ChemicalBook >> CAS DataBase List >>Riboflavine
Riboflavine
- CAS No.
- 83-88-5
- Chemical Name:
- Riboflavine
- Synonyms
- VITAMIN B2;RIBOFLAVINE;(-)-RIBOFLAVIN;Flavaxin;Riboflavin Vitamin B2;Riboflavin Universal;Vitamin B2 (Riboflavine);VIT B2;LACTOFLAVIN;Riboflavin CRS
- CBNumber:
- CB00128413
- Molecular Formula:
- C17H20N4O6
- Molecular Weight:
- 376.36
- MDL Number:
- MFCD00005022
- MOL File:
- 83-88-5.mol
- MSDS File:
- SDS
Last updated:2024-05-21 21:51:03
| Melting point | 290 °C (dec.)(lit.) |
|---|---|
| alpha | -135 º (c=5, 0.05 M NaOH) |
| Boiling point | 504.93°C (rough estimate) |
| Density | 1.2112 (rough estimate) |
| refractive index | -135 ° (C=0.5, JP Method) |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | Very slightly soluble in water, practically insoluble in ethanol (96 per cent). Solutions deteriorate on exposure to light, especially in the presence of alkali. It shows polymorphism (5.9). |
| form | Powder |
| pka | 1.7(at 25℃) |
| color | Yellow to orange |
| PH | 5.5-7.2 (0.07g/l, H2O, 20°C) |
| Odor | Slight odour |
| PH Range | 6 |
| Water Solubility | 0.07 g/L (20 ºC) |
| Sensitive | Light Sensitive |
| Merck | 14,8200 |
| BRN | 97825 |
| BCS Class | 1 |
| Stability | Stable, but light-sensitive. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. May be moisture sensitive. |
| InChIKey | AUNGANRZJHBGPY-SCRDCRAPSA-N |
| LogP | -2.009 (est) |
| FDA 21 CFR | 184.1695; 582.5695; 73.450; 101.9; 104.20; 107.10; 107.100; 136.115; 137.165; 137.185; 310.545 |
| Substances Added to Food (formerly EAFUS) | RIBOFLAVIN |
| SCOGS (Select Committee on GRAS Substances) | Riboflavin |
| CAS DataBase Reference | 83-88-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | riboflavin; vitamin B2 |
| FDA UNII | TLM2976OFR |
| NCI Drug Dictionary | riboflavin |
| ATC code | S01XA26 |
| NIST Chemistry Reference | Riboflavine(83-88-5) |
| EPA Substance Registry System | Riboflavin (83-88-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 | |||||||||
| Hazard Codes | F,T | |||||||||
| Risk Statements | 11-23/24/25-39/23/24/25 | |||||||||
| Safety Statements | 24/25-45-36/37-16 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | VJ1400000 | |||||||||
| F | 8-10-21 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29362300 | |||||||||
| Toxicity | LD50 in rats (g/kg): >10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin) | |||||||||
| NFPA 704 |
|
Riboflavine price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V-067 | (−)-Riboflavin 100?μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1?mL, Cerilliant? | 83-88-5 | 1mL | $129 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR1054 | Riboflavin Pharmaceutical Secondary Standard; Certified Reference Material | 83-88-5 | 1g | $99.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 555682 | Riboflavin-CAS83-88-5-Calbiochem Awatersolublevitamininvolvedinthesynthesisofflavinmononucleotide(FMN) | 83-88-5 | 10g | $48 | 2024-03-01 | Buy |
| Sigma-Aldrich | 5.00257 | Riboflavin E 101 (i) | 83-88-5 | 2.5kg | $1364 | 2024-03-01 | Buy |
| Sigma-Aldrich | 47861 | Riboflavin (B2) analytical standard | 83-88-5 | 1000mg | $23.2 | 2024-03-01 | Buy |
Riboflavine Chemical Properties,Uses,Production
Chemical Properties
Riboflavin is moderately soluble in water (10–13 mg/dl) and ethanol but insoluble in ether, chloroform, and acetone. It is soluble but unstable under alkaline conditions.
The catalytic functions of riboflavin are carried out primarily at positions N-1, N-5, and C-4 of the isoalloxazine nucleus. In addition, the methyl group at C-8 participates in covalent bonding with enzyme proteins.
Uses
People most commonly use riboflavin to prevent riboflavin deficiency, for migraine, and for high levels of homocysteine in the blood. It's also used for acne, muscle cramps, and many other conditions, but there is no good scientific evidence to support these other uses.
Side effects
In some people, riboflavin can cause the urine to turn a bright yellow color. It may also cause nausea.
Toxicology
Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Source
Riboflavin is widely found in both plant- and animal-based foods, including milk, meat, eggs, nuts, enriched flour, and green vegetables.
Dosage
When taken by mouth: Riboflavin is likely safe for most people in doses of up to 400 mg daily. In some people, riboflavin can cause the urine to turn a bright yellow color. It may also cause nausea. Pregnancy and breast-feeding: Riboflavin is likely safe when consumed in amounts commonly found in foods. The recommended intake is 1.4 mg daily during pregnancy and 1.6 mg daily during lactation. Children: Riboflavin is likely safe for most children when consumed in amounts commonly found in foods. Higher doses of 100-200 mg daily have also been safely used.
Riboflavine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 860)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 122 | 58 |
| XI AN SGONEK BIOLOGICAL TECHNOLOGY CO., LTD | 15202951039 | jason@sgonekbio.com | China | 268 | 58 |
| Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 | admin@china-yime.com | China | 563 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | sales06@tgybio.com | China | 941 | 58 |
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View Lastest Price from Riboflavine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-25 | Vitamin B2 Riboflavine
83-88-5
|
US $0.00 / kg | 1kg | 99% | 1000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-03-12 | Riboflavine
83-88-5
|
US $0.00 / g | 1g | 98% HPLC | 1000kg | shandong perfect biotechnology co.ltd | |
 |
2024-03-08 | Riboflavine
83-88-5
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
-
- Vitamin B2 Riboflavine
83-88-5
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Riboflavine
83-88-5
- US $0.00 / g
- 98% HPLC
- shandong perfect biotechnology co.ltd
-
- Riboflavine
83-88-5
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
83-88-5(Riboflavine)Related Search:
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SABOURAUD CHLORAMPHENICOL CONTACT
RIBOFLAVIN
RIBIPCA
VITAMIN G
BEFLAVINE
(-)-LACTOFLAVIN
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
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7,8-Dimethyl-10-(1' d-ribityl)isoalloxazine
Hyre
Isoalloxazine, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-
Isoalloxazine, 7,8-dimethyl-10-D-ribityl-
Lactobene
Lactoflavine, zinvit-g
Ovoflavin
Ovoflavine
Q 14
Ribocrisina
Riboderm