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ZK 756326

CAS No.
874911-96-3
Chemical Name:
ZK 756326
Synonyms
CS-2219;ZK 756326;ZK756326 2HCl;2-(2-(4-(3-Phenoxybenzyl)piperazin-1-yl)ethoxy)ethan-1-ol;2-[2-[4-[(3-Phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol;2-[2-[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-ethoxy]-ethanol;Ethanol, 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]-;2-(2-(4-(3-phenoxybenzyl)piperazin-1-yl)ethoxy)ethanoldihydrochloride;2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride
CBNumber:
CB2785596
Molecular Formula:
C21H28N2O3
Molecular Weight:
356.46
MDL Number:
MFCD09038571
MOL File:
874911-96-3.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:03

ZK 756326 Properties

storage temp. Desiccate at RT
form White solid.
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

ZK 756326 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 2565 ZK756326 ≥99%(HPLC) 874911-96-3 10 $170 2021-12-16 Buy
Tocris 2565 ZK756326 ≥99%(HPLC) 874911-96-3 50 $710 2021-12-16 Buy
Usbiological 257171 ZK 756326 874911-96-3 10mg $438 2021-12-16 Buy
TRC P301395 2-​[2-​[4-​[(3-​Phenoxyphenyl)​methyl]​-​1-​piperazinyl]​ethoxy]​-ethanol 874911-96-3 0.5mg $45 2021-12-16 Buy
ApexBio Technology B7109 ZK756326 874911-96-3 5mg $125 2021-12-16 Buy
Product number Packaging Price Buy
2565 10 $170 Buy
2565 50 $710 Buy
257171 10mg $438 Buy
P301395 0.5mg $45 Buy
B7109 5mg $125 Buy

ZK 756326 Chemical Properties,Uses,Production

Uses

2-?[2-?[4-?[(3-?Phenoxyphenyl)?methyl]?-?1-?piperazinyl]?ethoxy]?-ethanol is a nonpeptide CCR8 chemokine receptor agonist that inhibits the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM (1). It is a useful compound to investigate the physiological role of CCR8 in HIV infection.

Biological Activity

Selective, non-peptide CCR8 chemokine receptor agonist (IC 50 values are 1.8 and 2.6 μ M for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α 2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

ZK 756326 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 51)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Shenzhen Shengda Pharma Limited
755-85269922 +8613424394241 sales@shengdapharm.com CHINA 310 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4663 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4153 55
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449 2630597085@qq.com China 1889 55
ZK 756326 2-(2-(4-(3-phenoxybenzyl)piperazin-1-yl)ethoxy)ethanoldihydrochloride 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride 2-[2-[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-ethoxy]-ethanol ZK756326 2HCl CS-2219 2-[2-[4-[(3-Phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol Ethanol, 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]- 2-(2-(4-(3-Phenoxybenzyl)piperazin-1-yl)ethoxy)ethan-1-ol 874911-96-3 C21H28N2O32HCl