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ChemicalBook >> CAS DataBase List >>4-PHENYL-1,2,3-THIADIAZOLE

4-PHENYL-1,2,3-THIADIAZOLE

4-PHENYL-1,2,3-THIADIAZOLE Structure
4-PHENYL-1,2,3-THIADIAZOLE structure
CAS No.
25445-77-6
Chemical Name:
4-PHENYL-1,2,3-THIADIAZOLE
Synonyms
BUTTPARK 91\16-70;4-phenylthiadiazole;4-PHENYL-1,2,3-THIADIAZOLE;1,2,3-Thiadiazole, 4-phenyl-;4-Phenyl-1,2,3-thiadiazole ,98%
CBNumber:
CB4213954
Molecular Formula:
C8H6N2S
Molecular Weight:
162.21
MDL Number:
MFCD00087232
MOL File:
25445-77-6.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17
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4-PHENYL-1,2,3-THIADIAZOLE Properties

Melting point 78°C
Boiling point 100°C 1,5mm
Density 1.241±0.06 g/cm3(Predicted)
Flash point 100°C/1.5mm
storage temp. Store at -20°C
solubility DMF: 3 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka -4.23±0.22(Predicted)
BRN 119480

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Safety Statements  22-24/25
HazardClass  IRRITANT
HS Code  29420000
NFPA 704
1
2 0

4-PHENYL-1,2,3-THIADIAZOLE price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S541524 4-PHENYL-1,2,3-THIADIAZOLE Aldrich 25445-77-6 250mg $29.8 2024-03-01 Buy
Alfa Aesar L20197 4-Phenyl-1,2,3-thiadiazole 25445-77-6 1g $109 2021-12-16 Buy
Alfa Aesar L20197 4-Phenyl-1,2,3-thiadiazole 25445-77-6 5g $416 2021-12-16 Buy
Alfa Aesar L20197 4-Phenyl-1,2,3-thiadiazole 25445-77-6 250mg $43.2 2021-12-16 Buy
Cayman Chemical 10011055 4-phenyl-1,2,3-Thiadiazole 25445-77-6 100mg $31 2023-06-20 Buy
Product number Packaging Price Buy
S541524 250mg $29.8 Buy
L20197 1g $109 Buy
L20197 5g $416 Buy
L20197 250mg $43.2 Buy
10011055 100mg $31 Buy

4-PHENYL-1,2,3-THIADIAZOLE Chemical Properties,Uses,Production

Description

Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolizes substituted amines, CYP2E1 metabolizes various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 μM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner. 1,2,3-Thiadiazole compounds and their derivatives, including 4-phenyl-1,2,3-thiadiazole, are also commonly used as fungicides, herbicides, and plant growth regulators.

Chemical Properties

Off-white to light brown solid

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 442, 1985 DOI: 10.1021/jm00382a009

4-PHENYL-1,2,3-THIADIAZOLE Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid Hydrazinium hydroxide solution Sodium chloride Acetophenone Tosyl chloride
Tetrahydrofuran Diethyl ether Methanol Thionyl chloride PETROLEUM ETHER

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Preparation Products

4-PHENYL-1,2,3-THIADIAZOLE Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109 market03@meryer.com China 40240 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30132 84
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 4550 62
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9685 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3501 55
Guangdong wengjiang Chemical Reagent Co., Ltd. 0751-2886750 13927877953 3005811397@qq.com China 13345 58
Supplier Advantage
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
Clearsynth Labs Limited 58
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Guangdong wengjiang Chemical Reagent Co., Ltd. 58

25445-77-6(4-PHENYL-1,2,3-THIADIAZOLE)Related Search:

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4-PHENYL-1,2,3-THIADIAZOLE BUTTPARK 91\16-70 4-Phenyl-1,2,3-thiadiazole ,98% 4-phenylthiadiazole 1,2,3-Thiadiazole, 4-phenyl- 25445-77-6