Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-P-ANISYL-1,3-INDANDIONE

2-P-ANISYL-1,3-INDANDIONE

2-P-ANISYL-1,3-INDANDIONE Structure
2-P-ANISYL-1,3-INDANDIONE structure
CAS No.
117-37-3
Chemical Name:
2-P-ANISYL-1,3-INDANDIONE
Synonyms
andion;Miradon;spe2792;Unidone;SPE 2792;unidione;HSDB 3205;Andindione;Anisindone;nisindione
CBNumber:
CB2689681
Molecular Formula:
C16H12O3
Molecular Weight:
252.26
MDL Number:
MFCD00176194
MOL File:
117-37-3.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00
Request For Quotation

2-P-ANISYL-1,3-INDANDIONE Properties

Melting point 156-157°
Boiling point 355.44°C (rough estimate)
Density 1.1824 (rough estimate)
refractive index 1.5600 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly)
form Solid
pka pKa 4.13(H2O t=25.0±0.1 I=0.1(NaCl)) (Uncertain)
color White to Off-White
EWG's Food Scores 1
FDA UNII S747T1ERAJ
Proposition 65 List Anisindione
EPA Substance Registry System Anisindione (117-37-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H351
Precautionary statements  P264-P270-P308+P313-P301+P312+P330-P501
RIDADR  2811
HazardClass  6.1(b)
PackingGroup  III
Toxicity mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),Journal of Medicinal Chemistry. Vol. 28, Pg. 1591, 1985.
NFPA 704
1
2 0

2-P-ANISYL-1,3-INDANDIONE price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A673480 Anisindione 117-37-3 1g $120 2021-12-16 Buy
Biosynth Carbosynth FA29786 Anisindione 117-37-3 1g $70 2021-12-16 Buy
Matrix Scientific 063576 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione 117-37-3 500mg $95 2021-12-16 Buy
Biosynth Carbosynth FA29786 Anisindione 117-37-3 2g $100 2021-12-16 Buy
Biosynth Carbosynth FA29786 Anisindione 117-37-3 5G $200 2021-12-16 Buy
Product number Packaging Price Buy
A673480 1g $120 Buy
FA29786 1g $70 Buy
063576 500mg $95 Buy
FA29786 2g $100 Buy
FA29786 5G $200 Buy

2-P-ANISYL-1,3-INDANDIONE Chemical Properties,Uses,Production

Chemical Properties

Slightly beige or yellow powder

Originator

Miradon,Schering,US,1960

Uses

radiopaque agent

Uses

Anisindione is a synthetic anticoagulant that prevents the formation of active procoagulation factors and proteins in the liver.

Definition

ChEBI: A cyclic beta-diketone consisting of indane-1,3-dione having a 4-methoxyphenyl substituent at the 4-position.

Manufacturing Process

To a hot solution of 20.6 g of sodium in 400 ml of absolute ethanol, there is added a solution of 110 g of phthalide and 110 g of p-methoxybenzaldehyde. A vigorous reaction ensues and one-half of the alcohol is distilled off over a two hour period. Ice and water are added to the red solution and the diluted solution is acidified with hydrochloric acid. The resulting gum solidifies and the aqueous phase is removed by decantation. The crude solid is recrystallized twice from two liters of ethanol yielding 2-(p-methoxyphenyl)-1,3-indandione as pale yellow crystals, MP 155-156°C.

brand name

Miradon (Schering).

Therapeutic Function

Anticoagulant

General Description

Anisindione, 2-(p-methoxyphenyl)-1,3-indandione, 2-(p-anisyl)-1,3-indandione (Miradon), is ap-methoxy congener of phenindione. It is a white, crystallinepowder, slightly soluble in water, tasteless, and absorbedwell after oral administration.
In instances when the urine may be alkaline, an orangecolor may be detected. This is caused by metabolic productsof anisindione and is not hematuria.

Purification Methods

Crystallise anisidinone from acetic acid or EtOH. [Horeau & Jacqius Bull Soc Chim Fr 53 1948, Koelsch J Am Chem. Soc 58 1331 1936, Beilstein 8 III 2931.]

