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Ciprofloxacin HCl

Ciprofloxacin HCl Struktur
93107-08-5
CAS-Nr.
93107-08-5
Englisch Name:
Ciprofloxacin HCl
Synonyma:
CIPROFLOXACIN HYDROCHLORIDE;1-Cyclopropyl-6-fluoro;1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride;Cyproxan;BAY-o-9867;CIPROFLOXACIN HCL;Bay-09867 (hydrochloride);Clprofloxacin hydrochloride;Ciprofloxacin hydrochloride CAS 93107-08-5
CBNumber:
CB02130396
Summenformel:
C17H18FN3O3.HCl
Molgewicht:
367.8
MOL-Datei:
93107-08-5.mol
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Ciprofloxacin HCl Eigenschaften

Schmelzpunkt:
>300 ºC
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic
Aggregatzustand
crystalline solid
BCS Class
3
InChI
InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N
SMILES
O=C(O)C1C(=O)C2=CC(=C(C=C2N(C2CC2)C=1)N1CCNCC1)F.[H]Cl
CAS Datenbank
93107-08-5
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 24/25
HS Code  29339900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Ciprofloxacin HCl Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-bacterial

Trademarks

Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).

Synthese

The preparation method of ciprofloxacin HCl, its step is as follows:
a) cyclopropyl carboxylic acid is added in the organic solvent, and the adding piperazine, reacted 3～8 hours down as acid binding agent with alkali at 60～120 ℃, the monitoring cyclopropyl carboxylic acid is residual less than 2% o'clock termination reaction, stirring is cooled to 0～30 ℃, leaves standstill suction filtration;
b) add water and hydrochloric acid in the products therefrom toward a) step, under agitation be warming up to molten clearly, add activated carbon decolorizing, filtered while hot, and transfer filtrate pH to 2～4 with hydrochloric acid, and the cooling crystallization filters, rinsing, and drying makes ciprofloxacin HCl.

Ciprofloxacin HCl Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2,4-Dichloro-5-fluoroacetophenone

Downstream Produkte

Decarboxy Ciprofloxacin Ciprofloxacin

Ciprofloxacin HCl Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 262)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
+8617731987558
 xingjiu@xingjiubiotech.com China 990 58
Hebei ZB Gamay Biological Technology Co.,Ltd
+86-031189171450 +86-15632359451
 chem@zbvet.net China 222 58
Guangzhou Tosun Pharmaceutical Limited
+8618922120635
 sales@toref-standards.com China 1000 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177
 sarah@tnjone.com China 1125 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 6000 58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. 		+86-029-86333380 18829239519
 sales06@tgybio.com China 944 58
Hebei Guanlang Biotechnology Co,.LTD 		+8619930503252
 daisy@crovellbio.com China 5963 58
shandong perfect biotechnology co.ltd 		+86-53169958659; +8618596095638
 sales@sdperfect.com China 294 58
Henan Suikang Pharmaceutical Co.,Ltd. 		+86-18239973690 +86-18239973690
 sales@suikangpharm.com China 186 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21689 55

93107-08-5()Verwandte Suche:

2,6-Dimethyloct-7-en-2-ol Ciprofloxacin hydrochloride ISOPROPYLHYDRAZINE HYDROCHLORIDE Quinclorac Topotecan hydrochloride Isochinolin Piperazine ferulate 2-Piperazin-1-ylethylamin Ciprofloxacin hydrochloride hydrate Ciprofloxacin lactate Ciprofloxacin Norfloxacin Tetracyclin Paracetamol Clindamycin Wasserstoff Fluor fluoro jade
  • 3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1)
  • BAY-o-9867
  • Cyproxan
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride
  • Clprofloxacin hydrochloride
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride
  • CIPROFLOXACIN HCL
  • Ciprofloxacin hydrochloride CAS 93107-08-5
  • Bay-09867 (hydrochloride)
  • Enrofloxacin EP Impurity BQ: What is Enrofloxacin EP Impurity B Q: What is the CAS Number of Enrofloxacin EP Impurity B
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride
  • 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
  • CIPROFLOXACIN HYDROCHLORIDE
  • 1-Cyclopropyl-6-fluoro
  • 93107-08-5
  • C17H19ClFN3O3xHCl
  • Pharmaceutical intermediate
  • 93107-08-5
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