ChemicalBook >> CAS DataBase List >>BTSA 1
BTSA 1
- CAS No.
- 314761-14-3
- Chemical Name:
- BTSA 1
- Synonyms
- BTSA 1;CS-2853;BTSA 1;BTSA-1;BTSA1 >=98% (HPLC);5-Phenyl-2-(4-phenyl-thiazol-2-yl)-4-(thiazol-2-yl-hydrazono)-2,4-dihydro-pyrazol-3-one;1H-Pyrazole-4,5-dione, 3-phenyl-1-(4-phenyl-2-thiazolyl)-, 4-[2-(2-thiazolyl)hydrazone];5-Phenyl-2-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-2,4-dihydro-3H-pyrazol-3-one;inhibit,FITC-BIM,caspase-3/7,translocation,Bcl-2 Family,viability,Inhibitor,BTSA1,mitochondrial,pharmacologically,BAX,AML,BTSA 1,BTSA-1,SAHBA2,Apoptosis
- CBNumber:
- CB03374627
- Molecular Formula:
- C21H14N6OS2
- Molecular Weight:
- 430.51
- MDL Number:
- MOL File:
- 314761-14-3.mol
Last updated:2023-09-04 15:51:00
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
BTSA 1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Crysdot | CD31005001 | BTSA1 98% | 314761-14-3 | 2mg | $86 | 2021-12-16 | Buy |
| Crysdot | CD31005001 | BTSA1 98% | 314761-14-3 | 5mg | $158 | 2021-12-16 | Buy |
| Crysdot | CD31005001 | BTSA1 98% | 314761-14-3 | 10mg | $313 | 2021-12-16 | Buy |
| Crysdot | CD31005001 | BTSA1 98% | 314761-14-3 | 25mg | $514 | 2021-12-16 | Buy |
| DC Chemicals | 012494 | BTSA1 | 314761-14-3 | 001 | $700 | 2021-12-16 | Buy |
BTSA 1 Chemical Properties,Uses,Production
Biological Activity
BTSA1 is a BAX activator that binds to its N-terminal activation site with high affinity and specificity, induces a conformational change in BAX, and causes BAC-mediated apoptosis. It efficiently promotes apoptosis in leukemia cell lines and patient samples without affecting healthy cells.
in vivo
BTSA1 effectively inhibits human acute myeloid leukemia xenografts and enhances host survival without toxic side effects. In mice, it was well tolerated.
target
| Target | Value | ||||
| Bax () |
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Naturewill Biotechnology Co., Ltd. | 18113192475 18113192475 | 3157321941@qq.com | China | 5000 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4153 | 55 | |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 646 | 55 |
| Hui Chem Co., Ltd. | 021-34799779 18918539052 | 1879902218@qq.com | China | 77 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
BTSA1 >=98% (HPLC)
1H-Pyrazole-4,5-dione, 3-phenyl-1-(4-phenyl-2-thiazolyl)-, 4-[2-(2-thiazolyl)hydrazone]
CS-2853
5-Phenyl-2-(4-phenyl-thiazol-2-yl)-4-(thiazol-2-yl-hydrazono)-2,4-dihydro-pyrazol-3-one
BTSA 1;BTSA-1
BTSA 1
inhibit,FITC-BIM,caspase-3/7,translocation,Bcl-2 Family,viability,Inhibitor,BTSA1,mitochondrial,pharmacologically,BAX,AML,BTSA 1,BTSA-1,SAHBA2,Apoptosis
5-Phenyl-2-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-2,4-dihydro-3H-pyrazol-3-one
314761-14-3
C21H14N6OS2
API