螺内酯EP杂质C
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- CAS号:
- 976-70-5
- 英文名:
- 3-oxopregn-4-ene-21,17alpha-carbolactone
- 英文别名:
- Aldone;SC-5233;6,7-Dihydrocanrenone;Spironolactone Impurity C;20-spirox-4-ene-3,20-dione;Spironolactone EP Impurity C;3-oxopregn-4-ene-21,17alpha-carbolactone;17alpha-(2-carboxyethyl)testosterone gamma-lactone;Spironolactone Impurity 3（Spironolactone EP Impurity C）;(17R)-3-Oxo-17-hydroxypregn-4-ene-21-carboxylic acid γ-lactone
- 中文名:
- 螺内酯EP杂质C
- 中文别名:
- 螺内酯杂质C;螺内酯EP杂质C;安体舒通EP杂质C;螺内酯杂质C (EP/BP);螺内酯相关化合物C(USP);螺内酯(安体舒通)EP杂质C;螺内酯杂质3(螺内酯EP杂质C);SPIRONOLACTONE EP杂质 C;17Β-羟基-3-氧代孕甾-4-烯-21-羧酸-Γ-内酯;(2'R,8R,9S,10R,13S,14S)-10,13-二甲基-1,6,7,8,9,10,11,12,13,14,15,16-十二氢-3'H-螺环[A]菲-17,2'-呋喃]-3,5'(2H,4'H)-二酮 (螺内酯杂质)
- CBNumber:
- CB7888197
- 分子式:
- C22H30O3
- 分子量:
- 342.48
- MOL File:
- 976-70-5.mol
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螺内酯EP杂质C化学性质
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熔点:
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156-159 °C
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沸点:
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522.8±50.0 °C(Predicted)
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密度:
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1.17±0.1 g/cm3(Predicted)
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储存条件:
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Hygroscopic, Refrigerator, Under inert atmosphere
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溶解度:
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Chloroform (Slightly), Methanol (Slightly)
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形态:
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Solid
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颜色:
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White to Pale Yellow
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水溶解性:
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20.4mg/L at 20℃
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稳定性:
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Hygroscopic
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螺内酯EP杂质C性质、用途与生产工艺
化学性质
产品为结晶化合物。
用途
安体舒通的中间体。
生产方法
可用17α-乙炔基-3β,17β-二羟基雄甾-5-烯与甲基碘化镁反应，然后乙炔基上羧化、水解，生成3β,17β-二羟基雄甾-5-烯-17α-丙炔酸，继而经成盐、催化氢化得3β,17β-二羟基雄甾-5-烯-17α-丙酸钾，最后经内酯化并氧化（3-位羟基）制得该品。
螺内酯EP杂质C
上下游产品信息
上游原料
下游产品
976-70-5, 螺内酯EP杂质C 相关搜索:
- 杂质对照品
- 螺内酯杂质3(螺内酯EP杂质C)
- (2'R,8R,9S,10R,13S,14S)-10,13-二甲基-1,6,7,8,9,10,11,12,13,14,15,16-十二氢-3'H-螺环[A]菲-17,2'-呋喃]-3,5'(2H,4'H)-二酮 (螺内酯杂质)
- 螺内酯杂质C
- 螺内酯(安体舒通)EP杂质C
- SPIRONOLACTONE EP杂质 C
- 安体舒通EP杂质C
- 螺内酯杂质C (EP/BP)
- 螺内酯相关化合物C(USP)
- 螺内酯EP杂质C
- 17Β-羟基-3-氧代孕甾-4-烯-21-羧酸-Γ-内酯
- 976-70-5
- (2'R,8R,9S,10R,13S,14S)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione (Spironolactone Impurity)
- (2′R)-3′,4′-dihydro-5′H-spiro[androst-4-ene-17,2′-furan]-3,5′-dione (aldone)
- Aldone
- Spironolactone Related Compound C ((2''R)-3'',4''-Dihydro-5''H-spiro[androst-4-ene-17,2''-furan]-3,5''-di (1619039)
- Spironolactone EP impurity CQ: What is
Spironolactone EP impurity C Q: What is the CAS Number of
Spironolactone EP impurity C Q: What is the storage condition of
Spironolactone EP impurity C Q: What are the applications of
Spironolactone EP impurity C
- Spironolactone Impurity C
- (2'R,8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione
- Pregn-4-ene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, (17α)-
- Spironolactone Impurity 3（Spironolactone EP Impurity C）
- 10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spi ro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione
- (8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
- Spironolactone EP Impurity C
- Spironolactone EP IMpurity C: (2'R)-3', 4'-Dihydro-5'H-Spiro[androst-4-ene-17, 2'-furan]-3, 5&
- 17-hydroxy-3-oxo-17-alpha-pregn-4-ene-21-carboxylic aci gamma-lactone
- 3-oxopregn-4-ene-21,17alpha-carbolactone
- SC-5233
- 6,7-Dihydrocanrenone
- (17R)-3-Oxo-17-hydroxypregn-4-ene-21-carboxylic acid γ-lactone
- (17R)-17-Hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone
- 17alpha-(2-carboxyethyl)testosterone gamma-lactone
- 3-(3-oxo-17-beta-hydroxy-4-androsten-17-alpha-yl)propionic acid gamma-lactone
- 20-spirox-4-ene-3,20-dione