CYCLO(-PRO-VAL)
- CAS No.
- 2854-40-2
- Chemical Name:
- CYCLO(-PRO-VAL)
- Synonyms
- Cyclo(Val-Pro);CYCLO(-PRO-VAL);Cyclo(L-Val-L-Pro-);Cyclo(L-Pro-L-Val-);2854-40-2/5654-87-5;Cyclo(L-prolyl-L-valyl);CYCLO(L-PROLYL-L-VALINE);Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL);(3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
- CBNumber:
- CB0132749
- Molecular Formula:
- C10H16N2O2
- Molecular Weight:
- 196.25
- MDL Number:
- MFCD03093469
- MOL File:
- 2854-40-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
CYCLO(-PRO-VAL) price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27961 | Cyclo(L-Pro-L-Val) | 2854-40-2 | 25mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 27961 | Cyclo(L-Pro-L-Val) | 2854-40-2 | 50mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 27961 | Cyclo(L-Pro-L-Val) | 2854-40-2 | 100mg | $129 | 2024-03-01 | Buy |
| Cayman Chemical | 27961 | Cyclo(L-Pro-L-Val) | 2854-40-2 | 250mg | $283 | 2024-03-01 | Buy |
| TRC | C989825 | Cyclo(L-prolyl-L-valyl) | 2854-40-2 | 25mg | $335 | 2021-12-16 | Buy |
CYCLO(-PRO-VAL) Chemical Properties,Uses,Production
Description
Cyclo(L-Pro-L-Val) is a diketopiperazine that has been found in the marine sponge T. ignis, the bacterium B. pumilus, and the fungus A. fumigatus, among others. It is active against the bacteria S. aureus and B. subtilis (MICs = 16.3 and 18.2 μg/ml, respectively) but not E. coli (MIC = >20 μg/ml). Cyclo(L-Pro-L-Val) inhibits activation of a LuxR-dependent E. coli biosensor by the quorum-sensing molecule 3-oxo-hexanoyl-homoserine lactone (IC50 = 0.4 mM) and activates violacein pigment production in the LuxR-dependent C. violaceum acyl homoserine lactone reporter strain CV026. However, it does not activate or inhibit lacZ-based reporter fusions in S. liquefaciens or A. tumefaciens.
Uses
Cyclo(L-prolyl-L-valyl) is a metabolite found in various marine fungi and bacteria. It is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.
Uses
Cyclo(L-Pro-L-Val) is a diketopiperazine formed by the fusion of valine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Val) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of the cyclo(L-Pro-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.
Definition
ChEBI: Cyclo(L-Pro-L-Val) is a piperazinone. It has a role as a metabolite.
CYCLO(-PRO-VAL) Preparation Products And Raw materials
CYCLO(-PRO-VAL) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19918 | 55 |