(R)-3-Hydroxypyrrolidine
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- CAS-Nr.
- 2799-21-5
- Englisch Name:
- (R)-3-Hydroxypyrrolidine
- Synonyma:
- (R)-PYRROLIDIN-3-OL;(3R)-Pyrrolidin-3-ol;R-HP;98%，ee99%;(R)-3-PYRROLIDINOL;(-)-3-Pyrrolidinol;(3R)-3-PYRROLIDINOL;3-PYRROLIDINOL, (R);(R)-Pyrrolidine-3-ol;R-(-)-3-PYRROLIDINOL
- CBNumber:
- CB7494161
- Summenformel:
- C4H9NO
- Molgewicht:
- 87.12
- MOL-Datei:
- 2799-21-5.mol
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(R)-3-Hydroxypyrrolidine Eigenschaften
- Schmelzpunkt:
- 15°C
- Siedepunkt:
- 215-216 °C (lit.)
- alpha
- 6.5 º (c=3.5% in MeOH)
- Dichte
- 1.078 g/mL at 20 °C (lit.)
- Brechungsindex
- n20/D 1.488(lit.)
- Flammpunkt:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 14.91±0.20(Predicted)
- Aggregatzustand
- Viscous Liquid
- Farbe
- Clear yellow to orange-brown
- Wichte
- 1.048
- Optische Aktivität
- [α]20/D +6.5°, c = 3.5 in methanol
- Wasserlöslichkeit
- Soluble in water and methanol.
- Sensitive
- Air Sensitive & Hygroscopic
- BRN
- 5376132
- CAS Datenbank
- 2799-21-5(CAS DataBase Reference)
(R)-3-Hydroxypyrrolidine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
clear yellow to orange-brown viscous liquid
Verwenden
(R)-Pyrrolidin-3-ol is used in preparation of allosteric BCR-ABL bifunctional proteolysis targeting chimera compounds.
läuterung methode
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]
(R)-3-Hydroxypyrrolidine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-3-Hydroxypyrrolidine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 309)Lieferanten
2799-21-5()Verwandte Suche:
1-Vinyl-2-pyrrolidon
1-Methyl-2-pyrrolidon
Polyvinylpyrrolidone
Pyrrolidin-3-ol
Povidone iodine
Pyrrolidin
cis-4-Hydroxy-D-prolin
1-Benzyl-(2S-trans)-hydrogen-4-hydroxypyrrolidin-1,2-dicarboxylat
7(S)-Hydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E),21(E)-trien-1,20,23-trion
METHYL-2-PYRROLIDONE
[7(S)-(1α,2β,4β,5α,7β)]-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl-(hydroxymethyl)phenylacetat-N-oxidhydrobromid
Oxaceprol
21,23-Dioxa(13)cytochalasa-13,19-dien-1,17,22-trion, 6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-,(7S,13E,16S,18R,19E)-
1-Methylpyrrolidin-3-ol
1-(Benzyl)pyrrolidin-3-ol
L-4-Hydroxyprolin
Benzolessigsäure, alpha-(hydroxymethyl)-9-methyl-3-oxa-9-azatricyclo(3.3.1.02,4)non-7-yl-ester, (7(S)-(1 alpha, 2 beta,4 beta, 5 alpha, 7 beta))-hydrobromid
Ethyl-trans-4-hydroxy-L-prolinathydrochlorid
- (3R)-3-PYRROLIDINOL
- R-(+)-3-PYRROLIDINOL 98%
- (R)-(+)-3-HYDROXYPYRROLIDINE , EE 99%
- (R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
- (3R)-Pyrrolidine-3-ol
- (R)-Pyrrolidine-3-ol
- (R)-(+)-3-Pyrrolidinol,98%
- (R)-Hydroxypyrrolidine
- (R)-(+)-3-Pyrrolidiol
- (3R)-3-Hydroxypyrrolidine
- (R)-(+)-3-Pyrrolidinol, 98% 1GR
- (R)-(+)-3-Pyrrolidinol, 98% 5GR
- (R)-3-Hydroxypyrrolidine ,98%
- (R)-pyrrolidin-3-ol (hydrobroMide)
- 3-Pyrrolidinol, (3R)-
- (R)-3-Hydroxypyrrolidine ((R)-3-Pyrrolidinol)
- 98%，ee99%
- (R) - four hydroxyl hydrogen pyrrole
- (R)-(+)-3-Hydroxypyrrolidine,99%,ee99%
- R-HP
- (R)-(+)-3-PYRROLIDINOL
- (R)-3-PYRROLIDINOL
- R-(-)-3-PYRROLIDINOL
- (R)-(+)-3-HYDROXYPYRROLIDINE
- (R)-3-HYDROXYPYRROLIDINE
- (R)-3-Pyrrolidinol,99%e.e.
- 3-PYRROLIDINOL, (R)
- (R)-3-Pyrrolidinol>
- (R)-3-Hydroxypyrrolidine USP/EP/BP
- (3R)-Pyrrolidin-3-ol
- (R)-PYRROLIDIN-3-OL
- (-)-3-Pyrrolidinol
- 2799-21-5
- Asymmetric Synthesis
- Simple Alcohols (Chiral)
- Chiral Building Blocks
- Heterocyclic Building Blocks
- Pyrrolidines
- pharmacetical
- API intermediates
- Chiral Building Blocks
- Simple Alcohols (Chiral)
- Synthetic Organic Chemistry
