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Ataciguat
- CAS No.
- 254877-67-3
- Chemical Name:
- Ataciguat
- Synonyms
- HMR 1766;Ataciguat;Ataciguat (HMR-1766;5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide;5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide;Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-;cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
- CBNumber:
- CB41565384
- Molecular Formula:
- C21H19Cl2N3O6S3
- Molecular Weight:
- 576.5
- MDL Number:
- MFCD09837865
- MOL File:
- 254877-67-3.mol
Last updated:2023-09-04 16:42:00
| Density | 1.613±0.06 g/cm3(Predicted) |
|---|---|
| solubility | DMF: 1 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml |
| form | A crystalline solid |
| pka | 5.70±0.50(Predicted) |
| FDA UNII | QP166M390Q |
Ataciguat price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16371 | Ataciguat ≥95% | 254877-67-3 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 16371 | Ataciguat ≥95% | 254877-67-3 | 5mg | $356 | 2024-03-01 | Buy |
| Cayman Chemical | 16371 | Ataciguat ≥95% | 254877-67-3 | 10mg | $632 | 2024-03-01 | Buy |
| TRC | A790040 | Ataciguat | 254877-67-3 | 5mg | $290 | 2021-12-16 | Buy |
| ApexBio Technology | C4216 | Ataciguat | 254877-67-3 | 10mg | $720 | 2021-12-16 | Buy |
Ataciguat Chemical Properties,Uses,Production
Uses
Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, belongs to a new structural class of sGC activators capable of activating the oxidized form of sGC. Ataciguat has been shown to improve endothelial function and to reduce platelet activation in exptl. diabetes. Chronic regular treatment with sGC activators such as ataciguat could therefore eventually constitute an effective therapy targeting deficient NO/cGMP signaling in hypertension, peripheral and coronary artery disease, heart failure, thrombosis and erectile dysfunction.
Ataciguat Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 49)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189 | mychess007@163.com | China | 1994 | 55 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 |
254877-67-3(Ataciguat)Related Search:
5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide
Ataciguat
HMR 1766
Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-
Ataciguat
(HMR-1766
cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide
254877-67-3
C21H19Cl2N3O6S3
Intermediates & Fine Chemicals
Pharmaceuticals
Sulfur & Selenium Compounds
Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds