Retinyl propionate
- CAS No.
- 7069-42-3
- Chemical Name:
- Retinyl propionate
- Synonyms
- VITAMIN A PROPIONATE;Retinol propionate;Einecs 230-363-2;Retinylpropionat;RETINYL PROPIOTE;Retinol,propanoate;RETINYL PROPIONATE;15-Retinol Propanoate;Retinol, 15-propanoate;ALL TRANS-RETINOL PROPIONATE
- CBNumber:
- CB3188398
- Molecular Formula:
- C23H34O2
- Molecular Weight:
- 342.51
- MDL Number:
- MFCD00129785
- MOL File:
- 7069-42-3.mol
| Boiling point | 453.7±14.0 °C(Predicted) |
|---|---|
| Density | 0.963±0.06 g/cm3(Predicted) |
| vapor pressure | 0-0Pa at 20-96.2℃ |
| Flash point | 128 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Pale Yellow to Yellow |
| BRN | 2475675 |
| Stability | Light Sensitive |
| LogP | 9.12 at 25℃ |
| EWG's Food Scores | 6-9 |
| FDA UNII | 32JK994WMC |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360-H413 |
| Precautionary statements | P201-P273-P308+P313 |
| Hazard Codes | Xn,T |
| Risk Statements | 38-63-53-61 |
| Safety Statements | 53-45 |
| WGK Germany | 1 |
| F | 1-8-10 |
Retinyl propionate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 87809 | Retinyl propionate ≥98.0% (sum of isomers, HPLC), ~2500U/mg | 7069-42-3 | 25g | $102 | 2024-03-01 | Buy |
| Sigma-Aldrich | 87809 | Retinyl propionate ≥98.0% (sum of isomers, HPLC), ~2500U/mg | 7069-42-3 | 100g | $291 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR1668 | Retinyl Propionate Pharmaceutical Secondary Standard; Certified Reference Material | 7069-42-3 | 1g | $128 | 2024-03-01 | Buy |
| TRC | R275550 | RetinylPropionate(StabilizedwithBHT)90% | 7069-42-3 | 100g | $950 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 72272 | RetinylPropionate(StabilizedwithBHT)90% | 7069-42-3 | 5G | $2200 | 2021-12-16 | Buy |
Retinyl propionate Chemical Properties,Uses,Production
Suggestions for use
Usage levels of retinyl propionate in skin care range from 0.1–0.4%. It is often paired with niacinamide because this B vitamin enhances the stability and bioavailability of retinyl propionate.
Description
Retinyl propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare".Similar to retinyl palmitate, retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together.
Chemical Properties
Thick Yellow Oil
Uses
Retinyl Propionate is a Vitamin A ester derivative. Retinyl Propionate is a hypermitotic agent that is used in cosmetic formulations.This compound contains an unknown cis isomer.
Biochem/physiol Actions
Retinyl propionate, a derivative of retinol, is a fatty acid that is used as a sample preparation for copper-complexed collagen[1]. In metabolic processes, retinyl propionate is metabolized primarily into retinol (ROL) in the viable epidermis and dermis whereas ROL is esterified into retinyl palmitate (RPalm) and metabolized into the inactive retinoid 14‐hydroxy‐4,14‐retro‐retinol (14‐HRR)[2]. Retinol and its derivatives effectively intervene in the skin aging process. The matrix effect of retinyl propionate can be seen in the skin cells, bone cells, and cartilage tissue. Retinyl propionate has been shown to increase calcium pantothenate transport rates in human serum and also has a film-forming polymer effect.
Side effects
Side effects of using retinol may include: redness, irritation, burning, itching, dry skin, flaking and peeling of the skin, increased sensitivity to the sun, and skin cancer.
Structure and conformation
Retinyl propionate is closest in molecular size to pure retinoic acid with just three additional carbons. Vitamin A palmitate has an additional 16 carbons, making it too large to reach the dermis effectively.
References
[1] Wang Q, et al. The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging. Journal of Cosmetic Dermatology, 2023; 22: 2040-2049.
[2] Yang Y, et al. Hydrophobically modified inulin based nanoemulsions for enhanced stability and transdermal delivery of retinyl propionate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022; 653: 129883.
Retinyl propionate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3001 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18223 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28251 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12975 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
View Lastest Price from Retinyl propionate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-22 | RETINYL PROPIONATE
7069-42-3
|
US $0.00-0.00 / kg | 1kg | 99% | 500000kg | Hebei Kingfiner Technology Development Co.Ltd | |
 |
2024-04-07 | Retinyl propionate
7069-42-3
|
US $32.00-1.40 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2024-02-15 | Retinyl Propionate
7069-42-3
|
US $900.00-2490.00 / g | 1g | 98 | 500 Kg | R&D Scientific Inc. |
-
- RETINYL PROPIONATE
7069-42-3
- US $0.00-0.00 / kg
- 99%
- Hebei Kingfiner Technology Development Co.Ltd
-
- Retinyl propionate
7069-42-3
- US $32.00-1.40 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Retinyl Propionate
7069-42-3
- US $900.00-2490.00 / g
- 98
- R&D Scientific Inc.