Diclazepam
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- CAS-Nr.
- 2894-68-0
- Englisch Name:
- Diclazepam
- Synonyma:
- 2-chlorodiazepam;Ro 5-3448;DiclazepaM;etizolam powder;o-Chlorodiazepam;diclazepam powder;Diclazepam, Ro5-3448;Diclazepam USP/EP/BP;2-chlorodiazepam /Diclazepam;Diclazepam, 2'-Chlorodiazepam
- CBNumber:
- CB81331206
- Summenformel:
- C16H12Cl2N2O
- Molgewicht:
- 319.19
- MOL-Datei:
- 2894-68-0.mol
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Diclazepam Eigenschaften
- Schmelzpunkt:
- 217-219℃ (dichloromethane ethyl ether )
- Siedepunkt:
- 524.6±50.0 °C(Predicted)
- Dichte
- 1.35±0.1 g/cm3 (20 ºC 760 Torr)
- Löslichkeit
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
- Aggregatzustand
- A neat solid
- pka
- 1.75±0.25(Predicted)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Diclazepam Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Diclazepam, also known as 2-chlorodiazepam and chlorodiazepam, is classed in the benzodiazepam family, and is therefore a diazepam analogue.It was first synthesized by Leo Sternbach and his team at Hoffman-La Roche in 1960, but it was not pursued as a pharmaceutical product.Diclazepam dosage, efficacy or safety in humans has never been formally studied. In animals, however, it is known to have very similar effects to flubromazepam and diazepam itself. Its effects include working as an anticonvulsant and anxiolytic, a sedative, a hypnotic, an amnesiac and as a skeletal muscle relaxant. It may have adverse effects such as drowsiness, and cognitive impairments such as short term memory impairment.
Diclazepam has been assessed as having an elimination half-life of around 42 hours in most animals. In the body, it undergoes N-demethylation, resulting in the creation of delorazepam. The delorazepam can be detected in the subject’s urine for approximately six days. It also metabolises into lormetazepam (detectable for 19 days) and lorazepam (detectable for 11 days). This suggests that cytochrome P450 enzymes are also engaging in hydroxylation of the compound at the same time as the N-demethylation.
Diclazepam Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2894-68-0()Verwandte Suche:
- 1-Methyl-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one
- 1-Methyl-7-chloro-5-(2-chlorophenyl)-1H-1,4-benzodiazepine-2(3H)-one
- 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one
- o-Chlorodiazepam
- Ro 5-3448
- DiclazepaM
- 2H-1,4-Benzodiazepin-2-one,7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-Methyl-
- 7-chloro-5-(2-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one
- 7-Chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Diclazepam, Ro5-3448
- Benzodiazepines Intermediate 2
- Diclazepam cas 2894-68-0 C16H12Cl2N2O white powder purity 99.9%
- diclazpam ALP powder wickr me:lolychem668
- diclazepam powder
- etizolam powder
- Etizolam powder/xanax pwder/hot sale hongkong supplier(wickr me:lolychem668)
- 2-chlorodiazepam /Diclazepam
- Diclazepam USP/EP/BP
- 2-chlorodiazepam
- Diclazepam, 2'-Chlorodiazepam
- 7- chloro -5-(2- chlorophenyl) -1,3- dihydro -1- methyl -2H-1,4- benzodiazepine -2- one
- 2894-68-0
- research chemical
- medical intermediate
