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Cafedrine

Cafedrine structure

CAS No.: 58166-83-9

Chemical Name:: Cafedrine

Synonyms: Cafedrine;Cafedrina;Brn 0583473;l-Cafedrine;(-)-Cafedrine;Cafedrina [inn-spanish];7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline;7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline;7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione

CBNumber:: CB01178203

Molecular Formula:: C18H23N5O3

Molecular Weight:: 357.412

MDL Number:: MFCD00865826

MOL File:: 58166-83-9.mol

Last updated:2022-12-21 16:56:50

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Cafedrine Properties

Boiling point	591.6±52.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
pka	13.90±0.20(Predicted)
FDA UNII	0UYY5V4U2Q
ATC code	C01CA21

Cafedrine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C799035	(-)-Cafedrine	58166-83-9	5mg	$50	2021-12-16	Buy
American Custom Chemicals Corporation	API0010919	CAFEDRINE 95.00%	58166-83-9	5MG	$497.41	2021-12-16	Buy

Product number	Packaging	Price	Buy
C799035	5mg	$50	Buy
API0010919	5MG	$497.41	Buy

Cafedrine Chemical Properties,Uses,Production

Originator

Praxinor,Merck Lipha Sante

Uses

(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.

Manufacturing Process

7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of 7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.

Therapeutic Function

Analeptic

Cafedrine Preparation Products And Raw materials

Raw materials

Preparation Products

Cafedrine Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58
United States Biological	--	sales@advtechind.com	United States	6106	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
United States Biological	58

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Cafedrine Fenethylline 7-(2-aminoethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione

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Cafedrine 3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 7-(2-((Alphas,betar)-beta-hydroxy-alpha-methylphenethylamino)ethyl)-1,3-dimethyl-2,6(1H,3H)purindion 7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline Brn 0583473 Cafedrina Cafedrina [inn-spanish] 7-(2-{[(1R,2S)-1-Hydroxy-1-phenyl-2-propanyl]amino}ethyl)-1,3-dim ethyl-3,7-dihydro-1H-purine-2,6-dione 1H-Purine-2,6-dione, 3,7-dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl- (-)-Cafedrine l-Cafedrine 58166-83-9