盐酸呋喃硫胺
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- CAS号:
- 2105-43-3
- 英文名:
- FURSULTIMINE HYDROCHLORIDE
- 英文别名:
- TTFD hydrochloride;FURSULTIMINE HYDROCHLORIDE;FURSULTIMINE HYDROCHLORIDE USP/EP/BP;Fursultiamine Hydrochloride
（mixture of isomers）;Thiamin tetrahydrofurfuryl disulfide hydrochloride;Thiamine tetrahydrofurfuryl disulfide hydrochloride;N-(4-Amino-2-methylpyrimidin-5-ylmethyl)-N-{4-hydroxy-1-methyl-2-[(RS)-tetrahydrofuran-2-ylmethyldisulfanyl]but-1-en-1-y;N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]but-1-en-1-yl]formamide monohydrochloride;N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]but-1-en-1-yl]formamide monohydrochloride;Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-, monohydrochloride (8CI)
- 中文名:
- 盐酸呋喃硫胺
- 中文别名:
- 盐酸呋喃舒敏;盐酸呋喃磺胺;盐酸呋喃硫胺;呋喃硫胺及盐酸呋喃硫胺;N-[(4-氨基-2-甲基-5-嘧啶基)甲基]-N- [4-羟基-1-甲基-2-[[(四氢-2-呋喃基)甲基]二硫]-1-丁烯-1-基]-甲酰胺盐酸盐
- CBNumber:
- CB8419073
- 分子式:
- C17H27ClN4O3S2
- 分子量:
- 435
- MOL File:
- 2105-43-3.mol
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盐酸呋喃硫胺化学性质
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熔点:
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160 °C (decomp)
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溶解度:
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DMSO (Slightly, Heated), Methanol (Slightly)
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形态:
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Solid
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颜色:
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White to Off-White
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盐酸呋喃硫胺性质、用途与生产工艺
盐酸呋喃硫胺为白色或微黄色结晶性粉末，无臭或略有类似蒜臭。在水中或丙酮中微溶；在甲醇、乙醇或氯仿中易溶；在苯或乙醚中几乎不溶。熔点130-136℃ (分解)。
盐酸呋喃硫胺适用于维生素B1的脚气病或Wernicke脑病的治疗，亦可用于维生素B1缺乏引起的周围神经炎、消化不良等的辅助治疗。
盐酸呋喃硫胺是维生素 B1的新型衍生物，在体内迅速转化为活性硫胺，不为体内硫胺酶分解，对组织亲和力强，脏器浓度高，血中浓度高，维持时间长，具有高效、长效、低毒的特性。
盐酸呋喃硫胺偶见头昏、乏力、恶心、呕吐，停药后即消失；注射局部偶有硬包块，热敷或停药后可渐消失。
盐酸呋喃硫胺
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2105-43-3, 盐酸呋喃硫胺 相关搜索:
- 有机中间体
- C17H27ClN4O3S2
- C17H26N4O3S2HCl
- 盐酸呋喃舒敏
- 盐酸呋喃磺胺
- N-[(4-氨基-2-甲基-5-嘧啶基)甲基]-N- [4-羟基-1-甲基-2-[[(四氢-2-呋喃基)甲基]二硫]-1-丁烯-1-基]-甲酰胺盐酸盐
- 盐酸呋喃硫胺
- 呋喃硫胺及盐酸呋喃硫胺
- 2105-43-3
- N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]but-1-en-1-yl]formamide monohydrochloride
- FURSULTIMINE HYDROCHLORIDE USP/EP/BP
- Fursultiamine Hydrochloride
（mixture of isomers）
- TTFD hydrochloride
- Thiamin tetrahydrofurfuryl disulfide hydrochloride
- Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-, monohydrochloride
- Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-, monohydrochloride (8CI)
- Thiamine tetrahydrofurfuryl disulfide hydrochloride
- N-(4-Amino-2-methylpyrimidin-5-ylmethyl)-N-{4-hydroxy-1-methyl-2-[(RS)-tetrahydrofuran-2-ylmethyldisulfanyl]but-1-en-1-y
- N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]but-1-en-1-yl]formamide monohydrochloride
- FURSULTIMINE HYDROCHLORIDE