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LEUROSINE

LEUROSINE structure

CAS No.: 23360-92-1

Chemical Name:: LEUROSINE

Synonyms: amotin;LEUROSINE;nsc-528004;Vinleurosine;Vincristine EP Impurity F;Vincristine EP Impurity F (Leurosine);4'-Deoxy-3',4'-epoxyvincaleucoblastine, 9CI;(3'R,4'S)-3',4'-Oxy-4'-deoxyvincaleukoblastine;Vincristine Impurity 6(Vincristine EP Impurity F);4′-deoxy-3′α,4′α-epoxyvincaleukoblastine(leurosine)

CBNumber:: CB4205283

Molecular Formula:: C46H56N4O9

Molecular Weight:: 808.97

MDL Number:: MFCD01716248

MOL File:: 23360-92-1.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:36

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LEUROSINE Properties

Melting point	202-205℃
Density	1.39
pka	11.36±0.60(Predicted)
EWG's Food Scores	1
FDA UNII	803MS59U85

SAFETY

Risk and Safety Statements

RIDADR	1544
HazardClass	6.1(a)
PackingGroup	II
Toxicity	dog,LDLo,intraperitoneal,12mg/kg (12mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Eksperimental'naya Onkologiya. Experimental Oncology. Vol. 9(5), Pg. 76, 1987.

LEUROSINE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	V314520	Vinleurosine	23360-92-1	10mg	$1320	2021-12-16	Buy
Arctom	CFN90466	Vinleurosine ≥98%	23360-92-1	10mg	$833	2021-12-16	Buy

Product number	Packaging	Price	Buy
V314520	10mg	$1320	Buy
CFN90466	10mg	$833	Buy

LEUROSINE Chemical Properties,Uses,Production

Description

Vinqa rosea yields this complex dimeric alkaloid which forms colourless crystals that are best purified by recrystallization from acetonitrile. It crystallizes with 8 moles of H20 and loses solvent when heated at In-5°C. It is also dextro? rotatory with [α]²⁶_D + n° (CHCI3)’ A crystalline SUlphate is known which has m.p. 238-242°C (dec.) and [α]_D - 8.3° (MeOH). The N(b)-oxide is identical with pleurosine (q.v.).

Uses

Antineoplastic.

Uses

Vinleurosine is an antitumor compound derived from Vinca Rosea.

Definition

ChEBI: Leurosine is a vinca alkaloid.

References

Svoboda., J. Amer. Pharm. Assoc., 47,834 (1959)
Neuss et al., J. Amer. Chern. Soc., 81,4754 (1959)
Revised structure:
Neuss et al., Tetrahedron Lett., 783 (1968)

LEUROSINE Preparation Products And Raw materials

Raw materials

Preparation Products

LEUROSINE Suppliers

Global( 61)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17993	56
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56
Chengdu HuaXia Chemical Reagent Co. Ltd	400-1166-196 13458535857	cdhxsj@163.com	China	13359	58
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50

Supplier	Advantage
Shaanxi Pioneer Biotech Co., Ltd .	58
Standardpharm Co. Ltd.	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
TargetMol Chemicals Inc.	58
China National Standard Pharmaceutical Corporation Limited	58
ChemStrong Scientific Co.,Ltd	56
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Chengdu HuaXia Chemical Reagent Co. Ltd	58
Shanghai Kewel Chemical Co., Ltd.	50

View Lastest Price from LEUROSINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-10	LEUROSINE 23360-92-1	US $0.01 / KG	1KG	98%; 99%	500g;1kg； 25kg	Career Henan Chemical Co

LEUROSINE
23360-92-1
US $0.01 / KG
98%; 99%
Career Henan Chemical Co

23360-92-1(LEUROSINE)Related Search:

VincristineM1 4'-Deoxy Vincristine N-Desmethylvinblastine Vinorelbine EP Impurity G Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2-oxido-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-

4-Desacetyl Vinblastine 3',4'-Anhydrovinblastine Vinorelbine EP Impurity H Cophylline desacetylnavelbine

Vinorelbine EP Impurity F VINBLASTINE (2R,3R)-3-AMINO-2-HYDROXYHEXANOIC ACID LEUROSINE (R)-3-AMINO-4-(3-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE

3-AMINO-4-(4-METHOXY-PHENYL)-BUTYRIC ACID (R)-3-AMINO-4-(4-METHOXYPHENYL)BUTANOIC ACID (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE

1of4

Vinleurosine 4b-Acetoxy-3,4epoxy-3-hydroxy-16-methoxy-(4 H)-vincaleukoblast-6-ene-23,22dioic Acid Dimethyl Ester (3'R,4'S)-3',4'-Oxy-4'-deoxyvincaleukoblastine (3'alpha,4'alpha)-4'-Deoxy-3',4'-epoxyvincaleukoblastine 4'-Deoxy-3',4'-epoxyvincaleucoblastine, 9CI 4’-deoxy-3’,4’-epoxy-,(3’-alpha,4’-alpha)-vincaleukoblastin 4’-deoxy-3’,4’-epoxy-,(3’alpha,4’alpha)-vincaleukoblastin amotin LEUROSINE nsc-528004 Vincristine Impurity 6(Vincristine EP Impurity F) Vincaleukoblastine,4'-deoxy-3',4'-epoxy-, (3'a,4'a)- Vincaleukoblastine, 4'-deoxy-3',4'-epoxy-, (3'α,4'α)- Vincristine EP Impurity F Vinorelbine EP Impurity E/Leurosine/4b-Acetoxy-3,4epoxy-3-hydroxy-16-methoxy-(4 H)-vincaleukoblast-6-ene-23,22dioic Acid Dimethyl Ester Vincristine EP Impurity F (Leurosine) 4′-deoxy-3′α,4′α-epoxyvincaleukoblastine(leurosine) methyl(3aR,4R,5S,5aR,10bR,13aR)-4-(acetyloxy)-3a-ethyl-9-[(1aS,11S,13S,13aR)-1a-ethyl-11-(methoxycarbonyl)-1a,4,5,10,11,12,13,13a-octahydro-2H-3,13-methano-oxireno[9,10]azacycloundecino[5,4-b]indol-11-yl]-5-hydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,11,12,13a-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate(leurosine) Vincristine EP Impurity F(Vinorelbine EP Impurity E) 23360-92-1 C46H58N4O13S