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Vitamine D3

CAS No.
67-97-0
Chemical Name:
Vitamine D3
Synonyms
CHOLECALCIFEROL;VITAMIN D;COLECALCIFEROL;Vitamin D3 Crystal;VITAMINE D3;CALCIOL;Manufacturer;Cholecalciferol CRS;Cholecalciferol (Vitamin D3);Deparal
CBNumber:
CB00129318
Molecular Formula:
C27H44O
Lewis structure
c27h44o lewis structure
Molecular Weight:
384.64
MDL Number:
MFCD00078131
MOL File:
67-97-0.mol
MSDS File:
SDS
Last updated:2024-05-22 11:23:49

Vitamine D3 Properties

Melting point 83-86 °C(lit.)
alpha 105 º (c=0.8, EtOH 25 ºC)
Boiling point 451.27°C (rough estimate)
Density 0.9717 (rough estimate)
vapor pressure 2.0 x l0-6 Pa (20 °C, est.)
refractive index 1.5100 (estimate)
Flash point 14 °C
storage temp. -20°C
solubility Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in trimethylpentane and in fatty oils. It is sensitive to air, heat and light. Solutions in solvents without an antioxidant are unstable and are to be used immediately. A reversible isomerisation to pre-cholecalciferol takes place in solution, depending on temperature and time. The activity is due to both compounds.
pka 14.74±0.20(Predicted)
form powder
color White
Odor odorless
Water Solubility <0.1 g/L (20 ºC)
Sensitive Air & Light Sensitive
Merck 14,10019
BRN 2339331
Stability Light Sensitive, Temperature Sensitive
InChIKey QYSXJUFSXHHAJI-YRZJJWOYSA-N
LogP 9.085 (est)
Substances Added to Food (formerly EAFUS) VITAMIN D-3
SCOGS (Select Committee on GRAS Substances) Vitamin D3 (cholecalciferol)
FDA 21 CFR 310.545
CAS DataBase Reference 67-97-0(CAS DataBase Reference)
EWG's Food Scores 2-5
FDA UNII 1C6V77QF41
NCI Dictionary of Cancer Terms cholecalciferol
NCI Drug Dictionary cholecalciferol
NIST Chemistry Reference Cholecalciferol(67-97-0)
EPA Substance Registry System Cholecalciferol (67-97-0)

Pharmacokinetic data

Protein binding 50-80%
Excreted unchanged in urine Minimal
Biological half-life 50 days

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H300+H310+H330-H372
Precautionary statements  P260-P262-P280-P302+P352+P310-P304+P340+P310-P314
Hazard Codes  Xn,T
Risk Statements  26-24/25 -48/25
Safety Statements  28-45-36/37
WGK Germany  2
RTECS  VS2900000
8-10-23
TSCA  Yes
HS Code  29362990
Toxicity LD50 oral in rat: 42mg/kg
NFPA 704
1
1

Vitamine D3 price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V-025 Vitamin D3 solution 1?mg/mL in ethanol, ampule of 1?mL, certified reference material, Cerilliant? 67-97-0 1mL $99 2024-03-01 Buy
Sigma-Aldrich 740292 Vitamin D3 solution 100μg/mL in ethanol, 97% (CP) 67-97-0 1ml $200 2024-03-01 Buy
Sigma-Aldrich 47763 Cholecalciferol (D3) analytical standard 67-97-0 100mg $34 2024-03-01 Buy
Sigma-Aldrich 1131009 Cholecalciferol United States Pharmacopeia (USP) Reference Standard 67-97-0 5x30mg $457 2024-03-01 Buy
Sigma-Aldrich BP787 Colecalciferol British Pharmacopoeia (BP) Reference Standard 67-97-0 500MG $252 2023-06-20 Buy
Product number Packaging Price Buy
V-025 1mL $99 Buy
740292 1ml $200 Buy
47763 100mg $34 Buy
1131009 5x30mg $457 Buy
BP787 500MG $252 Buy

Vitamine D3 Chemical Properties,Uses,Production

Description

Vitamine D3 is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Having the right amount of vitamin D3, calcium, and phosphorus is important for building and keeping strong bones.

Vitamine D3.png

Uses

Vitamin D3 is used to treat and prevent bone disorders (such as rickets, osteomalacia). Vitamin D3 with calcium is used to treat or prevent bone loss (osteoporosis). Vitamin D3 is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia).

benefits

Vitamin D3 (cholecalciferol) has a few health benefits, including helping the body absorb calcium.Vitamin D3, through its active metabolite, 1,25- (OH)2D3, also plays an important role in maintaining calcium homeostasis by enhancing intestinal calcium absorption, PTH-induced mobilization of calcium from bone, and calcium reabsorption in the kidney.

