吲哚霉素
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- CAS号:
- 21200-24-8
- 英文名:
- (-)-Indolmycin
- 英文别名:
- Pa-155-A;indolomycin;(-)-INDOLMYCIN;(S)-5-[(1R)-1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone;[5S,(-)]-5-[(R)-1-(1H-Indol-3-yl)ethyl]-2-methylamino-2-oxazolin-4-one;4(5H)-Oxazolone, 5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-, (5S)-
- 中文名:
- 吲哚霉素
- 中文别名:
- 吲哚霉素
- CBNumber:
- CB62347060
- 分子式:
- C14H15N3O2
- 分子量:
- 257.29
- MOL File:
- 21200-24-8.mol
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吲哚霉素化学性质
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熔点:
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209-210°
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比旋光度:
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D25 -214° (c = 2 in methanol)
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沸点:
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420.8±37.0 °C(Predicted)
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密度:
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1.36±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C, protect from light
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溶解度:
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Soluble in ethanol;methanol;DMSO;dimethyl formamide
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形态:
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powder
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酸度系数(pKa):
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16.65±0.30(Predicted)
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颜色:
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white
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吲哚霉素性质、用途与生产工艺
Indolmycin (TAK-083) 是一种抗生素，是原核生物色氨酸-tRNA 连接酶 (TrpS) 的竞争性抑制剂。Indolmycin (TAK-083) 具有抗菌和抗病毒活性。
Indolmycin was bacteriostatic and demonstrated good activity against MSSA (methicillinsusceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycinintermediate S. aureus), including strains resistant to mupirocin or fusidic acid. Indolmycin MICs for 20 strains ranged from 8 to 32 mg/L, whereas a
single strain exhibited high-level resistance (MIC 128 mg/L).
吲哚霉素
上下游产品信息
上游原料
下游产品
21200-24-8, 吲哚霉素 相关搜索:
- 生化试剂
- 微生物代谢物
- 吲哚霉素
- 21200-24-8
- indolomycin
- 4(5H)-Oxazolone, 5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-, (5S)-
- (-)-INDOLMYCIN
- Pa-155-A
- [5S,(-)]-5-[(R)-1-(1H-Indol-3-yl)ethyl]-2-methylamino-2-oxazolin-4-one
- (S)-5-[(1R)-1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone