Vecuronium
- CAS No.
- 50700-72-6
- Chemical Name:
- Vecuronium
- Synonyms
- vecuronium;norcuron;Vecuronim Bromide;VBMC;nc-45;orgnc45;Musculax;Muscurate;mide,diacetate;VECRONIUM BROMIDE
- CBNumber:
- CB00127711
- Molecular Formula:
- C34H57BrN2O4
- Molecular Weight:
- 637.73138
- MDL Number:
- MFCD00867762
- MOL File:
- 50700-72-6.mol
Melting point | 227-229°C |
---|---|
alpha | +30.5~+35.0゜(D/20℃)(c=0.5,dil.HCl) |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in acetonitrile and in anhydrous ethanol. |
color | White |
Merck | 14,9941 |
BRN | 4837308 |
Stability | Hygroscopic |
InChIKey | VEPSYABRBFXYIB-PWXDFCLTSA-M |
CAS DataBase Reference | 50700-72-6(CAS DataBase Reference) |
FDA UNII | 7E4PHP5N1D |
NCI Drug Dictionary | Norcuron |
ATC code | M03AC03 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37/38-22 | |||||||||
Safety Statements | 26-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TN4875000 | |||||||||
HS Code | 2933399090 | |||||||||
Toxicity | LD50 in mice: 0.061 mg/kg i.v. (Buckett) | |||||||||
NFPA 704 |
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Vecuronium price More Price(39)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 76904 | Vecuronium bromide ≥97.0% (TLC) | 50700-72-6 | 10mg | $140 | 2024-03-01 | Buy |
Sigma-Aldrich | 1711155 | Vecuronium bromide United States Pharmacopeia (USP) Reference Standard | 50700-72-6 | 50mg | $436 | 2024-03-01 | Buy |
TCI Chemical | V0120 | Vecuronium Bromide Hydrate >98.0%(HPLC)(T) | 50700-72-6 | 100mg | $238 | 2024-03-01 | Buy |
Cayman Chemical | 15603 | Vecuronium (bromide) ≥98% | 50700-72-6 | 10mg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 15603 | Vecuronium (bromide) ≥98% | 50700-72-6 | 50mg | $118 | 2024-03-01 | Buy |
Vecuronium Chemical Properties,Uses,Production
Description
Vecuronium is a bis quaternary nitrogen compound that acts by competitively binding to nicotinic cholinergic receptors. It is a nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures. The binding of vecuronium decreases the opportunity for acetylcholine to bind to the nicotinic receptor at the postjunctional membrane of the myoneural junction. As a result, depolarization is prevented, calcium ions are not released, and muscle contraction does not occur.
Side effects
Common side effects of Vecuronium include: muscle weakness; redness or irritation at the injection site.
Serious side effects of Vecuronium include: hives; difficulty breathing; swelling in the face, lips, tongue, or throat; weak or shallow breathing; ongoing muscle weakness; loss of movement in any part of the body; dizziness, and fever.
Safety
Vecuronium is a short-acting non-depolarizing muscle relaxant structurally related to pancuronium, with a time to onset of action of 1.5 to 2.0 minutes after intravenous bolus infusion, with a duration of effect that lasts only 30 to 40 minutes. It has few cardiovascular side effects and is cleared rapidly by biliary excretion. Thus, it is safer than pancuronium in the presence of renal failure. Interference with excretion or potentiation of effect has been suggested when vecuronium is used in combination with metronidazole, aminoglycosides, and hydantoins. However, no problems have been observed in infants receiving these agents and vecuronium in its usual dosage. Acidosis can be expected to enhance the neuromuscular blockade provided by vecuronium and alkalosis to antagonize it.
Vecuronium Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jinan Good Medical Technology Co.,Ltd | +86-53155562571 +86-008613553167512 | 13553167512@139.com | China | 25 | 58 |
Beijing Mesochem Technology Co.,Ltd | +8613651027935 | rachel@mesochem.com | China | 191 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12470 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
Beijing Yibai Biotechnology Co., Ltd | 0086-182-6772-3597 | sales04@yibaibiotech.com | CHINA | 419 | 58 |
View Lastest Price from Vecuronium manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-13 | Vecuronium bromide
50700-72-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2021-01-29 | Vecuronium bromide
50700-72-6
|
US $100.00 / KG | 1KG | 99%min | 200TON | Hebei Guanlang Biotechnology Co., Ltd. | ||
2019-07-06 | Vecuronium bromide
50700-72-6
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
- Vecuronium bromide
50700-72-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- Vecuronium bromide
50700-72-6
- US $100.00 / KG
- 99%min
- Hebei Guanlang Biotechnology Co., Ltd.
- Vecuronium bromide
50700-72-6
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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