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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

CAS No.
104375-88-4
Chemical Name:
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
Synonyms
DMT-5-I-dU;DMT-5-I-2'-deoxyuridine;5'-DMT-5-I-2'-deoxyuridine;5'-DMT-5-iodo-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMT-5-iodo-2'-deoxyuridine;5'-O-DMTr-5-Iodo-2'-deoxyuridine;5’-O-DMTr-5-iodo-2’-deoxyuridine;5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine;5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE
CBNumber:
CB0426433
Molecular Formula:
C30H29IN2O7
Molecular Weight:
656.46
MDL Number:
MFCD01631069
MOL File:
104375-88-4.mol
MSDS File:
SDS
Last updated:2024-02-23 10:06:30

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Properties

Melting point >128 °C (decomp)
Density 1.60±0.1 g/cm3(Predicted)
pka 7.94±0.10(Predicted)
InChIKey RLDUYGSOCGOJTP-SKDNVIITNA-N
SMILES C(OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C(=O)NC2=O)I)O1)(C1C=CC=CC=1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,4,7,r|

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D233065 2’-Deoxy-5’-O-DMT-5-iodouridine 104375-88-4 250mg $165 2021-12-16 Buy
Biosynth Carbosynth ND08238 2'-Deoxy-5'-O-DMT-5-iodouridine 104375-88-4 1g $230 2021-12-16 Buy
AK Scientific 3467CS 2'-Deoxy-5'-O-DMT-5-iodouridine 104375-88-4 1g $360 2021-12-16 Buy
Biosynth Carbosynth ND08238 2'-Deoxy-5'-O-DMT-5-iodouridine 104375-88-4 2g $360 2021-12-16 Buy
American Custom Chemicals Corporation NUC0001525 2'-DEOXY-5'-O-DMT-5-IODOURIDINE 95.00% 104375-88-4 5MG $502.67 2021-12-16 Buy
Product number Packaging Price Buy
D233065 250mg $165 Buy
ND08238 1g $230 Buy
3467CS 1g $360 Buy
ND08238 2g $360 Buy
NUC0001525 5MG $502.67 Buy

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Chemical Properties,Uses,Production

Description

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.

Uses

2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Preparation Products And Raw materials

Raw materials

Preparation Products

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 28761 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
NewCan Biotech Limited
+86-0571-86912261 +8613735419629 sales@newcanbio.com China 10026 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE 5''-O-(DIMETHOXYTRITYL)-5-IODO-2''-DEOXYURIDINE 99% 5'-DMT-5-iodo-deoxyuridine 2'-Deoxy-5'-O-DMT-5-iodouridine DMT-5-I-dU 5'-O-DMTr-5-Iodo-2'-deoxyuridine 5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine 5'-O-(4,4'-Dimethoxytrityl)-5-Iodo-2'-deoxyuridine 5'-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine 5'-DMT-5-I-2'-deoxyuridine DMT-5-I-2'-deoxyuridine 5'-O-DMT-5-iodo-2'-deoxyuridine 5-Iodo-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxyuridine Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-iodo- 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE USP/EP/BP 1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine 1-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxyoxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine 5’-O-DMTr-5-iodo-2’-deoxyuridine 104375-88-4 C30H29IN2O7