Droprenilamine
- CAS No.
- 57653-27-7
- Chemical Name:
- Droprenilamine
- Synonyms
- Valcor;MG-8926;Droprenilamine;droprenylamine;Droprenilamine USP/EP/BP;N-(3,3-Diphenylpropyl)-α-methylcyclohexaneethanamine;Benzenepropanamine, N-(2-cyclohexyl-1-methylethyl)-γ-phenyl-
- CBNumber:
- CB31117340
- Molecular Formula:
- C24H33N
- Molecular Weight:
- 335.532
- MDL Number:
- MFCD00868259
- MOL File:
- 57653-27-7.mol
| Boiling point | 466.0±34.0 °C(Predicted) |
|---|---|
| Density | 0.975±0.06 g/cm3(Predicted) |
| pka | 10.52±0.29(Predicted) |
| FDA UNII | 31IPX0ZD7R |
Droprenilamine Chemical Properties,Uses,Production
Originator
Valcor,Maggioni,Italy,1979
Uses
Vasodilator (coronary).
Definition
ChEBI: Droprenilamine is a diarylmethane.
Manufacturing Process
The flask of a Parr hydrogenation apparatus was charged with 10.5 g of 3,3-diphenylpropylamine, 7.7 g of cyclohexylacetone, 50 ml methanol and 150 mg of platinum dioxide. Hydrogen at a pressure of 3 atmospheres was introduced and the mixture stirred. Upon absorption of the theoretical amount of hydrogen, stirring is discontinued, the catalyst is filtered off and the solution is evaporated to dryness. The residue is taken up with ether and the hydrochloride is precipitated with HCl in alcoholic solution. The product, as collected on a filter and washed with ether, is recrystallized from isopropanol. Yield: 17 g (92.5% of theory). MP: 175°C to 177°C.
brand name
Valcor (Maggioni Farmaceutici S.p.A., Italy).
Therapeutic Function
Coronary vasodilator
Droprenilamine Preparation Products And Raw materials
Droprenilamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |