Fluorometholon

Fluorometholone Struktur
426-13-1
CAS-Nr.
426-13-1
Bezeichnung:
Fluorometholon
Englisch Name:
Fluorometholone
Synonyma:
FML;Flulon;U 8614;Ursnon;Fluoron;Fluaton;FML SOP;oxylone;trilcin;Fluor-Op
CBNumber:
CB9461978
Summenformel:
C22H29FO4
Molgewicht:
376.46
MOL-Datei:
426-13-1.mol

Fluorometholon Eigenschaften

Schmelzpunkt:
292-303°
alpha 
+52~+60°(c=1, pyridine) (D/20℃)
Siedepunkt:
527.1±50.0 °C(Predicted)
Dichte
1.0573 (rough estimate)
Brechungsindex
55 ° (C=1, Pyridine)
storage temp. 
2-8°C
Löslichkeit
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka
12.50±0.70(Predicted)
Farbe
White to Off-White
Wasserlöslichkeit
30mg/L(25 ºC)
Merck 
14,4175
CAS Datenbank
426-13-1(CAS DataBase Reference)
EPA chemische Informationen
Fluorometholone (426-13-1)

Sicherheit

Kennzeichnung gefährlicher Xn
R-Sätze: 20/21/22
S-Sätze: 36
WGK Germany  3
RTECS-Nr. TU3834100
HS Code  29189900
Toxizität rat,LD,oral,> 2gm/kg (2000mg/kg),Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2349, 1974.

Fluorometholon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

White powder

Verwenden

Fluorometholone is a glucocorticoid; anti-inflammatory.

Definition

ChEBI: A member of the class of glucocorticoids that is Delta1-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Allgemeine Beschreibung

Fluorometholone, 9-fluoro-11β,17-dihydroxy-6α-methylpregn-4-ene-3,20-dione(Fluor-Op, FML), lacks the typical C21 OH group of GCsand is used exclusively in ophthalmic products. The 17-acetateof fluorometholone is also used as an ophthalmic suspension(Flarex).

Fluorometholon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Fluorometholon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 335)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 15956 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21688 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
bruce@xrdchem.cn CHINA 566 55
Shanxi Naipu Import and Export Co.,Ltd
+86-13734021967 +8613734021967
kaia@neputrading.com China 1011 58
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953
info@konochemical.com China 2995 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58

426-13-1(Fluorometholon)Verwandte Suche:


  • (6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • 21-Desoxy-9a-fluoro-6-methylprednisolone
  • 6a-Methyl-9a-fluoro-21-desoxyprednisolone
  • 9a-Fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
  • Flulon
  • Fluoron
  • (6S,8S,9R,10S,11S,13S,14S,17R)-17-ethanoyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • Fluorometholone,11β,17α-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
  • Fluorometholone (200 mg)
  • luoroMethalone
  • (6α,11β)-9-Fluoro-11,17-dihydroxy-6-Methylpregna-1,4-diene-3,20-dione
  • Fluaton PVA
  • 11β,17α-dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
  • FLUOROMETHOLONE,POWDER,USP
  • 21-Desoxy-9α-fluoro-6-methylprednisolone
  • 6α-Methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione
  • 6α-Methyl-9α-fluoro-21-desoxyprednisolone
  • Efflumidex
  • Fluaton
  • Flumetholon
  • Fluormetholon
  • Fluor-Op
  • FML
  • FML Forte
  • FML Liquifilm
  • FML SOP
  • Loticort
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6α,11β)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-6α-methyl- (6CI, 7CI, 8CI)
  • U 8614
  • Ursnon
  • Fluorometholone solution,100ppm
  • FLUOROMETHOLONE
  • fluoromethalone
  • 1,4-PREGNADIEN-9-ALPHA-FLUORO-6-ALPHA-METHYL-11-BETA, 17-DIOL-3,20-DIONE
  • 11BETA,17ALPHA-DIHYDROXY-9-FLUORO-6-METHYL-1,4-PREGNADIENE-3,20-DIONE
  • 11-BETA,17-ALPHA-DIHYDROXY-9-FLUORO-6-METHYL-4-ANDROSTEN-3-ONE
  • 11b,17a-dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
  • 21-DESOXY-9A-FLUORO-6-ALPHA-METHYLPREDNISOLONE
  • 9a-fluoro-11b,17a-dihydroxy-6a-methyl-1,4-pregnadiene-3,20-dione
  • 9-FLUORO-11,17-DIHYDROXY-6-METHYLPREGNA-1,4-DIENE-3,20-DIONE
  • 20-dione,9-fluoro-11-beta,17-dihydroxy-6-alpha-methyl-pregna-4-diene-3
  • 9-fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
  • cortilet
  • delmeson
  • nsc33001
  • oxylone
  • pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-6-methyl-,(6alpha,11be
  • pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-6-methyl-,(6-alpha,11-be
  • trilcin
  • 9-alpha-fluoro-11-beta,17-alpha-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
  • Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-6-Methyl-, (6a,11b)-
  • 4-amino-1-methyl-3-pyrazolo[3,4-d]pyrimidinecarbonitrile
  • Fluorometholone 426-13-1
  • uorometholone
  • Fluorometholone Fluorometholone
  • Fluorometholone>
  • Fluorometholone RS
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