Methylprednisolone aceponate
- CAS No.
- 86401-95-8
- Chemical Name:
- Methylprednisolone aceponate
- Synonyms
- SH-440;Advantan;ZK-91588;ZK-91-588;Aceponate;ZK-91588：SH-440;Prednisolone Impurity 21;METHYLPREDNISOLONE ACEPONATE;Methilprednisolone aceponate;Methylprednisolone Impurity 55
- CBNumber:
- CB2483146
- Molecular Formula:
- C27H36O7
- Molecular Weight:
- 472.57
- MDL Number:
- MFCD00866150
- MOL File:
- 86401-95-8.mol
| Melting point | 105 - 108°C |
|---|---|
| Boiling point | 595.8±50.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Ethyl Acetate(Slightly) |
| form | Solid |
| pka | 14.05±0.70(Predicted) |
| color | White to Off-White |
| InChIKey | DALKLAYLIPSCQL-TXWHWSFMNA-N |
| SMILES | O(C(CC)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@]12C)O)=O |&1:5,15,16,18,25,27,28,30,r| |
| FDA UNII | ET54W9J4U2 |
| ATC code | D07AC14 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
Methylprednisolone aceponate price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M325725 | 6α-MethylPrednisoloneAceponate | 86401-95-8 | 250mg | $785 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003341 | METHYLPREDNISOLONE ACEPONATE 95.00% | 86401-95-8 | 25MG | $716.1 | 2021-12-16 | Buy |
| Matrix Scientific | 093984 | Methylprednisolone aceponate 95+% | 86401-95-8 | 250mg | $756 | 2021-12-16 | Buy |
| AK Scientific | K542 | Methylprednisoloneaceponate | 86401-95-8 | 250mg | $1070 | 2021-12-16 | Buy |
| Matrix Scientific | 093984 | Methylprednisolone aceponate 95+% | 86401-95-8 | 1g | $1647 | 2021-12-16 | Buy |
Methylprednisolone aceponate Chemical Properties,Uses,Production
Description
Methylprednisolone aceponate (MPA) is a new potent topical corticosteroid. Chemically, it is a corticosteroid diester that penetrates the skin rapidly. It is rapidly metabolised and then conjugated, so although potent, it does not appear to cause serious local or systemic side effects. Clinical trials have shown that once daily use is sufficient to control most eczematous conditions and is also appropriate and effective in atopic dermatitis. MPA is effective in the treatment of facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis. MPA is also suitable for use in children and infants. MPA is available in a wide range of formulations (0.1%) including creams, ointments, fat ointments, lotions and solutions depending on the patient's individual condition.
Uses
Methylprednisolone aceponate used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.
Definition
ChEBI: Methylprednisolone aceponate is a corticosteroid hormone.
Trade name
ADVANTAN?
Side effects
The most common side effects of Methylprednisolone aceponate (MPA) include itching and burning sensation. Other rare side effects are skin infection at the application site, redness, swelling or irritation at the application site, skin infection or the appearance of small blood vessels on the surface, stretch marks, acne, infection of the hair follicles at the application site, excessive growth of unwanted hair, discolouration of the skin and allergic reactions. If any serious adverse reaction occurs, contact your doctor promptly.
Methylprednisolone aceponate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9635 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 968 | 58 | |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from Methylprednisolone aceponate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-09-29 | Methylprednisolone aceponate
86401-95-8
|
US $0.00 / Kg/Bag | 10g | 98%-102% | 10kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-07-02 | Methylprednisolone aceponate
86401-95-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-03-17 | Methylprednisolone aceponate
86401-95-8
|
US $60.00 / KG | 1g | 99.8% | 10tons | Hebei shuoxi biotechnology co. LTD |
-
- Methylprednisolone aceponate
86401-95-8
- US $0.00 / Kg/Bag
- 98%-102%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Methylprednisolone aceponate
86401-95-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Methylprednisolone aceponate
86401-95-8
- US $60.00 / KG
- 99.8%
- Hebei shuoxi biotechnology co. LTD