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AMT HYDROCHLORIDE

CAS No.
21463-31-0
Chemical Name:
AMT HYDROCHLORIDE
Synonyms
4H-1;AMT HCL;AMT HYDROCHLORIDE;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE;5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE
CBNumber:
CB3266443
Molecular Formula:
C5H11ClN2S
Molecular Weight:
166.67
MDL Number:
MFCD00792731
MOL File:
21463-31-0.mol
Last updated:2023-06-30 15:45:59

AMT HYDROCHLORIDE Properties

Melting point 146-150°C
storage temp. 0-6°C
solubility DMF: >8 mg/ml; DMSO: >16 mg/ml; Ethanol: >25 mg/ml; Water: >25 mg/ml
form A crystalline solid
Water Solubility Soluble to 10 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335
Precautionary statements  P261-P264-P271-P280-P304+P340-P305+P351+P338-P312-P337+P313-P403+P233-P405-P501
HS Code  29309099
NFPA 704
0
2 0

AMT HYDROCHLORIDE price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 5mg $62 2024-03-01 Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 10mg $109 2024-03-01 Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 50mg $448 2024-03-01 Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 100mg $711 2024-03-01 Buy
Tocris 0871 AMThydrochloride 21463-31-0 50 $527 2021-12-16 Buy
Product number Packaging Price Buy
81010 5mg $62 Buy
81010 10mg $109 Buy
81010 50mg $448 Buy
81010 100mg $711 Buy
0871 50 $527 Buy

AMT HYDROCHLORIDE Chemical Properties,Uses,Production

Description

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.

Chemical Properties

white to off-white powder

Uses

AMT Hydrochloride is a potent and selective inhibitors of inducible nitric oxide synthase, which may lead to therapeutic applications in the treatment of inflammatory and autoimmune diseases.

Biological Activity

Potent, selective and reversible inhibitor of iNOS (IC 50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).

storage

Desiccate at +4°C

AMT HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109 market03@meryer.com China 40240 62
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Shanghai Synmedia Chemical Co., Ltd. 021-38681880 13817889927 sales@synmedia-chem.com China 249 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4182 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9432 58
BOC Sciences -- info@bocsci.com USA 0 65

21463-31-0(AMT HYDROCHLORIDE)Related Search:

5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE AMT HYDROCHLORIDE AMT HCL 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL 4H-1 21463-31-0 C5H11ClN2S C5H10N2SHCl Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme Biochemicals and Reagents BioChemical L to O Nitric Oxide Synthase (iNOS)