S-(-)-Carbidopa
|
|
|
- CAS-Nr.
- 28860-95-9
- Englisch Name:
- S-(-)-Carbidopa
- Synonyma:
- S(-)-CARBIDOPA;mk486;KINSON;L-3-(3,4;Carbidopa-d3;(S)-CARBIDOPA;CARBIDOPA EDMF;n-aminomethyldopa;CARBIDOPAANHYDROUS;CarbidopaUsp28/Ep5
- CBNumber:
- CB5738078
- Summenformel:
- C10H14N2O4
- Molgewicht:
- 226.23
- MOL-Datei:
- 28860-95-9.mol
|
S-(-)-Carbidopa Eigenschaften
- Schmelzpunkt:
- 203-205° (dec); mp 208°
- alpha
- D -17.3° (methanol)
- Siedepunkt:
- 367.84°C (rough estimate)
- Dichte
- 1.2616 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- -20°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- powder
- pka
- 3.40±0.14(Predicted)
- Farbe
- White to Off-White
- Stabilität:
- Unstable in Solution
- CAS Datenbank
- 28860-95-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
MW5298000 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
|
S-(-)-Carbidopa Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White Solid
Verwenden
in combinaison with levodopa as antiparkinsonian;inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC)
Definition
ChEBI: 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversi
n of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.
Allgemeine Beschreibung
Carbidopa is used for treating restless legs (RL) syndrome and periodic leg movements in sleep (PLMS). Carbidopa along with levodopa is used to treat Parkinson′s disease.
Biologische Aktivität
Peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.
S-(-)-Carbidopa Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
S-(-)-Carbidopa Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 260)Lieferanten
28860-95-9()Verwandte Suche:
- [-]-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate
- s-(-)-α-hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
- CARBIDOPAANHYDROUS
- S-(-)-CARBIDOPA,ANHYDROUS
- S-(-)-ALPHA-HYDRAZINO-3,4-DIHYDROXY-2-METHYLBENZENEPROPANOIC ACID
- S(-)-ALPHA-HYDRAZINO-3,4-DIHYDROXY-ALPHA-METHYLBENZENEPROPANOIC ACID
- S-ALPHA-HYDRAZINO-3,4-DIHYDROXY-ALPHA-METHYLBENZENEPROPANOIC ACID
- (S)-ALPHA-HYDRAZINO-ALPHA-METHYL-BETA-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
- (S)-CARBIDOPA
- Hydrazino-a-methyldopa
- L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
- L-a-Hydrazino-a-methyl-b-(3,4-dihydroxyphenyl)propionic acid
- S-(-)-a-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
- S(-)-CARBIDOPA >98% L-AROMATIC AMINO ACI D
- CarbidopaUsp28/Ep5
- (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
- (αS)-3,4-Dihydroxy-α-hydrazino-α-methylhydrocinnamic acid
- (S)-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionicacid
- (-)-L-α-Hydrazino-3,4-dihydroxy-α-MethylhydrocinaMic Acid
- 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid
- L-3-(3,4
- (S)-(-)-Carbidopa-d3 H2O
- Carbidopa-d3
- Benzenepropanoic acid, a-hydrazinyl-3,4-dihydroxy-a-Methyl-, (aS)-
- (αS)-α-hydrazinyl-3,4-dihydroxy-α-methyl-benzenepropanoic acid
- (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid
- mk486
- 4-dihydroxy-alpha-methyl-alpha-hydrazino-(s)-benzenepropanoicaci
- 4-dihydroxy-alpha-methyl-alpha-hydrazino-l-hydrocinnamicaci
- alpha-methyldopahydrazine
- -Hydrazino-3,4-dihydroxy-methylbenzenep-ropanicacid
- -Hydrazino-3,4-dihydroxy-methylhy-drocinnamicacid
- hydrazino-alpha-methyldopa
- l-alpha-methyldopahydrazine
- n-aminomethyldopa
- 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
- (+)-2-(3,4-dihydroxybenzyl)-2-hydrazinopropionic acid monohydrate
- KINSON
- CARBIDOPA EDMF
- Benzenepropanoic acid, α-hydrazinyl-3,4-dihydroxy-α-methyl-, (αS)-
- (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
- S-(-)-CARBIDOPA-D3 (RING)
- CarbidopaQ: What is
Carbidopa Q: What is the CAS Number of
Carbidopa Q: What is the storage condition of
Carbidopa Q: What are the applications of
Carbidopa
- S(-)-CARBIDOPA
- 28860-95-9
- C10H14N2O4
- CC10H14N2O4
- Aromatic L-amino acid decarboxylase inhibitor
- A to C
- BioChemical
- Biochemicals and Reagents
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- API
- Lodosyn
- L-Aromatic Amino Acid Decarboxylase
