Isosorbidmononitrat
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- CAS-Nr.
- 16051-77-7
- Bezeichnung:
- Isosorbidmononitrat
- Englisch Name:
- Isosorbide 5-mononitrate
- Synonyma:
- ISOSORBIDE MONONITRATE;ISMN;Ismo;IMDUR;5-ismn;Vasotrate;5-ISOSORBIDE MONONITRATE;ELAN;Momt;Coronu
- CBNumber:
- CB3256697
- Summenformel:
- C6H9NO6
- Molgewicht:
- 191.14
- MOL-Datei:
- 16051-77-7.mol
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Isosorbidmononitrat Eigenschaften
- Schmelzpunkt:
- 88-93 °C
- alpha
- 170 º (c=1, EtOH)
- Siedepunkt:
- 326.86°C (rough estimate)
- Dichte
- 1.5784 (rough estimate)
- Brechungsindex
- 145 ° (C=5, H2O)
- storage temp.
- -20°C Freezer
- Löslichkeit
- Undiluted isosorbide mononitrate is freely soluble in water, in acetone, in ethanol (96 per cent) and in methylene chloride. The solubility of the diluted product depends on the diluent and its concentration.
- Aggregatzustand
- Solid
- pka
- 13.09±0.40(Predicted)
- Farbe
- White to Off-White
- Wasserlöslichkeit
- soluble
- Merck
- 5225
- InChIKey
- YWXYYJSYQOXTPL-SLPGGIOYSA-N
- CAS Datenbank
- 16051-77-7(CAS DataBase Reference)
- EPA chemische Informationen
- D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate (16051-77-7)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi-F,Xi,F |
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| R-Sätze: |
36/37/38-11 |
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| S-Sätze: |
37/39-16-15 |
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| RIDADR |
3251 |
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| RTECS-Nr. |
LZ4386500 |
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| HazardClass |
4.1 |
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| HS Code |
2932999000 |
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| Toxizität |
LD50 oral in rat: 2010mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H228 |
Entzündbarer Feststoff. |
Entzündbare Feststoffe |
Kategorie 1 |
Achtung
Warnung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210, P240,P241, P280, P370+P378 |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P240 |
Behälter und zu befüllende Anlage erden. |
| P241 |
Explosionsgeschützte [elektrische/Lüftungs-/ Beleuchtungs-/...] Geräte verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P370+P378 |
Bei Brand: zum Löschen verwenden. |
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Isosorbidmononitrat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R11:Leichtentzündlich.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S15:Vor Hitze schützen.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
Isosorbide 5-Mononitrate is a metabolite of Isosorbide Dinitrate; used as an antianginal.
Allgemeine Beschreibung
Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.
Air & Water Reaktionen
Highly flammable.
Reaktivität anzeigen
The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.
Health Hazard
Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
Brandgefahr
Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
Isosorbidmononitrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Isosorbidmononitrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 402)Lieferanten
16051-77-7(Isosorbidmononitrat)Verwandte Suche:
- IS-5-MN
- ISOSORBIDE 5-MONONITRATE
- ISOSORBIDE 5-NITRATE
- ELANTAN
- ELAN
- CORANGIN
- MONOSORB
- MONOCEDOCARD
- MONOCLAIR
- 1,4:3,6-dianhydro-,5-nitrate,d-glucito
- 1,4:3,6-dianhydro-d-glucito5-nitrate
- 1,4:3,6-dianhydro-d-glucitol5-nitrate
- 1,4:3,6-DIANHYDRO-D-GLUCITOL 5-MONONITRATE
- 6-Nitrooxy-hexahydro-furo[3,2-β]furan-3-ol
- 6-Nitrooxy-hexahydro-furo[3,2-b]furan-3-ol
- D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate
- [(1R,2R,5R,6S)-6-hydroxy-4,8-dioxabicyclo[3.3.0]oct-2-yl] nitrate
- ISOSORBIDE MONO ACETATE
- ahr4698
- bm22-145
- Ososoribide-5-mononitrate
- ISOSORBIDE 5-MONONITRATE, 98.5%
- Corangin,Elan,Elantan,Imdur,Monocedocard,Monoclair,Monosorb
- 1,4:3,6-Dianhydro-D-glucitol mononitrate
- 1,4:3,6-Dianhydro-D-glucitd 5-mononitrate
- 1,4:3,6-Dianhydro-5-O-nitro-D-erythro-hexitol
- IS-5-MN (ISOSORBIDE-5-MONONITRATE
- (3S,3aS,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate
- Isosorbide-5-mononitrate min. 99%
- Isosorbide Mononitrate EP
- Coronu
- Isomonat
- Momt
- Monicor
- Olicard
- [(3R,3aS,6S,6aR)-6-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[2,3-d]furan-3-yl nitrate
- 5-Nitro-1,4,3,6-dianhydro-D-glucitol
- 6-Nitroxoyhexahydrofuro[3,2-b]furan-3-ol
- 8-Nitrooxy-2,6-dioxabicyclo[3.3.0]octan-4-ol
- TY-10368
- Isosorbide mononitrate,contains ~30%(w/w) lactose
- (3R,3aS,6S,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate
- Diluted Isosorbide Mononitrate (750 mg)
- ISOSORBIDE MONONITRATE(ISOSORBIDE-5-MONONITRATE)
- isosorbide 5-mononitrite
- Erlotinib-d17 HCl
- Diluted Isosorbide Mononitrate (50%)
- Isosorbide 5-Mononitrate (1.0 mg/mL in Dimethyl Sulfoxide)
- Isosorbide5-Nitrate>
- Isosorbide mononitrate CRS
- Monoket
- Mononit
- Isosorbide Dinitrate EP Impurity C
- Isosorbide Dinitrate Impurity 3 （Isosorbide Dinitrate EP Impurity C）
- Isosorbide 5-mononitrate USP/EP/BP
- DILUTED ISOSORBIDE MONONITATE 60-70%
- Doravirine 13C,d3
- Isosorbide-5-mononitrateQ: What is
Isosorbide-5-mononitrate Q: What is the CAS Number of
Isosorbide-5-mononitrate Q: What is the storage condition of
Isosorbide-5-mononitrate Q: What are the applications of
Isosorbide-5-mononitrate