Usage

Vitamin D3 is a fat-soluble vitamin. This means that taking it with fat helps it absorb better. It doesn’t matter what time of day you take it, but you should eat fat-containing food when you do.

Side effects

Stomach upset

Nausea

Vomiting

Constipation

Bone pain

Muscle weakness

An increased risk of bone fractures

Toxicity

Vitamin D3 is generally regarded as safe, but it can on rare occasions cause toxic effects if you take too much. This is referred to as hypervitaminosis D.With vitamin D toxicity, the balance of minerals like calcium and potassium is upset. This can lead to a condition known as hypercalcemia, in which too much calcium builds up in the body.

Source

Foods such as fish, beef liver, eggs, and cheese naturally contain vitamin D3. It can also be produced in the skin following exposure to ultraviolet (UV) radiation from the sun.

Global( 865)Suppliers
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Leading Chemical and Trading Co.,Ltd
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Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 3001 58

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Vegan Vitamin D3;Vegan D3; D3 Vegan pictures 2024-03-29 Vegan Vitamin D3;Vegan D3; D3 Vegan
67-97-0
US $0.00 / kg 1kg 100000iu/g 10000 kg Leading Chemical and Trading Co.,Ltd
Vitamine E phosphate disodium salt pictures 2023-01-31 Vitamine E phosphate disodium salt
US $100.00 / KG 1KG 99% 5000kg/week Hebei Mojin Biotechnology Co., Ltd
Vitamin D3 pictures 2021-11-02 Vitamin D3
67-97-0
US $80.00 / G 10G pharm.grade 100kgs Baoji Guokang Healthchem co.,ltd
  • Vitamin D3 pictures
  • Vitamin D3
    67-97-0
  • US $80.00 / G
  • pharm.grade
  • Baoji Guokang Healthchem co.,ltd
Vitamin D3 solution Vitamin D3-d3 Cholecalciferol (6,19,19-d3) Cholecalciferol d6 10-Secocholesta-5,7,10(19)-trien- (5Z,7E,3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol 3Z-[2E-[(1R,3aS,7aR)-1S-[1R,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol (+)-VITAMIN D/3, CRYSTALLINE, 99+% CHOLECALCIFEROL, PH EUR CHOLECALCIFEROL CRYSTALLINE CHOLECALCIFEROL, USP VITAMIN D3 99+% VitaminD3(Cholecalciferol40000Iu) VitaminD3MedicalGrade VitaminD2MedicalGrade VitaminD3CrystalPowder(40,000,000Iu) Cholecalciferol/VitamineD3 VitaminD3U.S.P. VitaminD/VitaminD3 cholecalciferol,d3 d3-vicotrat D3-Vigantol Delsterol duphafrald31000 Ebivit Micro-dee neodohyfrald3 Provitina rampage Ricketon Trivitan VidDe-3-hydrosol 5,7,10(19)-CHOLESTATRIEN-3BETA-OL-9,10-SECO Cholecalciferol, USP Grade 9,10-Secocholesta-5,7,19(19)-trien-3-OL-(3B,5Z,7E)-choleciferol, USP Grade vitamin D3 ~40000 U/mg CHOLECALCIFEROL, PHARMA Vitamin D3 colecalciferol, (+)-5,7-cholestadien-3в-ol CHOLECALCIFEROL,CRYSTAL,USP 3-[2-[7a-methyl-1-(6-methylheptan-2-yl)-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol DEHYDROCHOLESTEROL, 7-(RG) 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)- (9CI) 1,3-Cyclohexanediol, 4-methylene-5-[2-[octahydro-1-[1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, [1S-[1a(R*),3ab,4E(1S*,3R*,5Z),7aa]]- 1a,25-Dihydroxy-22-oxavitamin D3 22-Oxa-1,25-dihydroxyvitamin D3 22-Oxa-1a,25-dihydroxyvitamin D3 22-Oxacalcitriol MC 1275 OCT (steroid) Oxarol Cholecaciferol 3b-Hydroxy-5,7-Cholestadien 5,7-Cholestadien-3b-Ol CHOLECALCIFEROL (D3) 100MG NEAT Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)- Vitamin d3, 99+%, crystalline Vitamin D3, crystalline 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol VITAMIN D3(CHOLECALCIFEROL)(USP)(P)