Baicalein
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- CAS-Nr.
- 491-67-8
- Englisch Name:
- Baicalein
- Synonyma:
- 5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one;Baicelein;5,6,7-Trihydroxyflavone,97%;BaicaL;Noroxylin;Baicalein;Baicaleine;Baicalein 98%;Baicalein std.;Baicalein (6CI)
- CBNumber:
- CB0738154
- Summenformel:
- C15H10O5
- Molgewicht:
- 270.24
- MOL-Datei:
- 491-67-8.mol
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Baicalein Eigenschaften
- Schmelzpunkt:
- 256-271 °C (lit.)
- Siedepunkt:
- 373.35°C (rough estimate)
- Dichte
- 1.3280 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Yellow solid
- pka
- 6.31±0.40(Predicted)
- Farbe
- Yellow or yellow-green
- Merck
- 14,942
- BRN
- 272683
- Stabilität:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
- InChIKey
- FXNFHKRTJBSTCS-UHFFFAOYSA-N
- LogP
- 3.310 (est)
- CAS Datenbank
- 491-67-8(CAS DataBase Reference)
Baicalein Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Yellow Crystalline Solid
Verwenden
An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the fl
avonoid component of Nepalese and Sino-Japanese crude drugs.
Definition
ChEBI: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
Allgemeine Beschreibung
Baicalein, a flavonoid, is a xanthine oxidase inhibitor. Anti-inflammatory effects of baicalein in peripheral human leukocytes has been studied.
Biologische Aktivität
Inhibitor of 5- and platelet 12-lipoxygenases (IC 50 values are 9.5 and 0.12 mM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Anti-inflammatory in vivo .
Baicalein Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Baicalein Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 461)Lieferanten
491-67-8()Verwandte Suche:
Riboflavin
THEAFLAVIN
Isoflavone
1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-dien-3,5-dion
Scutellarin
7-Hydroxy-2-phenyl-4-benzopyron
1,3,8-Trihydroxy-6-methylanthrachinon
5,7-Dihydroxy-2-phenyl-4H-benzo[b]pyran-4-on
Flavon
ISOFLAVONES
Wogonoside
Wogonin
SCUTELLAREIN
Baicalin
2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4-benzopyron
6-[4-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyron
5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4-benzopyron
- BAICALEIN(SH)NOW RG GRADE
- Baicalein, monohydrate, 5,6,7-Trihydroxy-2-phenyl-4H-chromen-4-one monohydrate
- Noroxylin
- Baicalein 98%
- 5,6,7-trihydroxy-2-phenyl-4-chromenone hydrate
- Baicaleine
- Baicalein
- 5,6,7-trihydroxy-2-phenyl-chromen-4-one hydrate
- 5,6,7-trihydroxy-2-phenylchromen-4-one hydrate
- 5,6,7-trihydroxy-2-phenyl-chromone hydrate
- Bupleurum distillates
- 4H-1-BENZOPYRAN-4-ONE,5,6,7-TRIHYDROXY-2-PHENYL-
- 5,6,7-TRIHYDROXY-2-PHENYL-(4H)-1-BENZOPYRAN-4-ONE
- 5,6,7-TRIHYDROXYFLAVONE
- BAICALEIN, 98+% BY HPLC
- BAICALEIN4H-1-BENZOPYRAN-4-ONE,5,6,7-TRIHYDROXY-2-PHENYL-,
- Baicalein std.
- Nano Liposomal Baicalein
- Baicalein, 98%, from Scutellaria baicalensis Georgi
- BaicaL
- Baicalein - CAS 491-67-8 - Calbiochem
- Baicalein 491-67-8
- 5,6,7-trihydroxy-2-phenyl-1-benzopyran-4-one hydrate
- Baicalein NanoEmulsion, Water-Soluble Baicalein, Liposomal Baicalein
- Baicalein Standard
- Baicalein USP/EP/BP
- Baicalein (10mM in DMSO)
- Baicalein / Noroxylin
- Scutellaria Baicalensis Extract Baicalein 98%
- 5,6,7-trihydroxy-2-phenylchromen-4-one
- Baicelein
- 5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one
- 5,6,7-Trihydroxyflavone,97%
- Baicalein (6CI)
- 491-67-8
- C15H10O5H2O
- C15H10O5xH2O
- The flavonoid component of Nepalese and Sino-Japanese crude drugs
- Enzyme Inhibitors
- Enzyme Inhibitors by Type
- Enzymes, Inhibitors, and Substrates
- Phytoestrogens
- Other
- Biochemicals and Reagents
- BioChemical
- Chemopreventive Agents
- Cancer Research
- API
- Aromatics
- Heterocycles
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- natural product
- Tri-substituted Flavones
- Inhibitors