2-P-ANISYL-1,3-INDANDIONE synthesis

87-41-2
123-11-5
117-37-3
Synthesis of 2-P-ANISYL-1,3-INDANDIONE from Phthalide and p-Anisaldehyde

2-P-ANISYL-1,3-INDANDIONE Preparation Products And Raw materials

Raw materials

p-Anisaldehyde Sodium ethoxide Phthalide 1,3-Indandione, 2-diazo- Benzenepropanenitrile, α-(4-methoxyphenyl)-β-oxo-
2-Butanone, 1-(4-methoxyphenyl)- 3-[(4-methoxyphenyl)methylene]phthalide Ethyl benzoate Methyl benzoate Ethanol
4-Methoxyphenylacetic acid Anisole 4-Methoxybenzyl cyanide Dimethyl phthalate Phthalic anhydride

1of3

Preparation Products

2-P-ANISYL-1,3-INDANDIONE Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
BOC Sciences 		+16314854226 inquiry@bocsci.com United States 19743 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Shaanxi Didu New Materials Co. Ltd 		+86-89586680 +86-13289823923 1026@dideu.com China 9020 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9425 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Nanjing Chemlin Chemical Co., Ltd 025-83697070 info@chemlin.com.cn China 17989 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Supplier Advantage
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
Nextpeptide Inc 		58
Shaanxi Didu New Materials Co. Ltd 		58
Henan Aochuang Chemical Co.,Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
Nanjing Chemlin Chemical Co., Ltd 64
Chemsky（shanghai）International Co.,Ltd. 50

View Lastest Price from 2-P-ANISYL-1,3-INDANDIONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-P-ANISYL-1,3-INDANDIONE pictures 2022-10-14 2-P-ANISYL-1,3-INDANDIONE
117-37-3
 US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

2-P-ANISYL-1,3-INDANDIONE Spectrum

2-P-ANISYL-1,3-INDANDIONE(117-37-3)1HNMR

117-37-3(2-P-ANISYL-1,3-INDANDIONE)Related Search:

Anethole trithione Indene 1H-Indene-1,3(2H)-dione, 2-hydroxy-2-(2-hydroxy-4,5-dimethoxyphenyl)- 1,3-Indandione, 2-(3,4-dimethoxy-2-hydroxyphenyl)-2-hydroxy- 2-BENZYL-2-(4-METHOXYPHENYL)-1H-INDENE-1,3(2H)-DIONE
2-P-ANISYL-1,3-INDANDIONE 1,3-Indandione, 2-hydroxy-2-(2-hydroxy-4,5,6-trimethoxyphenyl)- 2-Hydroxy-2-(2-hydroxy-4-methoxyphenyl)-1H-indene-1,3(2H)-dione 2-BROMO-2-(4-METHOXYPHENYL)INDANE-1,3-DIONE

1of2

ANISINDIONE 2-P-ANISYL-1,3-INDANDIONE 1,3-Indandione, 2-(p-methoxyphenyl)- 1H-Indene-1,3(2H)-dione, 2-(4-methoxyphenyl)- 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione 2-(4-methoxyphenyl)indan-1,3-dione 2-(p-Methoxyphenyl)-1,3-indandione 2-(p-methoxyphenyl)-3-indandione 2-(p-Methoxyphenyl)indane-1,3-dione 2-para-anisyl-1,3-indandione andion Anisin indandione anisinindandione Miradon SPE 2792 spe2792 unidione Unidone Andindione Anisindone 2-(4-methoxyphenyl)indane-1,3-quinone 2-(4-methoxyphenyl)indene-1,3-dione 1,3-Indanedione, 2-(4-methoxyphenyl)- 2-(4-methoxyphenyl)indane-1,3-dione Anisindione≥ 98% (TLC) 2-(4-methoxyphenyl)-1h-indene-3(2h)-dione 2-(4-methoxyphenyl)-3-indanedione HSDB 3205 nisindione Anisindione,inhibit,Inhibitor 117-37-3 Inhibitors OPTIRAY