Fumaryl chloride
- CAS No.
- 627-63-4
- Chemical Name:
- Fumaryl chloride
- Synonyms
- tl189;TL 189;fumaryl;FumarylChoride;Fumarylchlorid;FUMARYL CHLORIDE;fumaroylchloride;Fumaroyl chloride;FUMARYL DICHLORIDE;chloruredefumaryle
- CBNumber:
- CB1854022
- Molecular Formula:
- C4H2Cl2O2
- Molecular Weight:
- 152.96
- MDL Number:
- MFCD00000733
- MOL File:
- 627-63-4.mol
- MSDS File:
- SDS
| Melting point | -2 °C |
|---|---|
| Boiling point | 161-164 °C(lit.) |
| Density | 1.415 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 165 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Clear yellow |
| Specific Gravity | 1.415 (20/4℃) |
| Water Solubility | decomposes |
| Sensitive | Moisture Sensitive |
| BRN | 1721342 |
| InChIKey | ZLYYJUJDFKGVKB-OWOJBTEDSA-N |
| CAS DataBase Reference | 627-63-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | B95L4812RG |
| NIST Chemistry Reference | Fumaryl chloride(627-63-4) |
| EPA Substance Registry System | 2-Butenedioyl dichloride, (2E)- (627-63-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302+H312-H314 | |||||||||
| Precautionary statements | P260-P280-P301+P312+P330-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 20/21/22-34-37-29-36/37-14 | |||||||||
| Safety Statements | 26-36/37/39-45-8-27 | |||||||||
| RIDADR | UN 1780 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LT2800000 | |||||||||
| F | 21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29171990 | |||||||||
| NFPA 704 |
|
Fumaryl chloride price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 151386 | Fumaryl chloride 95% | 627-63-4 | 25g | $72.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 151386 | Fumaryl chloride 95% | 627-63-4 | 5g | $26 | 2022-05-15 | Buy |
| TCI Chemical | F0152 | Fumaryl Chloride >95.0%(GC)(T) | 627-63-4 | 25g | $47 | 2024-03-01 | Buy |
| TCI Chemical | F0152 | Fumaryl Chloride >95.0%(GC)(T) | 627-63-4 | 500g | $387 | 2024-03-01 | Buy |
| Alfa Aesar | A14540 | Fumaryl chloride, 95% | 627-63-4 | 25g | $45.65 | 2024-03-01 | Buy |
Fumaryl chloride Chemical Properties,Uses,Production
Chemical Properties
Clear yellow liquid
Uses
Chemical intermediate for pharmaceuticals, dyestuffs, and insecticides.
Uses
Fumaryl chloride was used in the preparation of high molecular weight poly(propylene fumarate). The photodissociation dynamics of fumaryl chloride was studied. It is used in agrochemicals and pharmaceuticals manufacturing. Also used as an intermediate for dyes, textile auxiliaries and peroxide compounds. It is an acid halide building block.
Preparation
Fumaryl chloride has been prepared from fumaric acid and phthaloyl chloride, from maleic acid by the action of thionyl chloride in the presence of zinc chloride, and from maleic anhydride by the use of phthaloyl chloride in the presence of zinc chloride.
Org. Synth. 1940, 20, 51
DOI: 10.15227/orgsyn.020.0051
General Description
Fumaryl chloride appears as a straw colored fuming liquid with a pungent odor. Vapors irritate the eyes and mucous membranes. Corrosive to metals and tissue.
Reactivity Profile
Fumaryl chloride is incompatible with strong oxidizing agents, alcohols, amines and other bases. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Hazard
Corrosive to eyes and skin.
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Safety Profile
Moderately toxic by ingestion, inhalation, and skin contact. A skin, eye, and mucous membrane irritant. A corrosive agent. Will react with water or steam to produce toxic and corrosive fumes. When heated to decomposition it emits highly toxic fumes of phosgene and HCl.
Fumaryl chloride Preparation Products And Raw materials
Raw materials
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Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Rionlon ( Tianjin ) Pharmaceutical Co., Ltd. | 0086-13512289226 | yangli@rionlon.com | CHINA | 28 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 | |
| Aston Chemical | 13000000000 | sales@astonchem.com | United States | 1634 | 58 |
| LUYUNJIA CHEMISTRY XIAMEN LIMITED | +86-592-5360779 +86-13055435203 | China | 5996 | 58 |
View Lastest Price from Fumaryl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | Fumaryl chloride
627-63-4
|
US $6.60 / KG | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
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- Fumaryl chloride
627-63-4
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co