ChemicalBook >> CAS DataBase List >>AC-IETD-AFC
AC-IETD-AFC
- CAS No.
- 211990-57-7
- Chemical Name:
- AC-IETD-AFC
- Synonyms
- AC-IETD-AFC;AC-ILE-GLU-THR-ASP-AFC;Caspase 8 Substrate 1f;CGUOWXRXLQXOKO-FCQBACSVSA-N;M.W. 729.66 C31H38F3N5O12;CASPASE-8 FLUOROGENIC SUBSTRATE;CASPASE 8 SUBSTRATE 1F, FLUOROGENIC;GRANZYME B SUBSTRATE I, COLORIMETRIC;AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)
- CBNumber:
- CB1395556
- Molecular Formula:
- C31H38F3N5O12
- Molecular Weight:
- 729.65
- MDL Number:
- MFCD02094703
- MOL File:
- 211990-57-7.mol
Last updated:2023-04-23 13:52:06
AC-IETD-AFC price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J64258 | N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin | 211990-57-7 | 5mg | $161 | 2021-12-16 | Buy |
| Cayman Chemical | 17480 | Ac-IETD-AFC ≥95% | 211990-57-7 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17480 | Ac-IETD-AFC ≥95% | 211990-57-7 | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 17480 | Ac-IETD-AFC ≥95% | 211990-57-7 | 10mg | $321 | 2024-03-01 | Buy |
| TRC | A795613 | Ac-IETD-AFC | 211990-57-7 | 5mg | $145 | 2021-12-16 | Buy |
AC-IETD-AFC Chemical Properties,Uses,Production
Uses
N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin is a fluorogenic substrate for caspases -6, -8, and -10. The IETD sequence is based on the procaspase-3 cleavage site. Residues 172-175 of procaspase-3 are cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.
Uses
Ac-IETD-AFC is a fluorogenic substrate for caspase-8/caspase-3 processing enzyme and granzyme B. It is also a substrate for caspase-10. The IETD sequence is based on caspase-3 proenzyme cleavage site.
AC-IETD-AFC Preparation Products And Raw materials
Raw materials
Preparation Products
AC-IETD-AFC Suppliers
Global( 75)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Beijing Ouhe Technology Co., Ltd | 010-82967028 13552068683 | 2355560935@qq.com | China | 12458 | 60 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-021-20242659 18930833303 | order@changyanchem.com | China | 5008 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973186 4009686088 | 3193328036@qq.com | China | 18352 | 68 |
| Nanjing Leon Biological Technology Co., Ltd. | 17705183659 | sales@njleonbiotech.com | China | 5503 | 55 |
View Lastest Price from AC-IETD-AFC manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-03-06 | AC-IETD-AFC
211990-57-7
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
-
- AC-IETD-AFC
211990-57-7
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co
211990-57-7(AC-IETD-AFC)Related Search:
CASPASE 8 SUBSTRATE 1F, FLUOROGENIC
CASPASE-8 FLUOROGENIC SUBSTRATE
GRANZYME B SUBSTRATE I, COLORIMETRIC
AC-IETD-AFC
AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN
AC-ILE-GLU-THR-ASP-AFC
N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)
N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC
M.W. 729.66 C31H38F3N5O12
N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine
CGUOWXRXLQXOKO-FCQBACSVSA-N
Caspase 8 Substrate 1f
L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
Ac-IETD-AFC (N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin)
211990-57-7
Caspase/Related Products
peptide
Caspases/Apoptosis