Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
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- CAS-Nr.
- 68-89-3
- Bezeichnung:
- Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
- Englisch Name:
- Metamizole sodium
- Synonyma:
- METAMIZOLE;DIPYRONE;METAMIZOL SODIUM;SODIUM DIPYRONE;DIPYRONE SODIUM;novaminsulfon;novaminsulfone;sulpyrin;metamizolum;METAMIZOL SODIUM MONOHYDRATE
- CBNumber:
- CB7741339
- Summenformel:
- C13H16N3NaO4S
- Molgewicht:
- 333.34
- MOL-Datei:
- 68-89-3.mol
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Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
42/43 |
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| S-Sätze: |
36 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
PB1300000 |
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| HS Code |
29331920 |
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| Toxizität |
LD50 orl-rat: 3 g/kg ARZNAD 21,719,71 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
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Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R42/43:Sensibilisierung durch Einatmen und Hautkontakt möglich.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
solid
Verwenden
A non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Blocks PGE2-induced hyperalgesia in several models.
Definition
ChEBI: An organic sodium salt of antipyrine substituted at C-4 by a methyl(sulfonatomethyl)amino group, commonly used as a powerful analgesic and antipyretic.
Weltgesundheitsorganisation (WHO)
Metamizole sodium, a pyrazolone derivative with analgesic,
antipyretic and antinflammatory activity, was introduced in 1921 and has since been
widely available in over-the-counter products. By the early 1970s its use had been
associated, as with some other pyrazolones, with serious and sometimes fatal adverse
reactions, notably cases of blood dyscrasias including agranulocytosis, which led to
its withdrawal by some regulatory authorities. Although preparations of
metamirole sodium are prohibited in certain countries, they remain widely available in
others and, in some cases, in over-the-counter products.
Sicherheitsprofil
Poison by subcutaneous route. Moderately toxic by several other routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. Questionable carcinogen with experimental neoplastigenic data. See also SULFONATES. When heated to decomposition it emits very toxic fumes of NOx,, Na2O, and SOx,.
Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 302)Lieferanten
68-89-3(Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat)Verwandte Suche:
- nevralgina
- noramidopyrinemethanesulfonatesodium
- noramidopyrinium-methanesulphatenatrium
- noraminopyrinemethanesulfonatesodium
- optalgin
- paralgin
- phenyldimethylpyrazolonmethylaminomethanesodiumsulfonate
- pyralgin
- pyretin
- pyrojec
- sodium1-phenyl-2,3-dimethyl-4-methylaminopyrazolon-n-methanesulfonate
- sodium1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate
- sodium4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolone4-methanesulfonate
- sodiummethylaminoantipyrinemethanesulfonate
- sodiumnoramidopyrinemethanesulfonate
- sodiumphenyldimethylpyrazolon-methylamino-methanesulfonate
- sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1h-pyrazol-4-yl)methylamino]methanesulfonate
- Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
- Alangin
- Analgin(metamizole)
- Analgin/MetamizoleSodium
- Dipyrone(MetamizoleSodium
- BENZALAGEN
- LABOTEST-BB LT00771955
- metamizole sodium
- Methanesulfonic acid, (2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino-, sodium salt
- [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylamino] methanesulphonate
- Dipyrone Hcl / Analgin
- NoramidopyrineMethanesulfonatSodium
- N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-N-methylamino methanesulfoxylote sodium salt
- Analgin sodium
- N-Methyl-N-(2,3-dihydro-1,5-dimethyl-2-phenyl-3-oxo-1H-pyrazol-4-yl)aminomethanesulfonic acid sodium
- NSC-73205
- 1-[(2,3-Dihydro-1,5-diMethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)MethylaMino]Methanesulfonic Acid SodiuM Salt
- Algopyrin
- Anador
- Andolor
- ARPF
- Gifaril
- Lisador
- MethaMizole SodiuM
- Metilon
- Sulpin
- analgin API
- METAMIZOLE SODIUM MONOHYDRATE PH EUR
- 1-phenyl-2,3-dimethyl-4-methylamino-5-pyrazolon-n-methanesulfonsaeurennatriu
- 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium
- 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium
- 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate
- 4-sodiummethanesulfonatemethylamine-antipyrine
- alginodia
- algocalmin
- methylaminoantipyrinesodiummethanesulfonate
- methylaminophenyldimethylpyrazolonemethanesulfonatesodium
- methylmelubrin
- methylmelubrine
- narone
- neomelurbrin
