Doxapram hydrochloride monohydrate
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- CAS-Nr.
- 7081-53-0
- Englisch Name:
- Doxapram hydrochloride monohydrate
- Synonyma:
- stimulexin;DOXAPRAM HCL;DoxapraM HCL API;Doxapram Hydrochoride;DOXAPRAM HYDROCHLORIDE;Doxapram hydrochloride CRS;DoxapraM Hydrochloride, USP;doxapramhydrochloridehydrate;Dopram hydrochloride hydrate;Doxapram hydrochloride monohyd
- CBNumber:
- CB6189200
- Summenformel:
- C24H30N2O2.ClH.H2O
- Molgewicht:
- 432.99
- MOL-Datei:
- 7081-53-0.mol
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Doxapram hydrochloride monohydrate Eigenschaften
- Schmelzpunkt:
- 217-219°
- storage temp.
- Sealed in dry,Room Temperature
- Löslichkeit
- Soluble in water, in alcohol and in methylene chloride.
- InChIKey
- ZOMBFZRWMLIDPX-UHFFFAOYSA-N
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| RIDADR |
UN 2811 6.1 / PGIII |
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| HS Code |
2934990002 |
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| Toxizität |
LD50 orally in rats: 261 mg/kg (Goldenthal) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
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Doxapram hydrochloride monohydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Doxapram is a central respiratory stimulant. It increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg. Doxapram acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation. Formulations containing doxapram have been used to increase respiration in patients with chronic pulmonary disease, respiratory depression induced by drug overdose, and to stimulate deep breathing post-anesthesia.
Chemische Eigenschaften
White or almost white, crystalline powder.
Verwenden
antibacterial
Definition
ChEBI: The monohydrate form of doxapram hydrochloride. A central and respiratory stimulant with a brief duration of action, it is used as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease,
nd of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Allgemeine Beschreibung
Doxapram, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloride hydrate (Dopram), has an obscuremolecular mechanism of action. Overall, it stimulatesrespiration by action on peripheral carotid chemoreceptors.It has use as a respiratory stimulant postanesthetically, afterCNS depressant drug overdose, in chronic obstructive pulmonarydiseases, and in the apneas. Dopram is administeredexclusively by intravenous injection. Because of the benzylalcohol content of the injectable formulation, Dopram mustnever be given to neonates.
Doxapram hydrochloride monohydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Doxapram hydrochloride monohydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 199)Lieferanten
7081-53-0()Verwandte Suche:
- 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinonehydrochloridehydr
- 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinonmonohydrochloride
- doxapramhydrochloridehydrate
- stimulexin
- 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-dephenyl-2-pyrrolidinone hydrochloride monohydrate
- DOXAPRAM HCL
- DOXAPRAM HYDROCHLORIDE
- doxapram hydrochloride monohydrate
- 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenyl-pyrrolidin-2-one hydrate hydrochloride
- 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one hydrate hydrochloride
- 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidone hydrate hydrochloride
- Doxapram Hydrochloride (200 mg)
- Doxapram Hydrochoride
- 2-Pyrrolidinone, 1-ethyl-4-2-(4-morpholinyl)ethyl-3,3-diphenyl-, monohydrochloride, monohydrate
- DOTHIEPINHYDROCHLORIDE,ANHYDROUS
- 2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-, hydrochloride, hydrate (1:1:1)
- 1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone monohydrochloride monohydrate
- Doxapram Hydrochloride Doxapram Hydrochloride
- 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-Pyrrolidinone, monohydrochloride, monohydrate(8CI)
- 1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone, hydrochloride, hydrate(1:1:1)
- DoxapraM Hydrochloride, USP
- (4S)-1-ethyl-4-[2-(Morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
- DoxapraM HCL API
- 1-Ethyl-4-(2-Morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloridehydrate
- 1-Ethyl-4-[2-(4-Morpholinyl)ethyl]-3,3-diphenyl-2-Pyrrolidinone, Monohydrochloride, Monohydrate (9CI)
- DoxapraM Hydrochoride Monohydrate
- Doxapram hydrochloride monohyd
- 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone hydrate hydrochloride
- Dopram hydrochloride hydrate
- DOPRAM HYDROCHLORIDE HYDRATE;STIMULEX HYDROCHLORIDE HYDRATE;RESPIRAM HYDROCHLORIDE HYDRATE
- Respiram hydrochloride hydrate
- Stimulex hydrochloride hydrate
- Doxapram hydrochloride CRS
- (4RS)-1-Ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3- diphenylpyrrolidin-2-one hydrochloride
- oxapramhydrochloridemonohydrate
- Doxapram hydrochloride monohydrate USP/EP/BP
- 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-one hydrochloride hydrate
- Doxapram hydrochloride (AHR-619)
- Doxapram Hydrochloride (1225000)
- 7081-53-0
- C24H30N2O2HCl
- C24H33ClN2O3
- C24H30N2O2HClH2O
- Inhibitors
- API
- MECLAN
- Other APIs
- Pharmaceutical material and intermeidates
