A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE

CAS No.
25441-16-1
Chemical Name:
A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE
Synonyms
CINNAMEDRINE HYDROCHLORIDE;DL-Cinnamedrine hydrochloride;CINNAMYLEPHEDRIN HYDROCHLORIDE;PHENYL-2-(N-CINNAMYL-N-METHYLAMINO)PROPANOL HYDROCHLORIDE;(±)-α-[1-(Cinnamylamino)ethyl]benzyl alcohol hydrochloride;A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE;(±)-cinnamyl(2-hydroxy-1-methyl-2-phenylethyl)methylammonium chloride
CBNumber:
CB2171465
Molecular Formula:
C19H24ClNO
Molecular Weight:
317.85
MDL Number:
MFCD00014400
MOL File:
25441-16-1.mol

A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE Properties

Melting point 175 °C
FDA UNII T4B6SPQ0UF

A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE Chemical Properties,Uses,Production

Originator

Midol Tab,Sterling Winthrop

Manufacturing Process

8.0 g of 1-phenyl-2-methylaminopropanol-1 are dissolved in 30 ml of warm benzene and the solution is mixed with 5.0 g of cinnamylbromide. It isallowed to stand for 2 h at room temperature; the whole is then filtered with suction to eliminate the phenylmethylaminopropanol hydrobromide formed and the filtrate is shaken out with dilute hydrochloric acid, while adding such a quantity of water that the thick oil drops which separate are dissolved. The aqueous extract is filtered until it is clear, rendered alkaline by means of ammonia, shaken with ether, the ether is distilled off, the residue is recrystalized, so 1-phenyl-2-methyl-cinnamylaminopropanol-1 was obtained.
In practice it is usually used as hydrochloride.

Therapeutic Function

Smooth muscle relaxant

A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE Preparation Products And Raw materials

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PHENYL-2-(N-CINNAMYL-N-METHYLAMINO)PROPANOL HYDROCHLORIDE A-[1-(CINNAMYLMETHYLAMINO)ETHYL]BENZYL ALCOHOL HYDROCHLORIDE CINNAMEDRINE HYDROCHLORIDE CINNAMYLEPHEDRIN HYDROCHLORIDE (±)-cinnamyl(2-hydroxy-1-methyl-2-phenylethyl)methylammonium chloride (±)-α-[1-(Cinnamylamino)ethyl]benzyl alcohol hydrochloride DL-Cinnamedrine hydrochloride 25441-16-1