EGFR INHIBITOR
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- CAS号:
- 879127-07-8
- 英文名:
- EGFR inhibitor
- 英文别名:
- EGFR-IN-12;EGFR inhibitor;EGFR inhibitor 324674;EGFR inhibitor(YUN27078);EGFR Inhibitor [879127-07-8];EGFR Inhibitor [879127-07-8] - EGFR Inhibitor 324674;N-(3-((6-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)cyclopropanecarboxamide;CyclopropanecarboxaMide, N-[3-[[6-[[3-(trifluoroMethyl)phenyl]aMino]-4-pyriMidinyl]aMino]phenyl]-;EGFR,EGFRIN12,autophosphorylation,anti-proliferation,4,6-disubstituted,antitumor,kinases,Epidermal growth factor receptor,inhibit,EGFR IN 12,AKT,pyrimidine,ErbB-1,Apoptosis,Inhibitor,HER1,Tyrosine
- 中文名:
- EGFR INHIBITOR
- 中文别名:
- 化合物EGFR INHIBITOR;优选]EGFR INHIBITOR;N-(3-((6-((3-(三氟甲基)苯基)氨基)嘧啶-4-基)氨基)苯基)环丙酰胺
- CBNumber:
- CB32597567
- 分子式:
- C21H18F3N5O
- 分子量:
- 413.4
- MOL File:
- 879127-07-8.mol
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EGFR INHIBITOR化学性质
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沸点:
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605.9±55.0 °C(Predicted)
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密度:
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1.456±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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insoluble in H2O; insoluble in EtOH; ≥60.7 mg/mL in DMSO
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形态:
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crystalline solid
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酸度系数(pKa):
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14.50±0.70(Predicted)
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EGFR INHIBITOR性质、用途与生产工艺
EGFR inhibitor 是一种可透过细胞的4,6-二取代嘧啶化合物，是一种具有高度选择性的 EGFR kinase 的抑制剂，其IC50值为21 nM。EGFR inhibitor 可直接使 microtubules 解聚，可作为研究EGFR途径和微管动力学的化学探针。
| Target | Value |
Microtubules
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EGFR
(Cell-free assay)
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21 nM
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EGFR INHIBITOR
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-17499 | EGFR-IN-12 | | 1 mg | 754元 |
| 2024/04/30 | HY-17499 | EGFR INHIBITOR
EGFR-IN-12 | 879127-07-8 | 5mg | 1800元 |
879127-07-8, EGFR INHIBITOR 相关搜索:
- A EGFR tyrosine kinase inhibitor.
- 合成有机化合物配体
- 抑制剂
- 优选]EGFR INHIBITOR
- N-(3-((6-((3-(三氟甲基)苯基)氨基)嘧啶-4-基)氨基)苯基)环丙酰胺
- 化合物EGFR INHIBITOR
- 879127-07-8
- EGFR,EGFRIN12,autophosphorylation,anti-proliferation,4,6-disubstituted,antitumor,kinases,Epidermal growth factor receptor,inhibit,EGFR IN 12,AKT,pyrimidine,ErbB-1,Apoptosis,Inhibitor,HER1,Tyrosine
- N-(3-((6-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)cyclopropanecarboxamide
- EGFR Inhibitor [879127-07-8] - EGFR Inhibitor 324674
- EGFR inhibitor(YUN27078)
- EGFR inhibitor 324674
- EGFR-IN-12
- EGFR Inhibitor [879127-07-8]
- CyclopropanecarboxaMide, N-[3-[[6-[[3-(trifluoroMethyl)phenyl]aMino]-4-pyriMidinyl]aMino]phenyl]-
- EGFR inhibitor