydroxymidazolam solution
- 1'-Hydroxy MidazolaM (100 μg/ML in Methanol)
- 1-Oh-mdz
- 8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol
- 1-hydroxymethylmidazolam
- 4H-Imidazo1,5-a1,4benzodiazepine-1-methanol, 8-chloro-6-(2-fluorophenyl)-
- alpha-Hydroxymidazolame
- 1Hydroxymidazolame
- 1'-HYDROXYMIDAZOLAM
- 1-HYDROXY MIDAZOLAM
- RO 21-6347
- A-HYDROXYMIDAZOLAM
- 8-CHLORO-6-(2-FLUOROPHENYL)-1-HYDROXYMETHYL-4H-IMIDAZO[1,5A][1,4]BENZODIAZEPINE