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SENEGENIN
- CAS No.
- 2469-34-3
- Chemical Name:
- SENEGENIN
- Synonyms
- SENEGIN;SENEGENIN;Tenuigenin;Tenuifgenin;Tenuifolic acid;Senegenin (6CI);Senegenin, >=98%;12-(Chloromethyl)-2,3-dihydroxy-27-norolean-13-ene-23,28-dioic acid;12α-Chloromethyl-2β,3β-dihydroxy-27-norolean-1-ene-23,28-dioic acid;28-dioicacid,12-(chloromethyl)-2-beta,3-beta-dihydroxy-27-noro-13-ene-2
- CBNumber:
- CB2222527
- Molecular Formula:
- C30H45ClO6
- Molecular Weight:
- 537.13
- MDL Number:
- MFCD00466906
- MOL File:
- 2469-34-3.mol
- MSDS File:
- SDS
Last updated:2023-08-22 11:49:44
| Melting point | 290-292℃ |
|---|---|
| alpha | D +19° (c = 0.70 in ethanol) |
| Boiling point | 674.1±55.0 °C(Predicted) |
| Density | 1.28 |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble10mg/mL, clear |
| pka | 4.27±0.70(Predicted) |
| form | powder |
| color | white to beige |
| FDA UNII | 06S1QH951L |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | RC8815000 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 3mg/kg | |||||||||
| NFPA 704 |
|
SENEGENIN price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1001 | Senegenin ≥98% (HPLC) | 2469-34-3 | 5mg | $96 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1001 | Senegenin ≥98% (HPLC) | 2469-34-3 | 25mg | $464 | 2023-06-20 | Buy |
| Cayman Chemical | 28824 | Tenuigenin | 2469-34-3 | 5mg | $75 | 2024-03-01 | Buy |
| Cayman Chemical | 28824 | Tenuigenin | 2469-34-3 | 100mg | $975 | 2024-03-01 | Buy |
| Cayman Chemical | 28824 | Tenuigenin | 2469-34-3 | 10mg | $143 | 2024-03-01 | Buy |
SENEGENIN Chemical Properties,Uses,Production
Description
Tenuigenin is a triterpenoid sapogenin that has been found in P. tenuifolia and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. It inhibits IL-1β and reactive oxygen species (ROS) production from LPS-induced mouse BV2 microglia at a concentration of 4 μM. Tenuigenin (25 mg/kg per day) decreases NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation and prevents dopaminergic neuronal degeneration in the mouse substantia nigra pars compacta in an MPTP-induced model of Parkinson''s disease. Tenuigenin (2 mg/kg) also reduces increases in lung edema and the levels of IL-1β and TNF-α in bronchoalveolar lavage fluid (BALF) in a mouse model of intranasal S. aureus-induced pneumonia.
Uses
Tenuifgenin is a Chinese herbal extract with anti-oxidative and anti-inflammatory effects involving toxin induced cell models of Parkinson’s disease.
Definition
ChEBI: Senegenin is a 12alpha-hydroxy steroid.
SENEGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 177)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from SENEGENIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | SENEGENIN
2469-34-3
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2023-02-24 | Senegenin
2469-34-3
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2023-02-24 | Senegenin
2469-34-3
|
US $0.00 / mg | 5mg | Analytical Standard | 10 g | Shanghai Standard Technology Co., Ltd. |
2469-34-3(SENEGENIN)Related Search:
SENEGENIN
SENEGIN
28-dioicacid,12-(chloromethyl)-2-beta,3-beta-dihydroxy-27-noro-13-ene-2
27-Norolean-13-ene-23,28-dioicacid, 12-(chloromethyl)-2,3-dihydroxy-, (2β,3β,4α,12α)-
Tenuigenin
12α-(Chloromethyl)-2β,3β-dihydroxy-27-nor-5α-olean-13-ene-23,28-dioic acid
12α-Chloromethyl-2β,3β-dihydroxy-27-norolean-1-ene-23,28-dioic acid
Tenuifolic acid
(2beta,3beta,4alpha,12alpha)-12-(Chloromethyl)-2,3-dihydroxy-27-norolean-13-ene-23,28-dioic acid
12-(Chloromethyl)-2,3-dihydroxy-27-norolean-13-ene-23,28-dioic acid
Senegenin, >=98%
13-(chloromethyl)-2,3-dihydroxy-4,6a,11,11,14b-pentamethyl-2,3,4a,5,6,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picene-4,8a-dicarboxylic acid
Tenuifgenin
(2S,3R,4S,4aR,6aR,8aS,12aS,13S,14aR,14bR)-13-(chloromethyl)-2,3-dihydroxy-4,6a,11,11,14b-pentamethyl-2,3,4a,5,6,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picene-4,8a-dicarboxylic acid
13-(Chloromethyl)-2,3-dihydroxy-4,6a,11,11,14b-pentamethyl-2,3,4,4a,5,6,6a,7,8,9,10,11,12,12a,13,14,14a,14b-octadecahydro-4,8a(1H)-picenedicarboxylic acid
Senegenin (6CI)
2469-34-3
C30H45ClO6
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract