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β-Gal-NONOate

β-Gal-NONOate Structure
β-Gal-NONOate structure
CAS No.
357192-77-9
Chemical Name:
β-Gal-NONOate
Synonyms
β-Gal-NONOate;β-Gal-NONOate;β-D-Galactopyranose, 1-O-[2-oxido-2-(1-pyrrolidinyl)diazenyl]-;(E)-oxido-pyrrolidin-1-yl-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyiminoazanium
CBNumber:
CB22592909
Molecular Formula:
C10H19N3O7
Molecular Weight:
293.27
MDL Number:
MFCD09951895
MOL File:
357192-77-9.mol
Last updated:2023-04-23 13:52:06
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β-Gal-NONOate Properties

solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form A crystalline solid

β-Gal-NONOate price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10009137 β-Gal-NONOate ≥98% 357192-77-9 1mg $37 2024-03-01 Buy
Cayman Chemical 10009137 β-Gal-NONOate ≥98% 357192-77-9 5mg $151 2024-03-01 Buy
Cayman Chemical 10009137 β-Gal-NONOate ≥98% 357192-77-9 10mg $283 2024-03-01 Buy
Product number Packaging Price Buy
10009137 1mg $37 Buy
10009137 5mg $151 Buy
10009137 10mg $283 Buy

β-Gal-NONOate Chemical Properties,Uses,Production

Description

β-Gal-NONOate is a nitric oxide (NO) donor which releases NO following activation by β-galactosidase.1 β-Gal-NONOate is stable in aqueous solution at neutral and acidic pH for several hours, exhibits good water solubility, and is able to cross the cell membrane. Following enzymatic hydrolysis, β-Gal-NONOate decomposes with a half-life of six minutes at pH 5.6.1 β-Gal-NONOate is cytotoxic to a number of cancer cell-lines and exhibits high bactericidal activity against E. coli transformed with the β-galactosidase gene.1,2

References

1. Wu, X., Tang, X., Xian, M., et al. Glycosylated diazeniumdiolates: A novel class of enzyme-activated nitric oxide donors Tetrahedron Lett. 42(23),3779-3782(2001).
2. Chen, C., Shi, Y.Q., Song, J., et al. Delivery of nitric oxide released from β-Gal-NONOate activation by β-galactosidase and its activity against Escherichia coli Biol. Pharm. Bull. 29(6),1239-1241(2006).

β-Gal-NONOate Preparation Products And Raw materials

Raw materials

Preparation Products

β-Gal-NONOate Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
β-Gal-NONOate (E)-oxido-pyrrolidin-1-yl-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyiminoazanium β-D-Galactopyranose, 1-O-[2-oxido-2-(1-pyrrolidinyl)diazenyl]- β-Gal-NONOate 357192-77-9