1-ethyl-1H-pyrazol-4-amine
- CAS No.
- 876343-24-7
- Chemical Name:
- 1-ethyl-1H-pyrazol-4-amine
- Synonyms
- 1-ethylpyrazol-4-amine;4-Amino-1-ethylpyrazole;1-ethyl-1H-pyrazol-4-amine;4-Amino-1-ethyl-1H-pyrazole;1H-Pyrazol-4-amine, 1-ethyl-;1-ethyl-1H-pyrazol-4-amine hydrochloride;1-ethyl-1H-pyrazol-4-amine(SALTDATA: HCl)
- CBNumber:
- CB11532949
- Molecular Formula:
- C5H9N3
- Molecular Weight:
- 111.15
- MDL Number:
- MFCD05861667
- MOL File:
- 876343-24-7.mol
- MSDS File:
- SDS
| Boiling point | 238.6±13.0 °C(Predicted) |
|---|---|
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 3.72±0.10(Predicted) |
| CAS DataBase Reference | 876343-24-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P312 |
| HazardClass | IRRITANT |
| HS Code | 2933199090 |
1-ethyl-1H-pyrazol-4-amine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 3909AC | 1-Ethyl-1H-pyrazol-4-amine | 876343-24-7 | 250mg | $103 | 2021-12-16 | Buy |
| AK Scientific | 3909AC | 1-Ethyl-1H-pyrazol-4-amine | 876343-24-7 | 1g | $136 | 2021-12-16 | Buy |
| BroadPharm | BP-21178 | 1-ETHYL-1H-PYRAZOL-4-AMINE | 876343-24-7 | 500mg | $150 | 2021-12-16 | Buy |
| Matrix Scientific | 034033 | 1-Ethyl-1H-pyrazol-4-ylamine hydrochloride | 876343-24-7 | 500mg | $195 | 2021-12-16 | Buy |
| Apolloscientific | OR110643 | 4-Amino-1-ethyl-1H-pyrazole | 876343-24-7 | 1g | $225 | 2021-12-16 | Buy |
1-ethyl-1H-pyrazol-4-amine Chemical Properties,Uses,Production
Uses
1-ethyl-1H-pyrazol-4-amine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
General Procedure for the Synthesis of 4-Amino-l-N-alkylated-pyrazolesA solution of 4-nitropyrazole (300mg, 2.65mmol), potassium carbonate (2eq) and the alkylating reagent (l .leq) in acetonitrile (lOmL) was heated at 60??C for 18h. After cooling to rt the mixture was diluted with EtOAc and washed with water. The organic phase was collected, dried (MgS04) and concentrated in vacuo. The crude residue was dissolved in methanol (lOmL), palladium on carbon (50mg) was added and the reaction was stirred under a balloon of hydrogen for 18h. The resulting mixture was filtered through Celite and the filtrate concentrated in vacuo to give the desired product. Procedure B:Example 11: 2-((6-( 1 -Ethyl- 1 H-pyrazo 1-4-ylamino)- 1 H-pyrazo lo [3 ,4-d]pyrimidin- 1 -yl) methyl)benzonitrileThe following compound was made according to the procedure in Example 1, using 1-ethyl- lH-pyrazo 1-4-amine. 1 -ethyl- lH-pyrazol-4-amine was prepared by Procedure A using ethyl iodide as alkylating agent: 1H NMR (d6-DMSO) |? 9.94 (s, 1H), 8.94 (s, 1H), 8.10 (s, 2H), 7.91 (dd, 1H), 7.66 (td, 1H), 7.49-7.53 (m, 2H), 7.35-7.37 (m, 1H), 5.76 (s, 2H), 4.11 (q, 2H), 1.35 (t, 3H); LC-MS method B, (ES+) 345.1, RT = 8.58min.
1-ethyl-1H-pyrazol-4-amine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Medfine Bio-pharmaceutical Co., Ltd | +8619921460217 | tina.lv@bio-medfine.com | China | 201 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |