佐剂肽
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- CAS号:
- 53678-77-6
- 英文名:
- Muramyl Dipeptide
- 英文别名:
- MDP;n-acetylmuramyl-l-alanyl-d-isoglutamine hydrate;HRDP;DPEP1;L-18-MDP;Aids000724;Aids-000724;Dipeptidase 1;ADJUVANT PEPTIDE;MURAMYL DIPEPTIDE
- 中文名:
- 佐剂肽
- 中文别名:
- 佐剂肽;胞壁酰二肽;胞壁酰二肽MDP;胞壁酰二肽(佐剂肽);MURAMYL DIPEPTIDE,佐剂肽;N-乙酰胞壁酰-L-丙-D-异谷氨酰胺水合物;N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺水合物;N-乙酰胞壁酰基-L-丙氨酰基-D-异谷氨酰胺 水合物;N-乙酰胞壁酰基-L-丙氨酰基-D-异谷氨酰胺 水合物
- CBNumber:
- CB9237089
- 分子式:
- C19H32N4O11
- 分子量:
- 492.48
- MOL File:
- 53678-77-6.mol
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佐剂肽化学性质
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比旋光度:
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D25 +44° (acetic acid)
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沸点:
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1071.8±65.0 °C(Predicted)
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密度:
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1.390±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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H2O: 10 mg/mL, clear, colorless
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酸度系数(pKa):
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4.44±0.10(Predicted)
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形态:
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buffered aqueous solution
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Merck:
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13,6329
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BRN:
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4220745
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CAS 数据库:
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53678-77-6(CAS DataBase Reference)
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佐剂肽性质、用途与生产工艺
佐剂肽是指一种通过诱发、加强和/或促进针对抗原的免疫反应来促进或调节抗原功能而作为功能性组分(组合物中)的肽。
佐剂肽主要用于医药、化工领域。
Muramyl dipeptide (MDP) 是肽聚糖的共有结构单元。Muramyl dipeptide 通过诱导 Runx2 来诱导 bone formation。
Muramyl dipeptide (0.1-10 µg/mL; 24 hours) increases protein expression of Runx2 in a dose-dependent manner.
Muramyl dipeptide (0.1-10 µg/mL; 6 hours) increases mRNA levels of Runx2 in a dose-dependent manner.
Western Blot Analysis
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Cell Line:
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MC3T3-E1 cells
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Concentration:
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0.1, 1, 10 µg/mL
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Incubation Time:
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24 hours
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Result:
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Increased protein expression of Runx2 in a dose-dependent manner.
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RT-PCR
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Cell Line:
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MC3T3-E1 cells
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Concentration:
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0.1, 1, 10 µg/mL
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Incubation Time:
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6 hours
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Result:
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Increases mRNA levels of Runx2 in a dose-dependent manner.
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Muramyl dipeptide (1.25 mg/kg; i.p.; twice) alleviates bone loss induced by osteoporosis.
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Animal Model:
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RANKL-induced osteoporosis model (Five-week-old C57BL/6 mice)
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Dosage:
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1.25 mg/kg
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Administration:
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i.p.; twice (RANKL-induced osteoporosis for 3 weeks and euthanized at 4 weeks)
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Result:
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Significantly enhanced the trabecular bone volume (BV/TV) and trabecular number (Tb.N).
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佐剂肽
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-127090 | 佐剂肽
Muramyl dipeptide | 53678-77-6 | 1mg | 914元 |
| 2024/04/30 | S9709 | 佐剂肽
Muramyl dipeptide | 53678-77-6 | 5mg | 2203.4元 |
佐剂肽
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53678-77-6, 佐剂肽 相关搜索:
- 生化试剂
- 多肽
- 原料
- 精细化工
- Tripeptides
- BioChemical
- Amino Acids and Peptides
- Other Peptides
- Peptides
- Dipeptides and Tripeptides
- Biochemicals and Reagents
- C19H32N4O11xH2O
- C19H32N4O11
- N-乙酰胞壁酰基-L-丙氨酰基-D-异谷氨酰胺 水合物
- 胞壁酰二肽MDP
- MURAMYL DIPEPTIDE,佐剂肽
- 胞壁酰二肽(佐剂肽)
- N-乙酰胞壁酰基-L-丙氨酰基-D-异谷氨酰胺 水合物
- 佐剂肽
- N-乙酰胞壁酰-L-丙-D-异谷氨酰胺水合物
- N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺水合物
- 胞壁酰二肽
- 53678-77-6
- D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-
- n-acetylmuramyl-l-alanyl-d-isoglutamine hydrate
- MDP
- Ac-muramyl-Ala-D-Glu-NH2 (G-1055.0005)
- Muramyl Dipeptide USP/EP/BP
- Muramoyl dipeptide
- Recombinant Human DPEP1 Protein, His Tag
- N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate >=98% (TLC)
- D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-
- Muramyl dipeptide (MDP)
- N-Acetylmuramoyl-L-alanyl-D-α-glutamine
- Ac-muramyl-Ala-D-Glu-NH
- N-Acetylmuramyl-L-alanyl-D-isoglnamine hydrate
- ADJUVANT PEPTIDE
- AC-MURAMYL-ALA-D-ISOGLUTAMINE
- AC-MURAMYL-ALA-D-ISOGLN-OH
- AC-MURAMYL-ALA-D-GLU-NH2
- AC-MURAMYL-ALA-D-GLN
- (4R)-4-{[(2S)-2-{[(2R)-2-{[(3R,4R,5S,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid
- N-ACETYLMURAMYLL-ALANYL-D-ISOGLUTAMI
- DPEP1
- Dipeptidase 1
- Dehydropeptidase-I
- ANTI-DPEP1 (N-TERM) antibody produced in rabbit
- HRDP
- Dipeptidase 1 (renal)
- Ac-MuraMyl-Ala-D-Isogln-OH, MDP, MuraMyl Dipeptide
- D-.alpha.-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-
- Aids-000724
- Aids000724
- N-Acetylmuramoylalanyl-D-isoglutamine
- N2-[N-(N-Acetylmuramoyl)-L-alanyl]-D-isoglutamine
- N-(N-Acetylmuramoyl)-L-Ala-D-αGlu-NH2
- L-18-MDP
- Adjuvant Peptide, Muramyl dipeptide