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MK-4827 (R-enantioMer)

MK-4827 (R-enantioMer) structure

CAS No.: 1038915-58-0

Chemical Name:: MK-4827 (R-enantioMer)

Synonyms: ent-Niraparib;(R)-Niraparib;Niraparib Impurity;Niraparib Impurity 13;Niraparib Impurity 51;MK-4827 (R-enantioMer);Niraparib R-enantiomer;R isomer of MK-4827, Niraparib;(R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE;2H-Indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]-

CBNumber:: CB42716288

Molecular Formula:: C19H20N4O

Molecular Weight:: 320.39

MDL Number:

MOL File:: 1038915-58-0.mol

Last updated:2024-05-07 20:25:49

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MK-4827 (R-enantioMer) Properties

Boiling point	463.6±45.0 °C(Predicted)
Density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 32 mg/mL (99.88 mM)
pka	15.36±0.30(Predicted)

MK-4827 (R-enantioMer) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	N481410	ent-Niraparib	1038915-58-0	500mg	$2230	2021-12-16	Buy
ChemScene	CS-3085	NiraparibR-enantiomer 99.50%	1038915-58-0	5mg	$220	2021-12-16	Buy
ChemScene	CS-3085	NiraparibR-enantiomer 99.50%	1038915-58-0	10mg	$380	2021-12-16	Buy
ChemScene	CS-3085	NiraparibR-enantiomer 99.50%	1038915-58-0	50mg	$990	2021-12-16	Buy
Crysdot	CD00013477	(R)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 97%	1038915-58-0	1g	$3294	2021-12-16	Buy

Product number	Packaging	Price	Buy
N481410	500mg	$2230	Buy
CS-3085	5mg	$220	Buy
CS-3085	10mg	$380	Buy
CS-3085	50mg	$990	Buy
CD00013477	1g	$3294	Buy

MK-4827 (R-enantioMer) Chemical Properties,Uses,Production

Uses

ent-Niraparib is an isomer of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Definition

ChEBI: 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an antineoplastic agent.

MK-4827 (R-enantioMer) Preparation Products And Raw materials

Raw materials

Preparation Products

Niraparib

MK-4827 (R-enantioMer) Suppliers

Global( 28)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+86-0755-22677845 +86-13627253706	sale@hdimpurity.com	China	2082	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
SPIRO PHARMA		eric_feng1954@126.com	China	9254	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
InvivoChem	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
Amadis Chemical Company Limited	58
SPIRO PHARMA	55

View Lastest Price from MK-4827 (R-enantioMer) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-05-07	(R)-Niraparib 1038915-58-0	US $0.00-0.00 / mg	10mg	0.98	10g	ShenZhen H&D Pharmaceutical Technology Co., LTD

(R)-Niraparib
1038915-58-0
US $0.00-0.00 / mg
0.98
ShenZhen H&D Pharmaceutical Technology Co., LTD

1038915-58-0(MK-4827 (R-enantioMer))Related Search:

Niraparib Niraparib tosylate MK-4827 (tosylate) (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide

MK-4827 (R-enantioMer) Niraparib Impurity R isomer of MK-4827, Niraparib (R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE Niraparib R-enantiomer 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide ent-Niraparib 2H-Indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]- poly ADP ribose polymerase,Inhibitor,Niraparib (R enantiomer),PARP,Niraparib (Renantiomer),Niraparib (R-enantiomer),inhibit Niraparib Impurity 51 Niraparib Impurity 13 (R)-Niraparib 1038915-58-0