N-(4-Aminobenzoyl)-beta-alanine
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- CAS-Nr.
- 7377-08-4
- Englisch Name:
- N-(4-Aminobenzoyl)-beta-alanine
- Synonyma:
- 7377-08-4-;TIMTEC-BB SBB000472;N-(4-Aminobenzoyl)-;Balsalazide Impurity 2;Balsalazide Impurity 5;Balsalazide Aminobenzoyl;Balsalazide Amino Impurity;N-(4-Aminobenzoyl)--alanine;P-aminobenzoyl-beta-alanine;n-(4-aminobenzoyl)-á-alanine
- CBNumber:
- CB1142204
- Summenformel:
- C10H12N2O3
- Molgewicht:
- 208.21
- MOL-Datei:
- 7377-08-4.mol
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N-(4-Aminobenzoyl)-beta-alanine Eigenschaften
- Schmelzpunkt:
- 152-154 °C(lit.)
- Siedepunkt:
- 347.41°C (rough estimate)
- Dichte
- 1.2420 (rough estimate)
- Dampfdruck
- 0Pa at 20℃
- Brechungsindex
- 1.4830 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Löslichkeit
- DMSO, Methanol (Slightly), Water (Slightly, Heated)
- Aggregatzustand
- Solid
- pka
- 4.36±0.10(Predicted)
- Farbe
- White to Off-White
- InChI
- InChI=1S/C10H12N2O3/c11-8-3-1-7(2-4-8)10(15)12-6-5-9(13)14/h1-4H,5-6,11H2,(H,12,15)(H,13,14)
- InChIKey
- VHAXWROFYVPXMZ-UHFFFAOYSA-N
- SMILES
- C1(C=CC(N)=CC=1)C(=O)NCCC(=O)O
- LogP
- -1.19 at 25℃ and pH7.5
- Oberflächenspannung
- 71.6mN/m at 1g/L and 20℃
- CAS Datenbank
- 7377-08-4(CAS DataBase Reference)
N-(4-Aminobenzoyl)-beta-alanine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
N-(4-Aminobenzoyl)-beta-alanine is a molecule that was identified in the 1960s and has been used extensively for research purposes. It is a prodrug that is converted to salicylic acid in vivo. The drug has been shown to scavenge reactive oxygen species, inhibit the enzyme catalase, and protect against oxidative damage. N-(4-Aminobenzoyl)-beta-alanine also provides protection against colitis by inhibiting peroxide production and preventing oxidative damage of colon cells. This drug is orally active and may have potential clinical applications for patients with catalase deficiency or peroxide-mediated diseases such as colitis.
Chemische Eigenschaften
white to light orange-brown crystalline powder
Verwenden
N-(4-aminobenzoyl)-β-Alanine is a metabolite of BX661A, a therapeutic agent used in the treatment of ulcerative colitis, chemotaxis and reactive oxygen species production in polymorphonuclear leukocy
ctes. Inhibits lipid peroxidation in large intestinal mucosa after mesenteric ischemia/reperfusion.
N-(4-Aminobenzoyl)-beta-alanine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(4-Aminobenzoyl)-beta-alanine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 156)Lieferanten
7377-08-4()Verwandte Suche:
- 3-(4-AMINOBENZOYLAMINO)-PROPIONIC ACID
- N-(4-AMINOBENZOYL)-BETA-ALANINE
- TIMTEC-BB SBB000472
- N-(4-AMINOBENZOYL)-BETA-ALANINE 97%
- N-(4-Aminobenzoyl)-alanine,98%
- N-(4-Aminobenzoyl)--alanine
- N-(4-Aminobenzoyl)-b-alanine
- n-(4-aminobenzoyl)-á-alanine
- N-(P-AMINOBENZOYL)-BETA-ALANINE
- N-(4-AMINOBENZOYL)-SS-ALANINE
- b-Alanine, N-(4-aMinobenzoyl)-
- N-(4-Aminobenzoyl)-
- N-(4-Aminobenzoyl)-beta-alanine,98%
- 3-(4-Aminobenzamido)propionic Acid
- Balsalazide Aminobenzoyl
- N-(4-Aminobenzoyl)-beta-alanine USP/EP/BP
- N-(4-Aminobenzoyl)-β-alanine
- Balsalazide Impurity 2
- N-(4-Aminobenzoyl)-β-alanine>
- Balsalazide Amino Impurity
- Balsalazide Impurity 5
- 3-[[(4-aminophenyl)-oxomethyl]amino]propanoate
- N-(4-Aminobenzoyl)-beta-alanine - 25% aqueous solution
- 7377-08-4-
- P-aminobenzoyl-beta-alanine
- N-(4-Aminobenzoyl)-β-alanine, ≥ 98.0%
- 7377-08-4
- 2000-65-1
- 7377-8-4
- 7737-08-4
- H2NC6H4CONHCH2CH2CO2H
- AMINE
- BALSALAZIDE
