3-Morpholinosydnonimine hydrochloride
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- CAS-Nr.
- 16142-27-1
- Englisch Name:
- 3-Morpholinosydnonimine hydrochloride
- Synonyma:
- SIN-1;SIN-1 HCL;LINSIDOMINE;SIN-1 CHLORIDE;LINSIDOMINE HCL;SIN-I HYDROCHLORIDE;SIN-1 HYDROCHLORIDE;MolsidoMine IMpurity A;Linsidomine (chloride);Molsidomine Impurity 7
- CBNumber:
- CB5370997
- Summenformel:
- C6H11ClN4O2
- Molgewicht:
- 206.63
- MOL-Datei:
- 16142-27-1.mol
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3-Morpholinosydnonimine hydrochloride Eigenschaften
- Schmelzpunkt:
- 186 °C
- Dichte
- 1.303 at 20℃
- storage temp.
- -20°C
- Löslichkeit
- Soluble in DMSO (up to 35 mg/ml) or in Water (up to 65 mg/ml)
- Aggregatzustand
- White solid
- Farbe
- White
- Wasserlöslichkeit
- soluble
- Stabilität:
- Stable for 1 year from date of purchase as supplied. Solutions must be prepared fresh and cannot be stored.
- LogP
- -6.28 at 25℃
- CAS Datenbank
- 16142-27-1(CAS DataBase Reference)
3-Morpholinosydnonimine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
As the active metabolite of molsidomine, SIN-
1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
3-Morpholinosydnonimine hydrochloride is a metabolite of the vasodilator Molsidomine (M488002) and is considered to be a peroxynitrite releasing compound. Molsidomine Impurity A.
Indications
Linsidomine (SIN-1) is an active metabolite of the
antianginal drug molsidomine. Its mechanism of action
upon the corpus cavernosum involves the release of nitric
oxide. Injected intracavernosally it can produce penile
erections, but its clinical usefulness has not been
fully established.
Biologische Aktivität
This compound (the active product of the prodrug SIN-10, molsidomine) acts as a vasodilator and inhibitor of platelet aggregation; longer acting than nitroprusside or nitroglycerin. Decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion.
3-Morpholinosydnonimine hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Morpholinosydnonimine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 122)Lieferanten
16142-27-1()Verwandte Suche:
- 3-(4-MORPHOLINYL)-SYDNONE IMINE HYDROCHLORIDE
- 3-MORPHOLINOSYDNOIMINE HCL
- 3-MORPHOLINOSYDNOIMINE HYDROCHLORIDE
- 3-MORPHOLINOSYDNONIMINE CHLORIDE
- 3-MORPHOLINOSYDNONIMINE HCL
- 3-MORPHOLINOSYDNONIMINE HYDROCHLORIDE
- 3-MORPHOLINOSYDNONIMIN HYDROCHLORIDE
- 5-AMINO-3-MORPHOLINYL-1,2,3-OXADIAZOLIUM CHLORIDE
- 5-AMINO-3-MORPHOLIN-4-YL-[1,2,3]OXADIAZOL-3-IUM, CHLORIDE
- 5-AMINO-3-(4-MORPHOLINYL)-1,2,3-OXADIAZOLIUM CHLORIDE
- LINSIDOMINE
- 3-(4-Morpholinyl)sydnone IMine Monohydrochloride
- 3-Morpholinosydnone IMine Monohydrochloride
- LinsidoMine Chlorhydrate
- MolsidoMine IMpurity A
- Molsidomine Impurity A (3-(Morpholin-4-yl)-Sydnonimine)
- LINSIDOMINE HCL
- LINSIDOMINE HYDROCHLORIDE
- SIN-I HYDROCHLORIDE
- SIN-1
- SIN-1 CHLORIDE
- SIN-1 HCL
- SIN-1 HYDROCHLORIDE
- 3-morpholinosydnoneiminehydrochloride
- 3-morpholino-sydnoneiminmonohydrochloride
- 3-(4-Morpholinyl)sydnonimine,hydrochloride
- 3-(4-MORPHOLINYL)SYDNONIMINE HYDROCHLORIDE (SIN-1)
- 3-(4-Morpholino)-sydnonimine hydrochloride
- 3-Morpholin-4-yl-1-oxa-2-aza-3-azoniacyclopenta-2,4-dien-5-amine chloride
- 3-Morpholin-4-yloxadiazol-3-ium-5-amine chloride
- SIN-1 hydrochloride,97%
- SIN-1 hydrochloride3-Morpholinosydnonimine.HCL
- Amino-3-morpholinyl-1,2,3-oxadiazoliumchloride
- SIN-1, Hydrochloride - CAS 16142-27-1 - Calbiochem
- (3-Morpholino-1,2,3-oxadiazol-3-ium-5-yl)amide hydrochloride
- Linsidomine (chloride)
- Molsidomine EP impurity A
- 3-(4-morpholinyl)-2H-oxadiazol-2-ium-5-amine chloride
- 3-(Morpholin-4-yl)sydnonimine Hydro
- Molsidomine EP Impurity A HCl (3-(Morpholin-4-yl)-Sydnonimine HCl, Linsidomine HCl)
- Molsidomine Impurity 7
- Molsidomine EP Impurity A HCl
- 16142-27-1
- C6H11N4O2Cl
- C6H12ClN4O2
- Various Metabolites and Impurities
- Metabolites & Impurities
- Nitric Oxide Reagents
