(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol

CAS No.
2128-61-2
Chemical Name:
(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol
Synonyms
Sparsiflorine;(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol;4H-Dibenzo[de,g]quinoline-1,10-diol, 5,6,6a,7-tetrahydro-2-methoxy-, (6aS)-
CBNumber:
CB02142065
Molecular Formula:
C17H17NO3
Molecular Weight:
283.32
MDL Number:
MOL File:
2128-61-2.mol
Last updated:2022-12-21 16:56:50

(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol Properties

Melting point 230-232 °C (decomp)
Boiling point 528.0±50.0 °C(Predicted)
Density 1.320±0.06 g/cm3(Predicted)
pka 9?+-.0.20(Predicted)
FDA UNII 53EWB5GJ52

(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol Chemical Properties,Uses,Production

Description

The leaves of Croton sparsijlorus Morung yield this noraporphine alkaloid which crystallizes as colourless, slender needles from EtOH. Two hydroxyl groups and an imino group are present and the base yields crystalline salts and derivatives, e.g. the hydrochloride, [α]30D + 43° (H20); methiodide, m.p. 218°C (dec.); the O,N-diacetyl derivative, m.p. 245°C and the triacetyl derivative, m.p. 196-7°C. The N-methyl compound gives a crystalline methiodide, m.p. 236-8°C (dec.). The structure has been established as 2-methoxy-l : 10-dihydroxynor aporphine.

References

Chatterjee et al., Tetrahedron Lett., 1539 (1965)

(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol Preparation Products And Raw materials

Raw materials

Preparation Products

(6aS)-5,6,6a,7-Tetrahydro-2-methoxy-4H-dibenzo[de,g]quinoline-1,10-diol Sparsiflorine 4H-Dibenzo[de,g]quinoline-1,10-diol, 5,6,6a,7-tetrahydro-2-methoxy-, (6aS)- 2128-61-2