L-半胱亚磺酸
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- CAS号:
- 1115-65-7
- 英文名:
- L-CYSTEINESULFINIC ACID
- 英文别名:
- 3-Sulfinoalanine;Sulfino-D-alanine;3-sulphino-L-alanine;L-Alanine, 3-sulfino-;L-CYSTEINESULFINIC ACID;Carbocysteine Impurity 5;L-cysteine sulphinic acid;CYSTEINE(L) SULFINIC ACID;Acetylcysteine Impurity 26;2-amino-3-sulfino-propanoic acid
- 中文名:
- L-半胱亚磺酸
- 中文别名:
- L-半胱亚磺酸;L-半系八碱酸;L-半胱氨酸亚磺酸;乙酰半胱氨酸杂质26;乙酰半胱氨酸杂质25;3-亚磺基-L-丙氨酸;Α-氨基-Β-亚磺基丙酸
- CBNumber:
- CB3779811
- 分子式:
- C3H7NO4S
- 分子量:
- 153.16
- MOL File:
- 1115-65-7.mol
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L-半胱亚磺酸化学性质
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熔点:
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>130°C (dec.)
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沸点:
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492.8±55.0 °C(Predicted)
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密度:
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1.828±0.06 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Aqueous Acid (Slightly, Sonicated), Water (Slightly)
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酸度系数(pKa):
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2.30±0.10(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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水溶解性:
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Soluble to 100 mM in water
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L-半胱亚磺酸性质、用途与生产工艺
L-Cysteinesulfinic acid 是一种有效的代谢型谷氨酸受体 (mGluRs) 激动剂，作用于mGluR1，mGluR5，mGluR2，mGluR4，mGluR6 和 mGluR8，pEC50 分别为 3.92，4.6，3.9，2.7，4.0，和 3.94。
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mGluR1
3.92 (pEC
50
)
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mGluR2
3.9 (pEC
50
)
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mGluR4
2.7 (pEC
50
)
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mGluR5
4.6 (pEC
50
)
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mGluR6
4.0 (pEC
50
)
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mGluR8
3.94 (pEC
50
)
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Human Endogenous Metabolite
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L-Cysteinesulfinic acid is an endogenous agonist of a metabotropic receptor coupled to stimulation of phospholipase D (PLD) activity. L-CSA is an endogenous agonist of the PLD-coupled metabotropic excitatory amino acids (EAA) receptor. L-CSA selectively activates the PLD-coupled receptor. 1 mM L-CSA induces a significant increase in PLD activity in hippocampal slices, whereas 1 mM concentrations of L-glutamate, L-aspartate, and L-HCA are without effect. L-CSA elicits a dose-dependent increase in PLD activity in rat hippocampal slices in the presence of iGluR antagonists, with an approximate EC
50
of 500 uM. The PLD response induced by 1 mM L-CSA is not significantly decreased in the presence of 1 uM tetrodotoxin, suggesting that this response is not dependent upon L-CSA-induced increases
in cell firing.
L-半胱亚磺酸
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-100804 | L-Cysteinesulfinic acid | | 5 mg | 375元 |
| 2024/04/30 | HY-100804 | L-Cysteinesulfinic acid | | 10 mg | 600元 |
1115-65-7, L-半胱亚磺酸 相关搜索:
- Others
- Metabolites and Cofactors on the Metabolic Pathways Chart
- Metabolic Pathways
- Excitatory Amino Acids
- Amino AcidNeurotransmitters
- 合成有机化合物配体
- BioChemical
- Amino Acid
- Metabolic Pathways
- Metabolites and Cofactors on the Metabolic Pathways Chart
- Metabolomics
- C3H6NO4S
- C3H7CO4S
- C3H7NO4S
- 乙酰半胱氨酸杂质26
- L-半系八碱酸
- 乙酰半胱氨酸杂质25
- Α-氨基-Β-亚磺基丙酸
- L-半胱氨酸亚磺酸
- 3-亚磺基-L-丙氨酸
- L-半胱亚磺酸
- 1115-65-7
- 3-Sulfinoalanine
- Sulfino-D-alanine
- Acetylcysteine Impurity 26
- L-Alanine, 3-sulfino-
- Carbocysteine Impurity 5
- L-CYSTEINESULFINIC ACID 1-HYDRATE
- L-cysteine sulphinic acid
- 3-sulphino-L-alanine
- 2-amino-3-sulfino-propanoic acid
- CYSTEINE(L) SULFINIC ACID
- L-CYSTEINESULFINIC ACID