ChemicalBook >> CAS DataBase List >>OXYTHIAMINE HYDROCHLORIDE
OXYTHIAMINE HYDROCHLORIDE
- CAS No.
- 614-05-1
- Chemical Name:
- OXYTHIAMINE HYDROCHLORIDE
- Synonyms
- OXYTHIAMINE HCL;Oxythiamine Chloride HCl;OXYTHIAMINE HYDROCHLORIDE;Oxametholone Hydrochloride;OXYTHIAMINE CHLORIDE HYDROCHLORIDE;hydroxythiaminechloridehydrochloride;OXYTHIAMINE CHLORIDE HCL CRYSTALLINE;hyl)-4-methyl-,chloride,monohydrochloride;Thiamine Impurity 19（Oxythiamine Chloride HCl）;Oxythiamine chloride hydrochloride, ≥95% (HPLC)
- CBNumber:
- CB3428625
- Molecular Formula:
- C12H17Cl2N3O2S
- Molecular Weight:
- 338.25
- MDL Number:
- MFCD00050656
- MOL File:
- 614-05-1.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:16
| Melting point | >190°C (subl.) |
|---|---|
| storage temp. | -20°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| FDA UNII | HM0RL1Q94J |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| RTECS | XJ7034100 |
OXYTHIAMINE HYDROCHLORIDE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O4000 | Oxythiamine chloride hydrochloride ≥95% (HPLC) | 614-05-1 | 1g | $50.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | O4000 | Oxythiamine chloride hydrochloride ≥95% (HPLC) | 614-05-1 | 5g | $156 | 2024-03-01 | Buy |
| Cayman Chemical | 29953 | Oxythiamine (chloride hydrochloride) | 614-05-1 | 1g | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 29953 | Oxythiamine (chloride hydrochloride) | 614-05-1 | 25g | $479 | 2024-03-01 | Buy |
| Cayman Chemical | 29953 | Oxythiamine (chloride hydrochloride) | 614-05-1 | 5g | $140 | 2024-03-01 | Buy |
OXYTHIAMINE HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
thiamine antagonist
Uses
Oxythiamine chloride hydrochloride is suitable for use:
- as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
- as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
- in the synthesis of oxythiamineH picrolonate salt
Definition
ChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.
General Description
Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.
Biochem/physiol Actions
Oxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.
OXYTHIAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
OXYTHIAMINE HYDROCHLORIDE Suppliers
Global( 41)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52861 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40240 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 021-58099652-8005 13585536065 | bin.wu@shlschem.com | China | 9816 | 59 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
614-05-1(OXYTHIAMINE HYDROCHLORIDE)Related Search:
5-(2-HYDROXYETHYL)-3-(4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL)-4-METHYLTHIAZOLIUM CHLORIDE
5-[2-HYDROXYETHYL]-3-[4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL]-4-METHYLTHIAZOLIUM CHLORIDE HYDROCHLORIDE
Oxametholone Hydrochloride
hydroxythiaminechloridehydrochloride
hyl)-4-methyl-,chloride,monohydrochloride
OXYTHIAMINE CHLORIDE HYDROCHLORIDE
OXYTHIAMINE HCL
OXYTHIAMINE HYDROCHLORIDE
OXYTHIAMINE CHLORIDE HCL CRYSTALLINE
5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride
5-[[5-(2-hydroxyethyl)-4-methyl-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride
5-(2-Hydroxyethyl)-4-methyl-3-[(2-methyl-6-oxo-1,6-dihydro-5-pyrimidinyl)methyl]-1,3-thiazol-3-ium chloride hydrochloride (1:1:1)
5-(2-Hydroxyethyl)-4-methyl-3-((2-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)thiazol-3-ium chloride hydrochloride
Thiamine Impurity 19（Oxythiamine Chloride HCl）
Oxythiamine Chloride HCl
Oxythiamine chloride hydrochloride, ≥95% (HPLC)
614-05-1
C12H17Cl2N3O2S
C12H16ClN3O2SHCl
C12H16N3O2SClHCl
C12H16N3O2SClClH
Biochemistry
Vitamin Derivatives
Vitamins