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Toceranib Phosphate

Toceranib Phosphate Struktur
874819-74-6
CAS-Nr.
874819-74-6
Englisch Name:
Toceranib Phosphate
Synonyma:
PHA 291639E;SU11654 phosphate;PHA 291639 phosphate;Toceranib (phosphate);PHA 291639E (phosphate);Toceranib phosphate(SU 11654);Toceranib (PHA 291639) phosphate;5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-n-(2-(pyrrolidin-1-yl)ethyl)-1h-pyrrole-3-carboxamide phosphate;5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide
CBNumber:
CB42563239
Summenformel:
C22H28FN4O6P
Molgewicht:
494.46
MOL-Datei:
874819-74-6.mol
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Toceranib Phosphate Eigenschaften

Schmelzpunkt:
>270°C (dec.)
storage temp. 
-20°C Freezer
Löslichkeit
DMSO (Slightly, Heated)
Aggregatzustand
Solid
Farbe
Yellow to Dark Orange
InChIKey
AOORBROPMMRREB-HBPAQXCTSA-N
SMILES
P(O)(O)(O)=O.C(/C1NC(C)=C(C(=O)NCCN2CCCC2)C=1C)=C1/C(NC2=CC=C(F)C=C/12)=O
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Toceranib Phosphate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ. It is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. It may also have an anti-angiogenic effect.

Verwenden

Toceranib Phosphate is a useful compound in the treatment of chemotherapy-induced diarrhea.

Toceranib Phosphate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Toceranib Phosphate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 99)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Masteam Bio-tech Co., Ltd.
+86-15200345168 +86-15200345168
 bruce.lei@masteam.com CHINA 153 58
Hpets Biotech Company (Chongqing) Co.,ltd
+8613340353813
 info@hanpets.com China 26 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 15954 58
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714
 fandachem@gmail.com China 9339 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070
product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32715 60
Biochempartner 		0086-13720134139
candy@biochempartner.com CHINA 967 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Hubei Ipure Biology Co., Ltd 		+8613367258412
 ada@ipurechemical.com China 10326 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551
info@afinechem.com China 15396 58
  • 1H-Pyrrole-3-carboxaMide, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-N-[2-(1-pyrrolidinyl)ethyl]-, phosphate (1:1)
  • 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide phosphate
  • PHA 291639E
  • Toceranib (phosphate)
  • Toceranib (PHA 291639) phosphate
  • Toceranib phosphate(SU 11654)
  • 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide,phosphoric acid
  • SU11654 phosphate
  • PHA 291639 phosphate
  • (Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-n-(2-(pyrrolidin-1-yl)ethyl)-1h-pyrrole-3-carboxamide phosphate
  • PHA 291639E (phosphate)
  • 1H-Pyrrole-3-carboxamide, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-, phosphate (1:1) (9CI, ACI)
  • 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide
  • 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide
  • 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-Pyrrole-3-carboxamide phosphate (1:1) (9CI ACI)
  • 5-(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl-2,4-dimethyl-N-2-(pyrrolidin-1-yl)ethyl-1H-pyrrol-3-carboxamide phosphate (1:1)
  • 874819-74-6
  • C22H25FN4O2H3PO4
  • C22H25FN4O2H3O4P
  • API
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