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Fluoxetine Hcl

Fluoxetine Hcl Structure
Fluoxetine Hcl structure
CAS No.
59333-67-4
Chemical Name:
Fluoxetine Hcl
Synonyms
Zepax;TSCOT;PROZAC;Prizma;Prodep;Sanzur;Sinzac;Zactin;LY-110;SARAFEM
CBNumber:
CB00126492
Molecular Formula:
C17H19ClF3NO
Molecular Weight:
345.79
MDL Number:
MFCD00214288
MOL File:
59333-67-4.mol
Last updated:2024-05-18 08:51:57
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Fluoxetine Hcl Properties

Melting point 158-159°C
Flash point 9℃
storage temp. -20°C Freezer
solubility H2O: 4 mg/mL
form solid
color white
BCS Class 1
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 59333-67-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII I9W7N6B1KJ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09,GHS05
Signal word  Danger
Hazard statements  H318-H400-H302-H315
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P273-P391-P501-P264-P270-P301+P312-P330-P501
Hazard Codes  Xn,T,F
Risk Statements  22-38-41-39/23/24/25-23/24/25-11
Safety Statements  26-36/37/39-45-36/37-16-7
WGK Germany  3
RTECS  UI4050000
HazardClass  IRRITANT
HS Code  29221990
Toxicity LD50 in mice, rats (mg/kg): 248, 452 orally (Stark)

Fluoxetine Hcl price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 134805 TSCOT 59333-67-4 100ug $539 2021-12-16 Buy
Medical Isotopes, Inc. 10377 Fluoxetine hydrochloride 59333-67-4 50mg $190 2021-12-16 Buy
Biorbyt Ltd orb602629 SLC46A2 59333-67-4 10μg $290.7 2021-12-16 Buy
Abosyn 61-11482 Fluoxetine hydrochloride 95-98% 59333-67-4 5g $135 2021-12-16 Buy
Product number Packaging Price Buy
134805 100ug $539 Buy
10377 50mg $190 Buy
orb602629 10μg $290.7 Buy
61-11482 5g $135 Buy

Fluoxetine Hcl Chemical Properties,Uses,Production

Description

Fluoxetine Hcl is the hydrochloride salt form of fluoxetine, a diphenhydramine derivative and selective serotonin reuptake inhibitor with antidepressant, anti-anxiety, antiobsessional and antibulimic activity and with potential immunomodulating activity. 

Cupric Acetate.jpg

Biological Activity

Fluoxetine Hcl is a selective serotonin reuptake inhibitor. Binds to the human 5-HT transporter with a Ki of 0.9 nmol/l and is between 150- and 900-fold selective over 5-HT1A, 5-HT2A, H1, α1, α2-adrenergic, and muscarinic receptors. Fluoxetine also inhibits assembly and activation of the NLRP3-ASC inflammasome and prevents degeneration of retinal pigmented epithelium (RPE) cells in an animal model of dry age-related macular degeneration (AMD).

Mechanism of action

Upon administration, fluoxetine binds to the presynaptic serotonin (5-HT) receptor resulting in negative allosteric modulation of the receptor complex, thereby blocking recycling of serotonin by the presynaptic receptor. Inhibition of serotonin reuptake by fluoxetine enhances serotonergic function through serotonin accumulation in the synaptic space, resulting in long-term desensitization and downregulation of 5-HT receptors, preventing 5-HT-mediated signaling and leading to antidepressant, anti-anxiety, antiobsessional and antibulimic effects.

Side effects

Common effects include: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Fluoxetine Hcl Preparation Products And Raw materials

Raw materials

Acetophenone

Preparation Products

Fluoxetine Hcl Suppliers

Global( 196)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618740459177 sarah@tnjone.com China 1142 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 3001 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21689 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503282 alice@crovellbio.com China 8829 58
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8615821988213 info@longyupharma.com China 2531 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
Supplier Advantage
Shaanxi TNJONE Pharmaceutical Co., Ltd 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Hebei Guanlang Biotechnology Co., Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Shanghai Longyu Biotechnology Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from Fluoxetine Hcl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fluoxetine Hydrochloride; Fluoxetine HCl pictures 2024-05-18 Fluoxetine Hydrochloride; Fluoxetine HCl
59333-67-4
 US $0.00 / kg 1kg 99% 10000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Fluoxetine pictures 2021-09-07 Fluoxetine
54910-89-3
 US $10.00 / Kg/Bag 1Kg/Bag Above 99% 5000kg/month Hebei Zhanyao Biotechnology Co. Ltd
  • Fluoxetine pictures
  • Fluoxetine
    54910-89-3
  • US $10.00 / Kg/Bag
  • Above 99%
  • Hebei Zhanyao Biotechnology Co. Ltd

59333-67-4(Fluoxetine Hcl)Related Search:

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4-Trifluoromethylphenol N-Methyl Fluoxetine Hydrochloride 3-Chlorobenzotrifluoride N-Methyl-3-phenylpropan-1-aMine hydrochloride (RelCpd B) 3-(DIMETHYLAMINO)-1-PHENYLPROPAN-1-ONE
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NORFLUOXETINE HYDROCHLORIDE (4-hydroxy-1-methyl-4-phenyl-3-piperidyl)-phenyl-methanone ALPHA-METHYLBENZYL ALCOHOL Fluoxetine Hcl

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SARAFEM Affectine Alzac 20 N-Methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propylamine hydrochloride Fluoxetine Hydrochloride (200 mg) Methanol (Test Fluoxetine HCl, 1.0 mg/mL (as free base)) N-METHYL-3-[(4-TRIFLUOROMETHYL)PHENOXY]-3-PHENYLPROPYLAMINE HYDROCHLORIDE (+/-)-N-METHYL-3-PHENYL-3-[(ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLYL)OXY]PROPYLAMINE, HCL (+/-)-N-METHYL-GAMMA-[4-(TRIFLUOROMETHYL)PHENOXY]-BENZENEPROPANAMINE HYDROCHLORIDE PROZAC PROZAC(R) Fluoxetin HCL Fluoxetine hydrochloride, Vetranal FluvastatinF4:Tert-Butyl(E)-3,5-Dihydroxy-7-[3'-(4"-Fluorophenyl)-1'-Methylethyl-Indol-2'-Yl]Hept-6-Enoate Floxitine Hcl 54910-89-3, LY-110, Prozac (±)-n-methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride FLUOXETINEHYDROCHLORIDE,USP LUOXETINE HCL Deproxin DigassiM Zepax Pragmaten Prizma Prodep Propylamine, N-methyl-3-phenyl-3-(p-trifluoromethylphenoxy)-, hydrochloride Prozac 20 Rowexetina Sanzur Sinzac Zactin SLC46A2 TSCOT N-methyl-3 FLUOXETINE HCL DL-N-METHYL-3-(P-TRIFLUOROMETHYLPHENOXY)-3-PHENYLPROPYLAMINE, HCL LY-110 LY-110140 LY110140 HYDROCHLORIDE Fluoxetine hydrochloride solution Fluoxetine hydrochloride CRS FLUOXETINE HYDROCHLORIDE USP/EP/BP Fluoxetine intermediate，FLUOXETINE HYDROCHLORIDE 59333-67-4 C17H18F3NOHCI C17H19ClF3NO C17H18H3NOHCl C17H13F3N0D5HCl C18H19F3NO C17H18F3NOHCl C17F3H18NOHCl Biochemicals and Reagents Application Index BioChemical Inhibitors Enzymes, Inhibitors, and Substrates Xenobiotics and Drug Metabolism Cell Signaling Enzymes